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The map label for this gene is tctE [H]

Identifier: 21244207

GI number: 21244207

Start: 4114577

End: 4115962

Strand: Reverse

Name: tctE [H]

Synonym: XAC3482

Alternate gene names: 21244207

Gene position: 4115962-4114577 (Counterclockwise)

Preceding gene: 21244208

Following gene: 77748719

Centisome position: 79.53

GC content: 68.11

Gene sequence:

>1386_bases
ATGGCTGAGCCGCTGACGGTGGCACCGTCGATCCGGCGCACCTTGCTGCTGTATCTGGGCAGCCTGTCGCTGCTGGGTGC
GGTGGTGCTGTTCTTTGCCGCACGCGATTACGGCCAGCGTGCGGCCAATCGGTCCTACGATCACCTGCTGGTGTCCTCGG
CCCTGTCGATCATCGACAGCGTGGCGTTGGTCGGCGGCGACTGGCAGGTGGATCTGCCGTACGCCTCGCTGGATCTGCTC
GGCATGGCGCCGGAGGACCGCGTGTTCTATCGCGTGTTCGATGCGCAGGGCCGCACCATCACTGGCGAAGACACGCTGCC
GCTGCCGCCGCGTGCGCCGCGCGACGAGCGGCCGCTGTTGTTCGATGCGCAGTACAGCGGCGAGCCGGTGCGCTTTGCGG
TGGTGATGCATCGGGTGGCGTCGGCGTCTGGGCAGGGCGAGGTGCGCGTGCAGGTGGGCCAGACCCGGCGCGCACGCGAT
GCGGTGGCGCGCGATGTGGTGCTCAACGCCTTGGTCGCGATCGGCGTGCTGTCGCTGCTGGCGCTGGGCCTGGTGTGGCT
GGGCGTCTATCGCGCGTTGCGGCCGCTGCAGCGCATCGAGGGCGATCTGTCGCGGCGCGAGCCCTCCGACCTCAAGCCGC
TGAACGTGCCGGCGCCGCAGGAAATGCAGTTGATGGTGACCGCGCTCAACCGGTTCATGGCGCGGCTTTCGTCCAGCAAC
GAAACCTTGCGCGCCTTCATGGCCGAGGCCGCGCACCAGATGCGCACGCCGCTGGCGGCCTTGCGCGCGCAGGCGCAGCT
GGCGATGGACGACGACGACCCGCGCGAGATGCAACGCAGCCTGGTGGCGATCGAGCGCAACGCCAGCCACATGAGCCGGT
TGCTCAATCAGTTGCTCAGCGATGCCAGCGTGATCCATCGTGCCAACCTGCAGCGCTTTGCCACCGTGGATCTGGCCGAG
GTGTTGCATCAGGCCTTGCACGAAGCGCTGCCGCGCAGCCCAGGCGCACCGCGCGTGCAGCTGGCGATCGACCCGCAACC
GGCGCTGCTGCGTGGCGATGCCTTGCTGCTACGCGAGGCGCTGAAAAACCTGATCGACAACGCATGCAAATACGGTGCCG
GTGCCTCGCTGCAGGTGGCGCTCACCAGCGACGGCAACCATCACGTACTGACCATTGCCGATCATGGCCCCGGCATTCCC
GCAGCCGAAGCCGAGCGTGTGTTCGAGCGTTTCGTACGTGGGGCGGATGCGCCGGTCGGCGGCGCCGGTCTGGGGTTGGC
CATCGTCAAGCGCGTGGTGGAAGCGCATGGCGGGCGCATCGATCTGGCCAACCGCATCGGTGGCGGCTTGATCGCCTCGA
TGCATTTTCCGGGAGGAGGGGCGTGA

Upstream 100 bases:

>100_bases
CGCAAACTGGCCGCCGCGCCGTTGCGTATCGTCACCGTGCGCGGTGCCGGTTACAAACTCGAAGAAGCCGACCCGCATGC
GCCGATGGAGCCGGGCGTCG

Downstream 100 bases:

>100_bases
TGCGGCCGATGTGGATGCTGGTGTTGCTGCTGGTCCATGGCATCGCCTGCGCGGCGCCAGGCGATGTGCGTCGCTTTCCC
GCACAGGGCCCGGTGCGTGT

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MAEPLTVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGQRAANRSYDHLLVSSALSIIDSVALVGGDWQVDLPYASLDLL
GMAPEDRVFYRVFDAQGRTITGEDTLPLPPRAPRDERPLLFDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARD
AVARDVVLNALVAIGVLSLLALGLVWLGVYRALRPLQRIEGDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPREMQRSLVAIERNASHMSRLLNQLLSDASVIHRANLQRFATVDLAE
VLHQALHEALPRSPGAPRVQLAIDPQPALLRGDALLLREALKNLIDNACKYGAGASLQVALTSDGNHHVLTIADHGPGIP
AAEAERVFERFVRGADAPVGGAGLGLAIVKRVVEAHGGRIDLANRIGGGLIASMHFPGGGA

