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The map label for this gene is mtlD

Identifier: 21672811

GI number: 21672811

Start: 605272

End: 606438

Strand: Reverse

Name: mtlD

Synonym: BUsg551

Alternate gene names: 21672811

Gene position: 606438-605272 (Counterclockwise)

Preceding gene: 21672812

Following gene: 21672810

Centisome position: 94.54

GC content: 24.76

Gene sequence:

>1167_bases
ATGAGAGCTTTACATTTTGGAGCAGGAAATATTGGACGAGGTTTTATCGCACGAGTATTATTAAAATCTGATTTTAATTT
GATATTTTCAGATGTTGATCAGAATATAATAAATGCTATTAATAATTATAAAAAATACAAAATTAAATTAATAGATAATA
GTTTCGAAAAAATTATAAATATTAACAATATCAGTGCTATAAATTCTTATGATCCAAATGTTTTAAATGTCATTTCTCAT
GTAGATTTAATTACAACAGCAGCTGGAGTTAATGCTCTTTATAAAATAGCTTCTATTCTCATAGAGGGAATTATTTTAAG
AATTAACTTAAAGTGTAAAAAACCGTTGAATATAATTGCCTGTGAAAATAAAATTAAAGCAACTTCTTTTTTAAAAAAAA
TTATTTTTGATAAAATTCCTCTTAAATATCATGATTATTTTGATGAATATATTGGTTTTGTAGATTGTACTATTGATACC
ATCGTCCCGACATTTTCTTCGTTTAAAGAAGAAAATAGTTTGTTTGTCATTGCTGAAAATTTCAAAGAATGGATTGTTGA
TGTAAATCAATTTAAAGGAATGGTACCTAAAATTATCGATATGACACTAAGTGATAATTTAACATCTTTTATAGATAGAA
AAATTTTAACTCTTAATACAGGTCATGCTATTGCAGCATACTTAGGTCTGATGAAAAATTATAAAAACATATGTGAAGCA
ATGTCAGATTTTAGTATACAAAGAATTGTAAAAGATGCTATGTACGAAAGCGGATTGGTATTAATTAAACGCTATAATTT
CAATAAAAAAGATCATCTATCTTATATTGATAAAATTTTTGTTCGTTTTAAGAATCCCTTTATCTTAGATAAACTTGAAC
GTATTGCACGAAATCCATTACAAAAATTAAGTAAGGATGAACGTTTAATTCAGCCTTTTGTAGAAGCCATGAAATATAAT
TTACCATATTTTAATTTAGTTAAGGGTATTGCAGCAGCATTGCATTATCGAAATATAAACGATATACAATCAATTAAATT
ATCTTCCTTAATCAAAGAAGAGGGACTTGAAGAAACTTTAGTTAAGGTATGTAAATTAAATGCAAATAGTAATGAAATTA
GGATAATTATTTCAGAATATCATTCTATAATAAAAGATTTTTTATAA

Upstream 100 bases:

>100_bases
GATGTTATTAGTAAATTATCAAAAACAAAAAGTGTAAAAGAAGTTTTATCATATTTAAATGTAAATGTTAAAAAAAACTA
ATTTAAATTGGAATAATTTT

Downstream 100 bases:

>100_bases
ATTTATACTAAAAATCATTTCTTATAATTTTAGAGAATAAGGTCAAATGCAACCTATTCGTATGTTATCATCTAGTTTAT
CCAGTCAAATTTCAGCTGGA

Product: mannitol-1-phosphate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRALHFGAGNIGRGFIARVLLKSDFNLIFSDVDQNIINAINNYKKYKIKLIDNSFEKIININNISAINSYDPNVLNVISH
VDLITTAAGVNALYKIASILIEGIILRINLKCKKPLNIIACENKIKATSFLKKIIFDKIPLKYHDYFDEYIGFVDCTIDT
IVPTFSSFKEENSLFVIAENFKEWIVDVNQFKGMVPKIIDMTLSDNLTSFIDRKILTLNTGHAIAAYLGLMKNYKNICEA
MSDFSIQRIVKDAMYESGLVLIKRYNFNKKDHLSYIDKIFVRFKNPFILDKLERIARNPLQKLSKDERLIQPFVEAMKYN
LPYFNLVKGIAAALHYRNINDIQSIKLSSLIKEEGLEETLVKVCKLNANSNEIRIIISEYHSIIKDFL

Sequences:

