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The map label for this gene is tcsR [H]

Identifier: 21244897

GI number: 21244897

Start: 4916239

End: 4916907

Strand: Direct

Name: tcsR [H]

Synonym: XAC4180

Alternate gene names: 21244897

Gene position: 4916239-4916907 (Clockwise)

Preceding gene: 21244896

Following gene: 21244899

Centisome position: 94.99

GC content: 65.17

Gene sequence:

>669_bases
ATGACCACCCTGCTAATCGCCGACGACCATCCCCTGTTCCGCGAAGCCTTGCGCGGGGCGGTGCAGCGTGTGATGCCGGG
GGTAGAACTGTTCGAAGCCGATAACGTGGATGCGCTGTATAGCCTGGCCGATGCGCAGCCGGACGCCGATCTGTTGCTGA
TGGATCTCAACATGCCCGGCGCACAGGGGTTCAGCGCGTTGGTGCACATGCGCTCGCTGCATCCGCAGTTGCCGGTGGTG
GTGGTCTCCGCACGCGAAGAACCCACCGTGATGCGGCGCGCGATCGACCACGGCGCGTTCGGCTTCATTCCCAAATCCGC
CGATTCGGACACCATCGGGCGGGCGCTGGCCACCGTGCTCGATGGCGAGCGCTGGATCCCGGCCGAAGCGCAAAACCTGC
CGCCCACCGACAGCGAGGAACGCGAGGTTGGCCAGCGTCTGCGCGATCTCACGCCACAGCAATTTCGCGTGCTGCAGATG
CTGGGCGCTGGACGCCTCAACAAACAGATCGCCTACGACCTGGGCGTGTCCGAAGCCACCATCAAGGCGCATGTCACCGC
GATCTTGCGCAAGCTCGGCGTCACCAATCGCACCCAGGCAGTGCTGATGGCCGGCAAGCTCGCCATCGATGCCGACGGCA
TCGTGCTGCCGCCGCCGGAAGAAGACTGA

Upstream 100 bases:

>100_bases
GTGCCTTCGTTAGTTGTTGCTTGCTTGCCTGCTTCTGGCCTCGCGTTTGATTTTGCGATTCCCGATTCCCCACTCCCGAT
TCCCGATTCCCGGCCCCACC

Downstream 100 bases:

>100_bases
CGCGTGCAGGTGTAGGTCTGCGTGCGTTGGGGTTGATCGGTGACGCTTGGTCGCGTCATGGCGCGCTCCTGCCTGTGATC
CCGCTACCTCGGCCGTCATC

Product: two-component system regulatory protein

Products: NA

Alternate protein names: Protein AgmR [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTTLLIADDHPLFREALRGAVQRVMPGVELFEADNVDALYSLADAQPDADLLLMDLNMPGAQGFSALVHMRSLHPQLPVV
VVSAREEPTVMRRAIDHGAFGFIPKSADSDTIGRALATVLDGERWIPAEAQNLPPTDSEEREVGQRLRDLTPQQFRVLQM
LGAGRLNKQIAYDLGVSEATIKAHVTAILRKLGVTNRTQAVLMAGKLAIDADGIVLPPPEED

Sequences:

>Translated_222_residues
MTTLLIADDHPLFREALRGAVQRVMPGVELFEADNVDALYSLADAQPDADLLLMDLNMPGAQGFSALVHMRSLHPQLPVV
VVSAREEPTVMRRAIDHGAFGFIPKSADSDTIGRALATVLDGERWIPAEAQNLPPTDSEEREVGQRLRDLTPQQFRVLQM
LGAGRLNKQIAYDLGVSEATIKAHVTAILRKLGVTNRTQAVLMAGKLAIDADGIVLPPPEED
>Mature_221_residues
TTLLIADDHPLFREALRGAVQRVMPGVELFEADNVDALYSLADAQPDADLLLMDLNMPGAQGFSALVHMRSLHPQLPVVV
VSAREEPTVMRRAIDHGAFGFIPKSADSDTIGRALATVLDGERWIPAEAQNLPPTDSEEREVGQRLRDLTPQQFRVLQML
GAGRLNKQIAYDLGVSEATIKAHVTAILRKLGVTNRTQAVLMAGKLAIDADGIVLPPPEED

Specific function: Positive activator for glycerol metabolism [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=193, Percent_Identity=27.979274611399, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789937, Length=200, Percent_Identity=25.5, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788521, Length=205, Percent_Identity=30.7317073170732, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788546, Length=197, Percent_Identity=25.8883248730964, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787473, Length=209, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1788712, Length=190, Percent_Identity=24.2105263157895, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788222, Length=198, Percent_Identity=22.2222222222222, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24144; Mature: 24013

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLIADDHPLFREALRGAVQRVMPGVELFEADNVDALYSLADAQPDADLLLMDLNMPG
CEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCEEEEECCCCC
AQGFSALVHMRSLHPQLPVVVVSAREEPTVMRRAIDHGAFGFIPKSADSDTIGRALATVL
CHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
DGERWIPAEAQNLPPTDSEEREVGQRLRDLTPQQFRVLQMLGAGRLNKQIAYDLGVSEAT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHCCCCHHH
IKAHVTAILRKLGVTNRTQAVLMAGKLAIDADGIVLPPPEED
HHHHHHHHHHHHCCCCCHHHHEEECCEEECCCCEECCCCCCC
>Mature Secondary Structure 
TTLLIADDHPLFREALRGAVQRVMPGVELFEADNVDALYSLADAQPDADLLLMDLNMPG
EEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCEEEEECCCCC
AQGFSALVHMRSLHPQLPVVVVSAREEPTVMRRAIDHGAFGFIPKSADSDTIGRALATVL
CHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
DGERWIPAEAQNLPPTDSEEREVGQRLRDLTPQQFRVLQMLGAGRLNKQIAYDLGVSEAT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHCCCCHHH
IKAHVTAILRKLGVTNRTQAVLMAGKLAIDADGIVLPPPEED
HHHHHHHHHHHHCCCCCHHHHEEECCEEECCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1938886; 10984043 [H]