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The map label for this gene is hflK

Identifier: 21672809

GI number: 21672809

Start: 601067

End: 602302

Strand: Reverse

Name: hflK

Synonym: BUsg548

Alternate gene names: 21672809

Gene position: 602302-601067 (Counterclockwise)

Preceding gene: 21672810

Following gene: 21672808

Centisome position: 93.9

GC content: 28.24

Gene sequence:

>1236_bases
ATGGCCTGGAATAAATTTAATAATAGTGAACCAGAGCTTGATCCGTGGGGGAAAAAAAATAGTCAAGAAAAAAATGGTTC
AAAAAATAAAGATGATCGAAAAAATCATGAAAAAATAATTACATTAGACTTTAAGAAATTTTTATATAACATTAATAATA
TATTTAATAAAACAAATAATTCTCAAAATTTATCAAAAAATAAAATTAACCCATTTTTAATAATAGCTTTTGTGTCTTTT
TTTGTTTGGTGTTTCAGTGGTTTTTATACTATTAAAGAAGCTGAACGTGGAGTAGTTACTACTTTTGGAAAATTCAGTCA
TTTAGTTGCACCAGGATTAAATTGGAGACCAGTTTTTATTAATGAAGTAAAAGCTGTCAATGTTGAAACTGTACGAGAAT
TGGCAACATCAGGTGTCATGTTAACTTCAGACGAAAATGTAGTACGTGTAGAAATGAACGTACAATATAAAATTACTGAT
CCTGCTGATTATCTTTTTTCTGTTGCTTATCCAGATGATAGTTTACGTCAAGCTACTGATAGTGCATTGCGTGGAGTTAT
TGGACATTCAAATATGGATCGTGTATTAACTGAAGGACGTACTTTAATTCGAAGTGATACTCAAAAAGAAATTGAAGAAA
CAATTAAACCTTACAAATTAGGAATAACTATATTAGATGTAAATTTTCAGACCGCTAGACCTCCAGAAGAAGTTAAAGAA
GCTTTTGACGATGCTATTGCAGCGCGTGAGAATCGTGAACAATATATACGTGAAGCTGAAGCTTATTCAAATGAGGTTCA
GCCAAAAGCACATGGAAAAGCGCAGAGAATTTTAGAAGAAGCTAAAGCGTATTCTTCACGAAGAATATTAGAAGCTCAAG
GAGAAGTAGTTCGTTTTTTAAAAATTCTTCCTGAATATAGAAAGAATAAAGAAATGACTTTAAAACGTCTTTACATAGAA
TCAATGGAAAAATTATTAAGTAAGACTAAGAAAATTTTTATTGATAAAAAAAATCATTCAAAACTATTTCTCTCTTTAAA
TAATTTTTTTCATCAAGATAAATTTAATAAACAGGATCTTTTTAATAATCCAATTAATTTAAGTAAAAACCATTCTTGTT
CTTTTCAAAAAAATAAAGAAATAAATGATGTTTCTTCGTTACCTCCTAGTGATTTTTTTAAAAAACGTCGTATAGAATCT
ATACGTACTAATATTAAAAATATAGAAAGAGAATGA

Upstream 100 bases:

>100_bases
AAAAATACAGTTTTCATACTGTACAATATAGGATATATTATTTCTATTTATATTTTTTTAAAAATTAATAAGTATTAAAA
CTAATAAAATGAGGCATAAA

Downstream 100 bases:

>100_bases
AAAATATGAATAAAATAGTTATTTGTATACTAAGTTTTTTTCTTCTTATTTTCTCATCTTCTTTTTTTATTGTTAAAGAA
GGAGAACGTGGAATTATACT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MAWNKFNNSEPELDPWGKKNSQEKNGSKNKDDRKNHEKIITLDFKKFLYNINNIFNKTNNSQNLSKNKINPFLIIAFVSF
FVWCFSGFYTIKEAERGVVTTFGKFSHLVAPGLNWRPVFINEVKAVNVETVRELATSGVMLTSDENVVRVEMNVQYKITD
PADYLFSVAYPDDSLRQATDSALRGVIGHSNMDRVLTEGRTLIRSDTQKEIEETIKPYKLGITILDVNFQTARPPEEVKE
AFDDAIAARENREQYIREAEAYSNEVQPKAHGKAQRILEEAKAYSSRRILEAQGEVVRFLKILPEYRKNKEMTLKRLYIE
SMEKLLSKTKKIFIDKKNHSKLFLSLNNFFHQDKFNKQDLFNNPINLSKNHSCSFQKNKEINDVSSLPPSDFFKKRRIES
IRTNIKNIERE

Sequences:

