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The map label for this gene is xpsE [H]

Identifier: 21244269

GI number: 21244269

Start: 4187865

End: 4189460

Strand: Reverse

Name: xpsE [H]

Synonym: XAC3544

Alternate gene names: 21244269

Gene position: 4189460-4187865 (Counterclockwise)

Preceding gene: 21244270

Following gene: 21244268

Centisome position: 80.95

GC content: 62.97

Gene sequence:

>1596_bases
ATGGGGTTGCTCGCCTTGCTCGGCCGTTTGGGTCTGGTGTCCGAACGCGATCATGCAGAAACCTGCGCCGACGTCCTTGG
CTTGCCGTTGGTGGACGCACGCCAGCTCGGCGATACGCCGCCGGAAATGCTGCCCGAAGTGCAGGGGTTGTCGCTGCGTT
TTCTCAAACAATTTCATCTGTGTCCGGTCGGCGAGCGCGATGGCCGGCTGGAGCTGTGGATCGCCGATCCTTACGACGAT
TACGCCATCGATGCAGTGCGTCTTGCCACCGGCTGCACGTTGCTGTTGCAGGTGGGCCTGCGTTCGGAAATCGATGACCT
GATCGAGCGCTGGTACGGCCAGGGCCGCAGTGCGATGGGCACCATCGTCGAAACCGCCGATGGCGATGCCAACAGTAGCG
ACGACATCGAAGCGCTGCGCGATCTGGCCTCCGAAGCGCCGGTGATCCGGCTGGTGAACCTGGTGATCCAGCACGCGGTG
GAACTGCGCGCCTCCGACATCCATATCGAACCGTTCGAAAGCCGCCTCAAGGTGCGTTACCGCGTGGACGGCGTGCTGGT
GGAAGGCGAAAGCCCGCCGGCCAAGCTCACTGCTGCGGTCATCAGCCGCATCAAGATCATGGCCAAGCTCAACATCGCCG
AGCGCCGCCTGCCGCAAGACGGCCGCATCATGCTGCGCGTGCAGGGCAAGGAGCTGGATCTGCGCGTCAGCACCGTGCCC
ACTGCGCATGGCGAAAGCGTGGTCATGCGCCTGCTCGATCGCGAGACGGTGGTGTTCGACTTCTACAAGCTCGGCTTCAC
CGAAGACTTCTTGCCGCAGTTCCGCAAGGTGCTGGAGCAACCGCACGGCACCATGCTGGTGACCGGGCCCACCGGTTCGG
GCAAGACCACCACGCTGTACACCGCGTTGAGCCAGCTCAACACCTCGGATGTGAAAATCATCACCGTCGAAGACCCGGTG
GAATACCAGATCGAAGGCATCAACCAGATCCAGGCCAAGCCGCAGATCGGGCTGGATTTCGCCAACGCATTGCGCAGCAT
CGTGCGTCAGGATCCGGACATCATCATGATCGGCGAAATGCGCGATCTGGAAACCGCACGCATCGCGATCCAGTCCGCGC
TCACCGGCCACCTGGTGCTGTCCACGCTGCACACCAATAACGCGGCCGGCGGCATCACCCGTCTGCTCGACATGGGCGTG
GAGGATTATCTGCTCACCTCCACCATCAACGGCATCCTGGCGCAGCGTCTGGTGCGCAAACTCGACCTGGCCAATGCCGA
GCGCTATGCGGCTTCGCCGGAAGAAATCGCCAAGTTCGATCTGCGCCGCCTGCAACCGGAGGGCGACATCTTTCTGTATC
GCCCGCGTCCCTCGGCCACCGCACCTACCGGGTATCTTGGACGCACCACCATCGTCGAATTCCTGGTGATGAACGACGAA
CTGCGCCGTGCGGTGATGCGCCGTGCCGGCATGGGCGAAATCGAACAACTGGCCCGCCAGGCCGGCATGCGCACCATGTA
CGAGGACGGGCTGTCCAAGGCCCTGCGTGGCGAAACCACCATCGAAGAAGTCCTGCGCGTCACGGAGGATGCGTGA

