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The map label for this gene is yclF [H]

Identifier: 218234132

GI number: 218234132

Start: 637872

End: 639257

Strand: Reverse

Name: yclF [H]

Synonym: BCB4264_A0651

Alternate gene names: 218234132

Gene position: 639257-637872 (Counterclockwise)

Preceding gene: 218234576

Following gene: 218232487

Centisome position: 11.8

GC content: 35.93

Gene sequence:

>1386_bases
ATGGATGCAGCTTTAAAATTAGACAAAGCTGGAGAGCAACAATCACCAAAAAAACATCCACCAGGGTTGTACTTGTTGTT
CTTAACAGAAATGTGGGAAAGATTTAGTTATTATGGAATGCGCGGCCTTTTAGTTCTTTATTTAACGACTGCTGCGGTTA
GTGGCGGGTTAGGATTTGATAAGGCGTTTGCAGTGCAATTATATGGTACTTTTACAGCGGCAGTATATTTCATGCCAATT
ATAGGTGGATGGCTAACAGATCATTATATTACAAGACGTCATGCCATTACTCTCGGCGGAATTATTATGGCAATCGGCAA
CTTTGTACTATTCTCAATGAATACAAAAACAGGACTATTTCTAGGATTAATACTATTAGTTATTGGTAATGGGTTCTTTA
AACCAAATATTTCTACACTGTTAGGTGAATTGTATGGTGAAAATGATTCGCGTCGTGACAGTGCATTTACTATCTTCTAT
ATGGGTATTAACGTAGGTGCTTTCTTCGCTCCACTTATTTGTGGATTTTTAGCAGAAGATTTCTTTAAAACAAGCGTTGA
TGGCGTTATGGTTATGGGATATAAATACGGATTCTTAGCAGCTTGTATCGGTATGATTATTGGACAAATTGTTTTCAACT
TATTAGCTCCTCGCTACCTTGGTACAGCAGGAACAACAATTGTTGGTAAAAAAACAAAAAATCAACCTACAATCGAAAAG
AAACCTTTAACAAAACAAGAAAAAAATCGCACTTGGGCAATTGTAATTTTAACTTGTTTCGTAGTATTCTTCTGGGCAGG
CTTTGAACAAGCTGGTAGTTCTTTAACACTTTATACAGATAAATTTGTTGATCGTACAATTTTTGGATGGGAAGTTCCAA
CATCTTGGTTCCAATCCGTTAATCCAGCGTTCATCGTACTCCTTGCACCATTCGTATCTATGCTATGGTTAAAACTTTCT
AAATCAAAGCGTGGCGATTTAAAAATACCAACAAAAATGGCATTTGGTATGATTTTACTAGGTATAGGTTACCTGGTTTT
AACATTAGCGGTTCTAAAAACCGGAAGTAGTGAAGCTGATATAACTGTTAAAGCAAACTTATTATTCATCGTTATCACTT
ATATGTTCCATACAATTGGAGAACTATTCTTATCACCAATCGGTCTATCAATGGTAAGTGCAATTGCACCTGTTAAATTA
GCATCATTATTAATGGGTGTATGGTTAGCTGGTTCAGGTATGGCTAACTGGTTAGCTGGTAAACTTGCTTCCTTTACACA
ATCATTAGGATACCTTGAAGTATTTGCAAGTATTGGCATTATCGTTATCGTCTTAGGACTTGTACTCCTTCTCTTCTCTA
AAAAAGTTGCGAGTATGATGGAATAA

Upstream 100 bases:

>100_bases
TTTTCTTTCTATTTCCATATAATTCTATTGACTTCTAAATATTTTGTAAATTAAAATGATTACATAAATATCCGTTATAC
AGGATTAGGGGGAAACAAAA

Downstream 100 bases:

>100_bases
TACAAAAACAGACGCTTCTAAAATCAGAAGCGTCTTTTCTATTACTTCTCCTCTAAAGCTGTCACGTCCACATGAACGCT
CTCACCAGGATTAGATACAT

Product: proton/peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFDKAFAVQLYGTFTAAVYFMPI
IGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLFLGLILLVIGNGFFKPNISTLLGELYGENDSRRDSAFTIFY
MGINVGAFFAPLICGFLAEDFFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTIVGKKTKNQPTIEK
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEVPTSWFQSVNPAFIVLLAPFVSMLWLKLS
KSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEADITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKL
ASLLMGVWLAGSGMANWLAGKLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME

Sequences:

>Translated_461_residues
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFDKAFAVQLYGTFTAAVYFMPI
IGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLFLGLILLVIGNGFFKPNISTLLGELYGENDSRRDSAFTIFY
MGINVGAFFAPLICGFLAEDFFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTIVGKKTKNQPTIEK
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEVPTSWFQSVNPAFIVLLAPFVSMLWLKLS
KSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEADITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKL
ASLLMGVWLAGSGMANWLAGKLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME
>Mature_461_residues
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFDKAFAVQLYGTFTAAVYFMPI
IGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLFLGLILLVIGNGFFKPNISTLLGELYGENDSRRDSAFTIFY
MGINVGAFFAPLICGFLAEDFFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTIVGKKTKNQPTIEK
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEVPTSWFQSVNPAFIVLLAPFVSMLWLKLS
KSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEADITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKL
ASLLMGVWLAGSGMANWLAGKLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=375, Percent_Identity=25.6, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI226371746, Length=359, Percent_Identity=24.5125348189415, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI226371748, Length=350, Percent_Identity=23.7142857142857, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1790572, Length=461, Percent_Identity=32.5379609544469, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1786927, Length=497, Percent_Identity=30.9859154929577, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1787922, Length=488, Percent_Identity=29.9180327868852, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1789911, Length=474, Percent_Identity=29.3248945147679, Blast_Score=185, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI71987453, Length=384, Percent_Identity=23.9583333333333, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541704, Length=386, Percent_Identity=27.2020725388601, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17569141, Length=205, Percent_Identity=30.2439024390244, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28571102, Length=391, Percent_Identity=25.0639386189258, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28571100, Length=391, Percent_Identity=25.0639386189258, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28571098, Length=370, Percent_Identity=25.6756756756757, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639585, Length=328, Percent_Identity=27.1341463414634, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639583, Length=328, Percent_Identity=27.1341463414634, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639581, Length=338, Percent_Identity=26.6272189349112, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 50546; Mature: 50546

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFD
CCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KAFAVQLYGTFTAAVYFMPIIGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
LGLILLVIGNGFFKPNISTLLGELYGENDSRRDSAFTIFYMGINVGAFFAPLICGFLAED
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
FFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTIVGKKTKNQPTIEK
HHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEVPTSWFQSV
CCCCCHHCCCCHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHHHCEECCCCCHHHHHCC
NPAFIVLLAPFVSMLWLKLSKSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEAD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKLASLLMGVWLAGSGMANWLAG
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFD
CCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KAFAVQLYGTFTAAVYFMPIIGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
LGLILLVIGNGFFKPNISTLLGELYGENDSRRDSAFTIFYMGINVGAFFAPLICGFLAED
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
FFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTIVGKKTKNQPTIEK
HHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEVPTSWFQSV
CCCCCHHCCCCHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHHHCEECCCCCHHHHHCC
NPAFIVLLAPFVSMLWLKLSKSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEAD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKLASLLMGVWLAGSGMANWLAG
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]