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The map label for this gene is appC [H]

Identifier: 218548553

GI number: 218548553

Start: 1224433

End: 1225977

Strand: Direct

Name: appC [H]

Synonym: EFER_1185

Alternate gene names: 218548553

Gene position: 1224433-1225977 (Clockwise)

Preceding gene: 218548551

Following gene: 218548554

Centisome position: 26.68

GC content: 50.36

Gene sequence:

>1545_bases
ATGTGGGATGTTATTGACCTCTCGCGCTGGCAGTTTGCACTGACCGCGCTCTATCACTTTTTGTTTGTTCCTCTCACTTT
GGGGTTGATTTTTTTGCTGGCTGTCATGGAAACCATCTATGTGGTAACCGGCAAAACAATCTACCGTGACATGACCCGTT
TCTGGGGTAAGTTATTCGGCATTAACTTTGCTCTTGGTGTGGCGACAGGCCTGACCATGGAGTTTCAGTTTGGCACCAAC
TGGTCTTTCTATTCCAACTATGTGGGTGATATTTTCGGCGCACCGTTGGCGATGGAAGCGTTAATGGCTTTCTTCCTGGA
ATCTACCTTTGTCGGTCTGTTTTTCTTTGGCTGGCAGCGTCTCAATAAATACCAGCATCTACTGGTGACCTGGCTGGTAG
CCTTCGGTTCCAATATCTCTGCACTATGGATACTTAACGGCAATGGCTGGATGCAATATCCCACCGGGGCGCAATTTAAT
CTTGAAACCTTGCGTATGGAGATGACCAGCTTTAGTGATCTGGTACTCAATCCGGTAAGTCAGGTGAAATTTGTCCATAC
CGTTATGTCCGGTTATGTGACAGGTGCGATGTTCATTATGGCGATCAGTGCCTGGTATTTACTGCGTGGGCGTGAACGCG
ATGTGGCGCTGCGCTCGTTTGCCATTGGTTCGGTATTTGGCACCTTAGCGATTCTGGGAACGCTACAACTTGGCGACAGT
TCAGCTTATGAAGTAGCAAAAGTACAACCAGTGAAACTGGCGGCAATGGAAGGGGAGTGGCAAACAGAACCCGCTCCCGC
CCCCTTTCATCTGTTAGCCTGGCCTGAGCAAGAGCAGGAAAAAAATGCCTTCGCTATCAAAATTCCGGCGTTGCTGGGGA
TACTGGCGACCCATTCTTTAGATAAGCCTGTTCCGGGGCTGAAAAATCTAATGACAGAAACCTTGCCGCGTTTGCAACGA
GGGCGTATTGCCTGGTTGTTGATGAATGAAATTTCACAGGGTGACCGTTCGCCACACATACTACGCGCATTCCGTGCCGT
TGAGGATGACCTCGGGTATGGCATGTTGTTGGCGCGTTACGCGCCAGATATGAATAACGTGACGCCAGAGCAATACCAGG
CGGCCATGCGCGGCGCAATTCCTCAGGTAGCCCCTGTGTTCTGGAGTTTTCGCATCATGATTGGCTGTGGTTCATTACTG
TTATTGGTGATGTTGATTGCTCTGATACAGACGATTCGCGGGCGCATCGAACAACATCGTTGGGTGCTACGCATGGTGTT
CTGGAGCTTACCACTACCCTGGATTGCCATTGAAGCCGGCTGGTTTATGACTGAGTTTGGTCGTCAGCCGTGGGCGATTC
AGGATATTCTGCCAACCTGGGCGGCTCATTCTGCACTTACCGTCGGCCAACTGGCATTTTCAATGGGATTGATCCTTGGG
CTGTACACACTGTTTTTGATCGCAGAAGTCTATCTGATGCAGAAATATGCCCGGCTCGGGCCAGGAGCAATGCACAGTGA
ACAACCCGTCCAGCAACAGGGGTAA

Upstream 100 bases:

>100_bases
TACCACAATCGGCTTATCTATATACACATAGGATGTAGGGGTATAGCAAGCGAACTACTATTAGCAGGTTATTTCCCTCT
AATCGCCTACAGGAGTTCGC

Downstream 100 bases:

>100_bases
GGAAAAGAGTCATGTTTGATTACGAAACATTACGGTTTATCTGGTGGTTGCTGATCGGTGTCATCCTTGTGGTCTTTATG
GTGACCGATGGCTTTGATAT

Product: cytochrome bd-II oxidase subunit I

Products: NA

Alternate protein names: Cytochrome bd-II oxidase subunit I [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAVMETIYVVTGKTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTN
WSFYSNYVGDIFGAPLAMEALMAFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNISALWILNGNGWMQYPTGAQFN
LETLRMEMTSFSDLVLNPVSQVKFVHTVMSGYVTGAMFIMAISAWYLLRGRERDVALRSFAIGSVFGTLAILGTLQLGDS
SAYEVAKVQPVKLAAMEGEWQTEPAPAPFHLLAWPEQEQEKNAFAIKIPALLGILATHSLDKPVPGLKNLMTETLPRLQR
GRIAWLLMNEISQGDRSPHILRAFRAVEDDLGYGMLLARYAPDMNNVTPEQYQAAMRGAIPQVAPVFWSFRIMIGCGSLL
LLVMLIALIQTIRGRIEQHRWVLRMVFWSLPLPWIAIEAGWFMTEFGRQPWAIQDILPTWAAHSALTVGQLAFSMGLILG
LYTLFLIAEVYLMQKYARLGPGAMHSEQPVQQQG