Upstream 100 bases:

>100_bases
TCGAAGTGCGGAGACGCGCATCGTCGATGCGCTGCTTGAACGCCGTCGTCTGAAAGACACCGATCTGCTGCGCGCGCGCC
AATTGCAGGCCGAATCCGGC

Downstream 100 bases:

>100_bases
TCGGTAAGGTTGCAGTAACGCGCTTAGCAGGCACTCGACCAACGACCCGCCAGCACAGCAACCCGCCGGCCCCGCTGTGC
GTGGAAAATGATACGTGCGC

Product: general secretion pathway protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MGLLALLGRLGLVSERDHAETCADVLGLPLVDARQLGDTPPEMLPEVQGLSLRFLKQFHLCPVGERDGRLELWIADPYDD
YAIDAVRLATGCTLLLQVGLRSEIDDLIERWYGQGRSAMGTIVETADGDANSSDDIEALRDLASEAPVIRLVNLVIQHAV
ELRASDIHIEPFESRLKVRYRVDGVLVEGESPPAKLTAAVISRIKIMAKLNIAERRLPQDGRIMLRVQGKELDLRVSTVP
TAHGESVVMRLLDRETVVFDFYKLGFTEDFLPQFRKVLEQPHGTMLVTGPTGSGKTTTLYTALSQLNTSDVKIITVEDPV
EYQIEGINQIQAKPQIGLDFANALRSIVRQDPDIIMIGEMRDLETARIAIQSALTGHLVLSTLHTNNAAGGITRLLDMGV
EDYLLTSTINGILAQRLVRKLDLANAERYAASPEEIAKFDLRRLQPEGDIFLYRPRPSATAPTGYLGRTTIVEFLVMNDE
LRRAVMRRAGMGEIEQLARQAGMRTMYEDGLSKALRGETTIEEVLRVTEDA

Sequences:

>Translated_531_residues
MGLLALLGRLGLVSERDHAETCADVLGLPLVDARQLGDTPPEMLPEVQGLSLRFLKQFHLCPVGERDGRLELWIADPYDD
YAIDAVRLATGCTLLLQVGLRSEIDDLIERWYGQGRSAMGTIVETADGDANSSDDIEALRDLASEAPVIRLVNLVIQHAV
ELRASDIHIEPFESRLKVRYRVDGVLVEGESPPAKLTAAVISRIKIMAKLNIAERRLPQDGRIMLRVQGKELDLRVSTVP
TAHGESVVMRLLDRETVVFDFYKLGFTEDFLPQFRKVLEQPHGTMLVTGPTGSGKTTTLYTALSQLNTSDVKIITVEDPV
EYQIEGINQIQAKPQIGLDFANALRSIVRQDPDIIMIGEMRDLETARIAIQSALTGHLVLSTLHTNNAAGGITRLLDMGV
EDYLLTSTINGILAQRLVRKLDLANAERYAASPEEIAKFDLRRLQPEGDIFLYRPRPSATAPTGYLGRTTIVEFLVMNDE
LRRAVMRRAGMGEIEQLARQAGMRTMYEDGLSKALRGETTIEEVLRVTEDA
>Mature_530_residues
GLLALLGRLGLVSERDHAETCADVLGLPLVDARQLGDTPPEMLPEVQGLSLRFLKQFHLCPVGERDGRLELWIADPYDDY
AIDAVRLATGCTLLLQVGLRSEIDDLIERWYGQGRSAMGTIVETADGDANSSDDIEALRDLASEAPVIRLVNLVIQHAVE
LRASDIHIEPFESRLKVRYRVDGVLVEGESPPAKLTAAVISRIKIMAKLNIAERRLPQDGRIMLRVQGKELDLRVSTVPT
AHGESVVMRLLDRETVVFDFYKLGFTEDFLPQFRKVLEQPHGTMLVTGPTGSGKTTTLYTALSQLNTSDVKIITVEDPVE
YQIEGINQIQAKPQIGLDFANALRSIVRQDPDIIMIGEMRDLETARIAIQSALTGHLVLSTLHTNNAAGGITRLLDMGVE
DYLLTSTINGILAQRLVRKLDLANAERYAASPEEIAKFDLRRLQPEGDIFLYRPRPSATAPTGYLGRTTIVEFLVMNDEL
RRAVMRRAGMGEIEQLARQAGMRTMYEDGLSKALRGETTIEEVLRVTEDA