>Translated_411_residues
MAWNKFNNSEPELDPWGKKNSQEKNGSKNKDDRKNHEKIITLDFKKFLYNINNIFNKTNNSQNLSKNKINPFLIIAFVSF
FVWCFSGFYTIKEAERGVVTTFGKFSHLVAPGLNWRPVFINEVKAVNVETVRELATSGVMLTSDENVVRVEMNVQYKITD
PADYLFSVAYPDDSLRQATDSALRGVIGHSNMDRVLTEGRTLIRSDTQKEIEETIKPYKLGITILDVNFQTARPPEEVKE
AFDDAIAARENREQYIREAEAYSNEVQPKAHGKAQRILEEAKAYSSRRILEAQGEVVRFLKILPEYRKNKEMTLKRLYIE
SMEKLLSKTKKIFIDKKNHSKLFLSLNNFFHQDKFNKQDLFNNPINLSKNHSCSFQKNKEINDVSSLPPSDFFKKRRIES
IRTNIKNIERE
>Mature_410_residues
AWNKFNNSEPELDPWGKKNSQEKNGSKNKDDRKNHEKIITLDFKKFLYNINNIFNKTNNSQNLSKNKINPFLIIAFVSFF
VWCFSGFYTIKEAERGVVTTFGKFSHLVAPGLNWRPVFINEVKAVNVETVRELATSGVMLTSDENVVRVEMNVQYKITDP
ADYLFSVAYPDDSLRQATDSALRGVIGHSNMDRVLTEGRTLIRSDTQKEIEETIKPYKLGITILDVNFQTARPPEEVKEA
FDDAIAARENREQYIREAEAYSNEVQPKAHGKAQRILEEAKAYSSRRILEAQGEVVRFLKILPEYRKNKEMTLKRLYIES
MEKLLSKTKKIFIDKKNHSKLFLSLNNFFHQDKFNKQDLFNNPINLSKNHSCSFQKNKEINDVSSLPPSDFFKKRRIESI
RTNIKNIERE

Specific function: HflC and HflK could encode or regulate a protease

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily

Homologues:

Organism=Escherichia coli, GI1790616, Length=359, Percent_Identity=59.0529247910863, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFLK_BUCAP (Q8K914)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660876.1
- ProteinModelPortal:   Q8K914
- SMR:   Q8K914
- EnsemblBacteria:   EBBUCT00000000129
- GeneID:   1005640
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg548
- GeneTree:   EBGT00050000007793
- HOGENOM:   HBG465357
- OMA:   DVMWHIS
- ProtClustDB:   CLSK316512
- BioCyc:   BAPH198804:BUSG548-MONOMER
- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972
- PANTHER:   PTHR10264
- PRINTS:   PR00721
- SMART:   SM00244
- TIGRFAMs:   TIGR01933

Pfam domain/function: PF01145 Band_7

EC number: NA

Molecular weight: Translated: 47798; Mature: 47667

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbee0cd0)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNKFNNSEPELDPWGKKNSQEKNGSKNKDDRKNHEKIITLDFKKFLYNINNIFNKTNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCC
SQNLSKNKINPFLIIAFVSFFVWCFSGFYTIKEAERGVVTTFGKFSHLVAPGLNWRPVFI
CCCCHHCCCCHHHHHHHHHHHHHHHHCHHEEHHHCCCCEEHHHHHHHHHCCCCCCCEEEE
NEVKAVNVETVRELATSGVMLTSDENVVRVEMNVQYKITDPADYLFSVAYPDDSLRQATD
CCCEECCHHHHHHHHHCCEEEECCCCEEEEEEEEEEEECCHHHHEEEEECCCHHHHHHHH
SALRGVIGHSNMDRVLTEGRTLIRSDTQKEIEETIKPYKLGITILDVNFQTARPPEEVKE
HHHHHHHCCCCHHHHHHHCHHHHHCCHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHH
AFDDAIAARENREQYIREAEAYSNEVQPKAHGKAQRILEEAKAYSSRRILEAQGEVVRFL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILPEYRKNKEMTLKRLYIESMEKLLSKTKKIFIDKKNHSKLFLSLNNFFHQDKFNKQDL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHCCCCHHHH
FNNPINLSKNHSCSFQKNKEINDVSSLPPSDFFKKRRIESIRTNIKNIERE
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
AWNKFNNSEPELDPWGKKNSQEKNGSKNKDDRKNHEKIITLDFKKFLYNINNIFNKTNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCC
SQNLSKNKINPFLIIAFVSFFVWCFSGFYTIKEAERGVVTTFGKFSHLVAPGLNWRPVFI
CCCCHHCCCCHHHHHHHHHHHHHHHHCHHEEHHHCCCCEEHHHHHHHHHCCCCCCCEEEE
NEVKAVNVETVRELATSGVMLTSDENVVRVEMNVQYKITDPADYLFSVAYPDDSLRQATD
CCCEECCHHHHHHHHHCCEEEECCCCEEEEEEEEEEEECCHHHHEEEEECCCHHHHHHHH
SALRGVIGHSNMDRVLTEGRTLIRSDTQKEIEETIKPYKLGITILDVNFQTARPPEEVKE
HHHHHHHCCCCHHHHHHHCHHHHHCCHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHH
AFDDAIAARENREQYIREAEAYSNEVQPKAHGKAQRILEEAKAYSSRRILEAQGEVVRFL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILPEYRKNKEMTLKRLYIESMEKLLSKTKKIFIDKKNHSKLFLSLNNFFHQDKFNKQDL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHCCCCHHHH
FNNPINLSKNHSCSFQKNKEINDVSSLPPSDFFKKRRIESIRTNIKNIERE
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438