>Translated_388_residues
MRALHFGAGNIGRGFIARVLLKSDFNLIFSDVDQNIINAINNYKKYKIKLIDNSFEKIININNISAINSYDPNVLNVISH
VDLITTAAGVNALYKIASILIEGIILRINLKCKKPLNIIACENKIKATSFLKKIIFDKIPLKYHDYFDEYIGFVDCTIDT
IVPTFSSFKEENSLFVIAENFKEWIVDVNQFKGMVPKIIDMTLSDNLTSFIDRKILTLNTGHAIAAYLGLMKNYKNICEA
MSDFSIQRIVKDAMYESGLVLIKRYNFNKKDHLSYIDKIFVRFKNPFILDKLERIARNPLQKLSKDERLIQPFVEAMKYN
LPYFNLVKGIAAALHYRNINDIQSIKLSSLIKEEGLEETLVKVCKLNANSNEIRIIISEYHSIIKDFL
>Mature_388_residues
MRALHFGAGNIGRGFIARVLLKSDFNLIFSDVDQNIINAINNYKKYKIKLIDNSFEKIININNISAINSYDPNVLNVISH
VDLITTAAGVNALYKIASILIEGIILRINLKCKKPLNIIACENKIKATSFLKKIIFDKIPLKYHDYFDEYIGFVDCTIDT
IVPTFSSFKEENSLFVIAENFKEWIVDVNQFKGMVPKIIDMTLSDNLTSFIDRKILTLNTGHAIAAYLGLMKNYKNICEA
MSDFSIQRIVKDAMYESGLVLIKRYNFNKKDHLSYIDKIFVRFKNPFILDKLERIARNPLQKLSKDERLIQPFVEAMKYN
LPYFNLVKGIAAALHYRNINDIQSIKLSSLIKEEGLEETLVKVCKLNANSNEIRIIISEYHSIIKDFL

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1790028, Length=383, Percent_Identity=42.5587467362924, Blast_Score=354, Evalue=6e-99,
Organism=Saccharomyces cerevisiae, GI6324401, Length=248, Percent_Identity=22.9838709677419, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320765, Length=248, Percent_Identity=22.9838709677419, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTLD_BUCAP (Q8K912)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660878.1
- ProteinModelPortal:   Q8K912
- EnsemblBacteria:   EBBUCT00000000231
- GeneID:   1005536
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg551
- GeneTree:   EBGT00050000007918
- HOGENOM:   HBG568825
- OMA:   FTVNTGH
- ProtClustDB:   PRK02318
- BioCyc:   BAPH198804:BUSG551-MONOMER
- HAMAP:   MF_00196
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR023028
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PRINTS:   PR00084

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C; SSF48179 6DGDH_C_like

EC number: =1.1.1.17

Molecular weight: Translated: 44573; Mature: 44573

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALHFGAGNIGRGFIARVLLKSDFNLIFSDVDQNIINAINNYKKYKIKLIDNSFEKIIN
CCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHEE
INNISAINSYDPNVLNVISHVDLITTAAGVNALYKIASILIEGIILRINLKCKKPLNIIA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCEEEE
CENKIKATSFLKKIIFDKIPLKYHDYFDEYIGFVDCTIDTIVPTFSSFKEENSLFVIAEN
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
FKEWIVDVNQFKGMVPKIIDMTLSDNLTSFIDRKILTLNTGHAIAAYLGLMKNYKNICEA
HHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHH
MSDFSIQRIVKDAMYESGLVLIKRYNFNKKDHLSYIDKIFVRFKNPFILDKLERIARNPL
HHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QKLSKDERLIQPFVEAMKYNLPYFNLVKGIAAALHYRNINDIQSIKLSSLIKEEGLEETL
HHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHH
VKVCKLNANSNEIRIIISEYHSIIKDFL
HHHHHCCCCCCEEEEEHHHHHHHHHHCC
>Mature Secondary Structure
MRALHFGAGNIGRGFIARVLLKSDFNLIFSDVDQNIINAINNYKKYKIKLIDNSFEKIIN
CCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHEE
INNISAINSYDPNVLNVISHVDLITTAAGVNALYKIASILIEGIILRINLKCKKPLNIIA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCEEEE
CENKIKATSFLKKIIFDKIPLKYHDYFDEYIGFVDCTIDTIVPTFSSFKEENSLFVIAEN
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
FKEWIVDVNQFKGMVPKIIDMTLSDNLTSFIDRKILTLNTGHAIAAYLGLMKNYKNICEA
HHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHH
MSDFSIQRIVKDAMYESGLVLIKRYNFNKKDHLSYIDKIFVRFKNPFILDKLERIARNPL
HHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QKLSKDERLIQPFVEAMKYNLPYFNLVKGIAAALHYRNINDIQSIKLSSLIKEEGLEETL
HHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHH
VKVCKLNANSNEIRIIISEYHSIIKDFL
HHHHHCCCCCCEEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438