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=468, Percent_Identity=42.7350427350427, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1786296, Length=387, Percent_Identity=44.1860465116279, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI87082188, Length=168, Percent_Identity=44.047619047619, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 58872; Mature: 58740

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLALLGRLGLVSERDHAETCADVLGLPLVDARQLGDTPPEMLPEVQGLSLRFLKQFHL
CCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHCCCHHHHHHHHCC
CPVGERDGRLELWIADPYDDYAIDAVRLATGCTLLLQVGLRSEIDDLIERWYGQGRSAMG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
TIVETADGDANSSDDIEALRDLASEAPVIRLVNLVIQHAVELRASDIHIEPFESRLKVRY
HEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEE
RVDGVLVEGESPPAKLTAAVISRIKIMAKLNIAERRLPQDGRIMLRVQGKELDLRVSTVP
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEECCEEEEEEEECC
TAHGESVVMRLLDRETVVFDFYKLGFTEDFLPQFRKVLEQPHGTMLVTGPTGSGKTTTLY
CCCCHHHHHHHHCCCHHEEHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHH
TALSQLNTSDVKIITVEDPVEYQIEGINQIQAKPQIGLDFANALRSIVRQDPDIIMIGEM
HHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
RDLETARIAIQSALTGHLVLSTLHTNNAAGGITRLLDMGVEDYLLTSTINGILAQRLVRK
CCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LDLANAERYAASPEEIAKFDLRRLQPEGDIFLYRPRPSATAPTGYLGRTTIVEFLVMNDE
HHHCCCHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHH
LRRAVMRRAGMGEIEQLARQAGMRTMYEDGLSKALRGETTIEEVLRVTEDA
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
GLLALLGRLGLVSERDHAETCADVLGLPLVDARQLGDTPPEMLPEVQGLSLRFLKQFHL
CHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHCCCHHHHHHHHCC
CPVGERDGRLELWIADPYDDYAIDAVRLATGCTLLLQVGLRSEIDDLIERWYGQGRSAMG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
TIVETADGDANSSDDIEALRDLASEAPVIRLVNLVIQHAVELRASDIHIEPFESRLKVRY
HEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEE
RVDGVLVEGESPPAKLTAAVISRIKIMAKLNIAERRLPQDGRIMLRVQGKELDLRVSTVP
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEECCEEEEEEEECC
TAHGESVVMRLLDRETVVFDFYKLGFTEDFLPQFRKVLEQPHGTMLVTGPTGSGKTTTLY
CCCCHHHHHHHHCCCHHEEHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHH
TALSQLNTSDVKIITVEDPVEYQIEGINQIQAKPQIGLDFANALRSIVRQDPDIIMIGEM
HHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
RDLETARIAIQSALTGHLVLSTLHTNNAAGGITRLLDMGVEDYLLTSTINGILAQRLVRK
CCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LDLANAERYAASPEEIAKFDLRRLQPEGDIFLYRPRPSATAPTGYLGRTTIVEFLVMNDE
HHHCCCHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHH
LRRAVMRRAGMGEIEQLARQAGMRTMYEDGLSKALRGETTIEEVLRVTEDA
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1944223; 12024217 [H]