Click here to switch to the map view.

The map label for this gene is 21244270

Identifier: 21244270

GI number: 21244270

Start: 4189722

End: 4191605

Strand: Reverse

Name: 21244270

Synonym: XAC3545

Alternate gene names: NA

Gene position: 4191605-4189722 (Counterclockwise)

Preceding gene: 21244271

Following gene: 21244269

Centisome position: 80.99

GC content: 67.73

Gene sequence:

>1884_bases
GTGATCGACAAGAATTTCCGTCTCAACCCGCTGACCGGCGCCATCCTGATGATGGCCCTCGGTGCGTCTGGCACGTTGGC
TGCCGCCCCCAAACTGCTGGTCAAGGAACCGACCCAGGCAGCCCCGGCCGGCGCAGCGTTCGGTAGCCGGTTGATCGTGC
GCTACAAGGACAGCACCGCCGCTGCGACCGATCGCAGCAGCAAGCTGAGCGCCGTGCAGGCCGCGGTGGGCCGCGTTGGC
GTCGGTACTGGCGCGCGCAGCAGCGCTGCCGCCGCCAAGGCCACGTATGTGCGCAAGCTGGGCATCGGCTCGGACCTGAT
CAAGCTGTCGAGCACGCTGACCGCCGCGCAGGTGGACAAGGTGGTGGTCGAGCTCAAGAACGACCCATCCGTGGCCGACG
TGCAGATCGACCGCATGCTGCGCCCGATCGACATCAGCAAGAGCGTTCCTGCCACCGACGTGAGCCCGCAGCTGGTTCCC
AACGACCCGCTGTACGCCCAGTACCAGTGGCACCTGAGCAACCCCAATGGCGGCATCAATGCACCGGCTGCATGGGATCT
GTCGCAGGGCGCAGGCGTGGTGGTCGCGGTACTGGATACCGGCATCCTGCCGGGCCATCCGGATTTCGCCGGCAACATCC
TGCAGGGCTACGACTTCATCACCGACGCCGAAGTCTCGCGTCGTCCCACCGATGCGCGCGTGCCGGGCGCACTCGATTAT
GGCGACTGGGAAGAGGCCGACAACGTCTGCTACGCGGGCTCACAGGCGCAGGAAAGTTCCTGGCACGGCACCCATGTCTC
GGGCACCGTGGCCGAGGCGACCAATAACGGCGTGGGCATGGCAGGCGTCGCGCCGAAGGCGACCATCCTGCCGGTGCGCG
TGCTCGGTCGTTGCGGCGGCTACACCTCCGACATCGCCGATGCGATCGTGTGGGCCTCCGGCGGCAGCGTCGACGGCGTG
CCGGCCAACAGCAATCCGGCCGAAGTGATCAACATGAGCCTCGGTGGCGGCGAACCCTGCGATTCGGCCACCCAGCTGGC
GATCAACAGCGCGGTGTCGCGCGGCACCACCGTGGTGGTTGCAGCCGGCAACAGCAGCGAAGATGCAGCCAACCATTCGC
CGGCCAGCTGCAACAACACCATCACCGTTGGCGCCACGCGCATCACCGGCGGCATCGCCTACTACTCCAACTACGGCAGC
AAGGTCGACCTCTCTGGACCGGGCGGCGGCGGTAGCGTGGACGGCAACCCGGGCGGTTACATCTGGCAGGCCGGCTACAC
CGGTGCGACCACGCCGACCTCGGGTAGCTATACCTATATGGGGCTAGGCGGCACCTCGATGGCCTCGCCGCACGTGGCTG
GCGTCGTGGCGCTGGTGCAGAGCGCAGCCATCGGGCTGGGCGATGGCCCGCTGACCCCGGCCGCGGTCGAAGCCCTGCTC
AAGCAGACCAGCCGCCGCTTCCCGGTGACCCCGCCGGCCAGCACCCCGATCGGCAGCGGCATCGTCGACGCCAAGGCCGC
GCTGGAAGCCGTGCTTGAGGAGCCGTGCGACCCGGCCACCGAGAGCTGCGCGCCGAGCGCCATCGAGCTCACCAACAAGG
CACCTGTTGCTGGCTTGAGCGGTGCCGCCGGCGGCTCCACGCTATACAGCTTCGAGGCCAAGGCCGGCGCCGTGCTCAGC
TTCATGACCTACGGCGGCACCGGCGATGTGTCGATGTACGTCAGCTTTGAGGCCGAGCCCAGCGCAACCAGCTACGACGC
CAAGTCGACCCGTCCGGGCAACAGCGAAACCGTGCGTTTCACTGCCCCCAAGGCCGGCACCTACTACATCAAGTTGGTCG
GCGCGGCGAGCTACGCGAAGCTGACGCTCGTTGCACGACAGTGA

Upstream 100 bases:

>100_bases
GGGTAGCCGGCAAGGACGCAGCGCACCGCACCGCGGCTACGCAGCGATTGCGCCGGCTGCGCCAAGCCTGATTCACGAAA
AATACGAAGAGGACTTCACC

Downstream 100 bases:

>100_bases
GTAGCGAAATAGTGTGACCGATGCCCCCGGCCAATCGCCGGGGGCATTGTTTTTCAGGGCGATTCAGATGCGTGCGGTTG
ATCGTCGCGGCAAACTGCTA

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDSTAAATDRSSKLSAVQAAVGRVG
VGTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDKVVVELKNDPSVADVQIDRMLRPIDISKSVPATDVSPQLVP
NDPLYAQYQWHLSNPNGGINAPAAWDLSQGAGVVVAVLDTGILPGHPDFAGNILQGYDFITDAEVSRRPTDARVPGALDY
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGGYTSDIADAIVWASGGSVDGV
PANSNPAEVINMSLGGGEPCDSATQLAINSAVSRGTTVVVAAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNYGS
KVDLSGPGGGGSVDGNPGGYIWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
KQTSRRFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIELTNKAPVAGLSGAAGGSTLYSFEAKAGAVLS
FMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRFTAPKAGTYYIKLVGAASYAKLTLVARQ

Sequences:

>Translated_627_residues
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDSTAAATDRSSKLSAVQAAVGRVG
VGTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDKVVVELKNDPSVADVQIDRMLRPIDISKSVPATDVSPQLVP
NDPLYAQYQWHLSNPNGGINAPAAWDLSQGAGVVVAVLDTGILPGHPDFAGNILQGYDFITDAEVSRRPTDARVPGALDY
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGGYTSDIADAIVWASGGSVDGV
PANSNPAEVINMSLGGGEPCDSATQLAINSAVSRGTTVVVAAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNYGS
KVDLSGPGGGGSVDGNPGGYIWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
KQTSRRFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIELTNKAPVAGLSGAAGGSTLYSFEAKAGAVLS
FMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRFTAPKAGTYYIKLVGAASYAKLTLVARQ
>Mature_627_residues
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDSTAAATDRSSKLSAVQAAVGRVG
VGTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDKVVVELKNDPSVADVQIDRMLRPIDISKSVPATDVSPQLVP
NDPLYAQYQWHLSNPNGGINAPAAWDLSQGAGVVVAVLDTGILPGHPDFAGNILQGYDFITDAEVSRRPTDARVPGALDY
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGGYTSDIADAIVWASGGSVDGV
PANSNPAEVINMSLGGGEPCDSATQLAINSAVSRGTTVVVAAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNYGS
KVDLSGPGGGGSVDGNPGGYIWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
KQTSRRFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIELTNKAPVAGLSGAAGGSTLYSFEAKAGAVLS
FMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRFTAPKAGTYYIKLVGAASYAKLTLVARQ

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=337, Percent_Identity=29.673590504451, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324576, Length=341, Percent_Identity=28.1524926686217, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319893, Length=281, Percent_Identity=29.1814946619217, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 63397; Mature: 63397

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDSTA
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCHHEECCCCCCCCCCCCCCCEEEEEECCCCC
AATDRSSKLSAVQAAVGRVGVGTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDK
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCE
VVVELKNDPSVADVQIDRMLRPIDISKSVPATDVSPQLVPNDPLYAQYQWHLSNPNGGIN
EEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCC
APAAWDLSQGAGVVVAVLDTGILPGHPDFAGNILQGYDFITDAEVSRRPTDARVPGALDY
CCCCEECCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCEECCHHHCCCCCCCCCCCCCC
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGG
CCCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCEEEHHHHHHHCCC
YTSDIADAIVWASGGSVDGVPANSNPAEVINMSLGGGEPCDSATQLAINSAVSRGTTVVV
CHHHHHHHEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEE
AAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNYGSKVDLSGPGGGGSVDGNPGGY
ECCCCCCCCCCCCCCCCCCEEEEEEEEHHCCEEEEECCCCEEEECCCCCCCCCCCCCCCE
IWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
EEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KQTSRRFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIELTNKAPVAGLS
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCCC
GAAGGSTLYSFEAKAGAVLSFMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRF
CCCCCCEEEEECCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEE
TAPKAGTYYIKLVGAASYAKLTLVARQ
ECCCCCEEEEEEEECCCEEEEEEEECC
>Mature Secondary Structure
MIDKNFRLNPLTGAILMMALGASGTLAAAPKLLVKEPTQAAPAGAAFGSRLIVRYKDSTA
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCHHEECCCCCCCCCCCCCCCEEEEEECCCCC
AATDRSSKLSAVQAAVGRVGVGTGARSSAAAAKATYVRKLGIGSDLIKLSSTLTAAQVDK
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCE
VVVELKNDPSVADVQIDRMLRPIDISKSVPATDVSPQLVPNDPLYAQYQWHLSNPNGGIN
EEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCC
APAAWDLSQGAGVVVAVLDTGILPGHPDFAGNILQGYDFITDAEVSRRPTDARVPGALDY
CCCCEECCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCEECCHHHCCCCCCCCCCCCCC
GDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATNNGVGMAGVAPKATILPVRVLGRCGG
CCCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCEEEHHHHHHHCCC
YTSDIADAIVWASGGSVDGVPANSNPAEVINMSLGGGEPCDSATQLAINSAVSRGTTVVV
CHHHHHHHEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEE
AAGNSSEDAANHSPASCNNTITVGATRITGGIAYYSNYGSKVDLSGPGGGGSVDGNPGGY
ECCCCCCCCCCCCCCCCCCEEEEEEEEHHCCEEEEECCCCEEEECCCCCCCCCCCCCCCE
IWQAGYTGATTPTSGSYTYMGLGGTSMASPHVAGVVALVQSAAIGLGDGPLTPAAVEALL
EEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KQTSRRFPVTPPASTPIGSGIVDAKAALEAVLEEPCDPATESCAPSAIELTNKAPVAGLS
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCCC
GAAGGSTLYSFEAKAGAVLSFMTYGGTGDVSMYVSFEAEPSATSYDAKSTRPGNSETVRF
CCCCCCEEEEECCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEE
TAPKAGTYYIKLVGAASYAKLTLVARQ
ECCCCCEEEEEEEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]