Sequences:

>Translated_461_residues
MAEPLTVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGQRAANRSYDHLLVSSALSIIDSVALVGGDWQVDLPYASLDLL
GMAPEDRVFYRVFDAQGRTITGEDTLPLPPRAPRDERPLLFDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARD
AVARDVVLNALVAIGVLSLLALGLVWLGVYRALRPLQRIEGDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPREMQRSLVAIERNASHMSRLLNQLLSDASVIHRANLQRFATVDLAE
VLHQALHEALPRSPGAPRVQLAIDPQPALLRGDALLLREALKNLIDNACKYGAGASLQVALTSDGNHHVLTIADHGPGIP
AAEAERVFERFVRGADAPVGGAGLGLAIVKRVVEAHGGRIDLANRIGGGLIASMHFPGGGA
>Mature_460_residues
AEPLTVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGQRAANRSYDHLLVSSALSIIDSVALVGGDWQVDLPYASLDLLG
MAPEDRVFYRVFDAQGRTITGEDTLPLPPRAPRDERPLLFDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARDA
VARDVVLNALVAIGVLSLLALGLVWLGVYRALRPLQRIEGDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSNE
TLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPREMQRSLVAIERNASHMSRLLNQLLSDASVIHRANLQRFATVDLAEV
LHQALHEALPRSPGAPRVQLAIDPQPALLRGDALLLREALKNLIDNACKYGAGASLQVALTSDGNHHVLTIADHGPGIPA
AEAERVFERFVRGADAPVGGAGLGLAIVKRVVEAHGGRIDLANRIGGGLIASMHFPGGGA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=386, Percent_Identity=30.0518134715026, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790551, Length=296, Percent_Identity=31.0810810810811, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786912, Length=273, Percent_Identity=32.967032967033, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=27.8388278388278, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787374, Length=292, Percent_Identity=26.7123287671233, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=26.4214046822742, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786783, Length=288, Percent_Identity=26.7361111111111, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=25.9515570934256, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=295, Percent_Identity=27.7966101694915, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=29.7959183673469, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=28.0701754385965, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=211, Percent_Identity=31.7535545023697, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=30.6666666666667, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87081816, Length=332, Percent_Identity=27.1084337349398, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=25.5144032921811, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=25.7936507936508, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=26.1261261261261, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=297, Percent_Identity=25.2525252525253, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788713, Length=222, Percent_Identity=23.8738738738739, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=26.5116279069767, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49717; Mature: 49586

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPLTVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGQRAANRSYDHLLVSSALSIIDS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VALVGGDWQVDLPYASLDLLGMAPEDRVFYRVFDAQGRTITGEDTLPLPPRAPRDERPLL
HHHCCCCEEEECCCHHHHHCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCEE
FDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARDAVARDVVLNALVAIGVLSLL
EECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLVWLGVYRALRPLQRIEGDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCH
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPREMQRSLVAIERNASHMSRLLNQLLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
DASVIHRANLQRFATVDLAEVLHQALHEALPRSPGAPRVQLAIDPQPALLRGDALLLREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHCCHHHHHHHH
LKNLIDNACKYGAGASLQVALTSDGNHHVLTIADHGPGIPAAEAERVFERFVRGADAPVG
HHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GAGLGLAIVKRVVEAHGGRIDLANRIGGGLIASMHFPGGGA
CCHHHHHHHHHHHHHCCCEEEEHHHCCCCEEEEEECCCCCC
>Mature Secondary Structure 
AEPLTVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGQRAANRSYDHLLVSSALSIIDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VALVGGDWQVDLPYASLDLLGMAPEDRVFYRVFDAQGRTITGEDTLPLPPRAPRDERPLL
HHHCCCCEEEECCCHHHHHCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCEE
FDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARDAVARDVVLNALVAIGVLSLL
EECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLVWLGVYRALRPLQRIEGDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCH
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPREMQRSLVAIERNASHMSRLLNQLLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
DASVIHRANLQRFATVDLAEVLHQALHEALPRSPGAPRVQLAIDPQPALLRGDALLLREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHCCHHHHHHHH
LKNLIDNACKYGAGASLQVALTSDGNHHVLTIADHGPGIPAAEAERVFERFVRGADAPVG
HHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GAGLGLAIVKRVVEAHGGRIDLANRIGGGLIASMHFPGGGA
CCHHHHHHHHHHHHHCCCEEEEHHHCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]