Sequences:

>Translated_514_residues
MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAVMETIYVVTGKTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTN
WSFYSNYVGDIFGAPLAMEALMAFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNISALWILNGNGWMQYPTGAQFN
LETLRMEMTSFSDLVLNPVSQVKFVHTVMSGYVTGAMFIMAISAWYLLRGRERDVALRSFAIGSVFGTLAILGTLQLGDS
SAYEVAKVQPVKLAAMEGEWQTEPAPAPFHLLAWPEQEQEKNAFAIKIPALLGILATHSLDKPVPGLKNLMTETLPRLQR
GRIAWLLMNEISQGDRSPHILRAFRAVEDDLGYGMLLARYAPDMNNVTPEQYQAAMRGAIPQVAPVFWSFRIMIGCGSLL
LLVMLIALIQTIRGRIEQHRWVLRMVFWSLPLPWIAIEAGWFMTEFGRQPWAIQDILPTWAAHSALTVGQLAFSMGLILG
LYTLFLIAEVYLMQKYARLGPGAMHSEQPVQQQG
>Mature_514_residues
MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAVMETIYVVTGKTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTN
WSFYSNYVGDIFGAPLAMEALMAFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNISALWILNGNGWMQYPTGAQFN
LETLRMEMTSFSDLVLNPVSQVKFVHTVMSGYVTGAMFIMAISAWYLLRGRERDVALRSFAIGSVFGTLAILGTLQLGDS
SAYEVAKVQPVKLAAMEGEWQTEPAPAPFHLLAWPEQEQEKNAFAIKIPALLGILATHSLDKPVPGLKNLMTETLPRLQR
GRIAWLLMNEISQGDRSPHILRAFRAVEDDLGYGMLLARYAPDMNNVTPEQYQAAMRGAIPQVAPVFWSFRIMIGCGSLL
LLVMLIALIQTIRGRIEQHRWVLRMVFWSLPLPWIAIEAGWFMTEFGRQPWAIQDILPTWAAHSALTVGQLAFSMGLILG
LYTLFLIAEVYLMQKYARLGPGAMHSEQPVQQQG

Specific function: Cytochrome oxidase subunit [H]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=514, Percent_Identity=90.0778210116732, Blast_Score=946, Evalue=0.0,
Organism=Escherichia coli, GI87081779, Length=506, Percent_Identity=62.2529644268775, Blast_Score=671, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.-

Molecular weight: Translated: 58032; Mature: 58032

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAVMETIYVVTGKTIYRDMTRFWGKLFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
INFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALMAFFLESTFVGLFFFGWQR
HHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNKYQHLLVTWLVAFGSNISALWILNGNGWMQYPTGAQFNLETLRMEMTSFSDLVLNPVS
HHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCHHH
QVKFVHTVMSGYVTGAMFIMAISAWYLLRGRERDVALRSFAIGSVFGTLAILGTLQLGDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAYEVAKVQPVKLAAMEGEWQTEPAPAPFHLLAWPEQEQEKNAFAIKIPALLGILATHSL
CCCHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHCCCCEEEEHHHHHHHHHHCCC
DKPVPGLKNLMTETLPRLQRGRIAWLLMNEISQGDRSPHILRAFRAVEDDLGYGMLLARY
CCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
APDMNNVTPEQYQAAMRGAIPQVAPVFWSFRIMIGCGSLLLLVMLIALIQTIRGRIEQHR
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVLRMVFWSLPLPWIAIEAGWFMTEFGRQPWAIQDILPTWAAHSALTVGQLAFSMGLILG
HHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTLFLIAEVYLMQKYARLGPGAMHSEQPVQQQG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAVMETIYVVTGKTIYRDMTRFWGKLFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
INFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALMAFFLESTFVGLFFFGWQR
HHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNKYQHLLVTWLVAFGSNISALWILNGNGWMQYPTGAQFNLETLRMEMTSFSDLVLNPVS
HHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCHHH
QVKFVHTVMSGYVTGAMFIMAISAWYLLRGRERDVALRSFAIGSVFGTLAILGTLQLGDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAYEVAKVQPVKLAAMEGEWQTEPAPAPFHLLAWPEQEQEKNAFAIKIPALLGILATHSL
CCCHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHCCCCEEEEHHHHHHHHHHCCC
DKPVPGLKNLMTETLPRLQRGRIAWLLMNEISQGDRSPHILRAFRAVEDDLGYGMLLARY
CCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
APDMNNVTPEQYQAAMRGAIPQVAPVFWSFRIMIGCGSLLLLVMLIALIQTIRGRIEQHR
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVLRMVFWSLPLPWIAIEAGWFMTEFGRQPWAIQDILPTWAAHSALTVGQLAFSMGLILG
HHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTLFLIAEVYLMQKYARLGPGAMHSEQPVQQQG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1658595; 8905232; 9278503; 8626304 [H]