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The map label for this gene is gstA [H]

Identifier: 218532829

GI number: 218532829

Start: 5286147

End: 5286773

Strand: Reverse

Name: gstA [H]

Synonym: Mchl_4952

Alternate gene names: 218532829

Gene position: 5286773-5286147 (Counterclockwise)

Preceding gene: 218532831

Following gene: 218532828

Centisome position: 91.5

GC content: 69.38

Gene sequence:

>627_bases
GTGAAGCTCTACAGCCTGACGCTCTCGGGCCATGCCCACCGGGCACGCCTGTTCCTGTCGCTGGTCGGCCAGCCCTATGA
GACCGTCGAGGTCGACTTCGCCGGGGGGCAGAACCGCTCGCCGGATTTTCTCGCGATCAACCCGTTCGGGCAGGTTCCCG
TCCTTGACGATGACGGGACGATCGTGCCGGATTCCAACGCCATCCTCGTCTACTTCGCGAAGAAGCTCGGGCGCAGCGAT
TGGCTGCCCGAGGATGCGGCGGGGGCCGCGCAGGTGCAGCGTTGGCTCTCCGTCGCGGCCGGCCCGATCGCCTTCGGTCC
CTGCGCCGCCCGCCTCGTCACGCTGTTCGGCGCCAGCTTCGATGCGGGGGAGGTGATCGCGCGCGCCCACAGGATTCTGG
CGCTGATCGATGCGGAACTGTCGTCCCGCGACTGGCTCGCCGCCGACCGTCCGACCATCGCCGACGTGGCGCTCTACAGC
TACATCGCCGCCGCGCCCGAGGGGAACGTCGATCTCGCAGCTTACGAAAACGTCCGCGCCTGGCTCGCCCGCATCGAGGC
GCTGCCCGGCTTCGTGTCACTCCCGGCCTCGCCGGTCGGCCTGAACGCGACGGGAGCCTCCGCATGA

Upstream 100 bases:

>100_bases
CACGCAACAGTCGCTTGCCGAGAATGCCGGTTCACCTCGCGGCGGAGAAGGAGTGTGATCCACCCCACGGCCGATCCCGC
GGCCGGGAGGAGACGACGCC

Downstream 100 bases:

>100_bases
ACGGGCACGCCGCGGCCTCTCCCTGGCACCGGGGCGAGGTGGCGATCCAAGAGAGTGTCGGCATGGCCGGCCGGATGGCC
GAGCTCGGTCCGCGGGTGAT

Product: glutathione S-transferase domain

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKLYSLTLSGHAHRARLFLSLVGQPYETVEVDFAGGQNRSPDFLAINPFGQVPVLDDDGTIVPDSNAILVYFAKKLGRSD
WLPEDAAGAAQVQRWLSVAAGPIAFGPCAARLVTLFGASFDAGEVIARAHRILALIDAELSSRDWLAADRPTIADVALYS
YIAAAPEGNVDLAAYENVRAWLARIEALPGFVSLPASPVGLNATGASA

Sequences:

>Translated_208_residues
MKLYSLTLSGHAHRARLFLSLVGQPYETVEVDFAGGQNRSPDFLAINPFGQVPVLDDDGTIVPDSNAILVYFAKKLGRSD
WLPEDAAGAAQVQRWLSVAAGPIAFGPCAARLVTLFGASFDAGEVIARAHRILALIDAELSSRDWLAADRPTIADVALYS
YIAAAPEGNVDLAAYENVRAWLARIEALPGFVSLPASPVGLNATGASA
>Mature_208_residues
MKLYSLTLSGHAHRARLFLSLVGQPYETVEVDFAGGQNRSPDFLAINPFGQVPVLDDDGTIVPDSNAILVYFAKKLGRSD
WLPEDAAGAAQVQRWLSVAAGPIAFGPCAARLVTLFGASFDAGEVIARAHRILALIDAELSSRDWLAADRPTIADVALYS
YIAAAPEGNVDLAAYENVRAWLARIEALPGFVSLPASPVGLNATGASA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=184, Percent_Identity=31.5217391304348, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI124249394, Length=184, Percent_Identity=31.5217391304348, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788640, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081789, Length=208, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082195, Length=187, Percent_Identity=25.668449197861, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654992, Length=193, Percent_Identity=34.1968911917098, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19922526, Length=199, Percent_Identity=32.6633165829146, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20130115, Length=197, Percent_Identity=31.4720812182741, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24654983, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654979, Length=196, Percent_Identity=30.6122448979592, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922532, Length=196, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646259, Length=186, Percent_Identity=30.1075268817204, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221378983, Length=186, Percent_Identity=30.1075268817204, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571670, Length=159, Percent_Identity=27.6729559748428, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17864592, Length=148, Percent_Identity=28.3783783783784, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654965, Length=176, Percent_Identity=31.25, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17864596, Length=193, Percent_Identity=22.7979274611399, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17933730, Length=186, Percent_Identity=21.505376344086, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654975, Length=172, Percent_Identity=32.5581395348837, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17864594, Length=158, Percent_Identity=26.5822784810127, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17864598, Length=158, Percent_Identity=29.1139240506329, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19922528, Length=195, Percent_Identity=29.7435897435897, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22005; Mature: 22005

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYSLTLSGHAHRARLFLSLVGQPYETVEVDFAGGQNRSPDFLAINPFGQVPVLDDDGT
CEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCEEECCCCC
IVPDSNAILVYFAKKLGRSDWLPEDAAGAAQVQRWLSVAAGPIAFGPCAARLVTLFGASF
CCCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DAGEVIARAHRILALIDAELSSRDWLAADRPTIADVALYSYIAAAPEGNVDLAAYENVRA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHH
WLARIEALPGFVSLPASPVGLNATGASA
HHHHHHHCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLYSLTLSGHAHRARLFLSLVGQPYETVEVDFAGGQNRSPDFLAINPFGQVPVLDDDGT
CEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCEEECCCCC
IVPDSNAILVYFAKKLGRSDWLPEDAAGAAQVQRWLSVAAGPIAFGPCAARLVTLFGASF
CCCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DAGEVIARAHRILALIDAELSSRDWLAADRPTIADVALYSYIAAAPEGNVDLAAYENVRA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHH
WLARIEALPGFVSLPASPVGLNATGASA
HHHHHHHCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA