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The map label for this gene is tctD [H]

Identifier: 21244208

GI number: 21244208

Start: 4115955

End: 4116656

Strand: Reverse

Name: tctD [H]

Synonym: XAC3483

Alternate gene names: 21244208

Gene position: 4116656-4115955 (Counterclockwise)

Preceding gene: 21244213

Following gene: 21244207

Centisome position: 79.54

GC content: 64.81

Gene sequence:

>702_bases
ATGCGCCTTCTGCTAGTCGAAGACAATGCCGACCTCGCCGATGCCATCGTGCGGCGCATGCGCCGTAGCGGGCATGCGGT
GGATTGGCAGGCCGATGGGTTGGCGGCGGCGAGTGTGTTGCGGTATCAGAGCTTCGATCTGGTGGTGCTGGATATCGGTT
TGCCCAAACTCGATGGACTGCGGGTGCTGGCCGGCATGCGCGAGCGGGGCGATGCCACGCCGGTGCTGATGCTGACCGCG
CGCGATGGCATCGAAGACCGCGTGCAGGCGTTGGATGTCGGTGCGGACGATTACCTGGGCAAGCCGTTCGACTTCCGGGA
GTTCGAAGCGCGTTGCCGCGTATTGCTGCGGCGTAATCGGGGCCAGGCCAGCGAGGTGGTGCAGATCGGTGGATTCGTCT
TCGACAATGCCGCGCACACGCTGCTGCTGGATGGCGTGCCGATCGAGTTGCCCAATCGCGAATATCGCCTGTTTGAAATC
CTGATCGGACGGCTCGGGCAGGTGGTTGGCAAGGACGAGATCGGCAACGGGTTGTTCGGCTTCGACGACGACGCCGGGCC
CAACGCGATCGAGCTGTATGTCGGCCGGCTGCGGCGCAAACTGGCCGCCGCGCCGTTGCGTATCGTCACCGTGCGCGGTG
CCGGTTACAAACTCGAAGAAGCCGACCCGCATGCGCCGATGGAGCCGGGCGTCGATGGCTGA

Upstream 100 bases:

>100_bases
TGCCGAGGTGTAGAAGCTTTTGTTCTCTGGGCCTGTTACCTTCCGGCCGCGGCCCAGCGCCGTTGCGATTCCCCATTCCC
TATTCACGATTCCCCACCCA

Downstream 100 bases:

>100_bases
GCCGCTGACGGTGGCACCGTCGATCCGGCGCACCTTGCTGCTGTATCTGGGCAGCCTGTCGCTGCTGGGTGCGGTGGTGC
TGTTCTTTGCCGCACGCGAT

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRLLLVEDNADLADAIVRRMRRSGHAVDWQADGLAAASVLRYQSFDLVVLDIGLPKLDGLRVLAGMRERGDATPVLMLTA
RDGIEDRVQALDVGADDYLGKPFDFREFEARCRVLLRRNRGQASEVVQIGGFVFDNAAHTLLLDGVPIELPNREYRLFEI
LIGRLGQVVGKDEIGNGLFGFDDDAGPNAIELYVGRLRRKLAAAPLRIVTVRGAGYKLEEADPHAPMEPGVDG

Sequences:

>Translated_233_residues
MRLLLVEDNADLADAIVRRMRRSGHAVDWQADGLAAASVLRYQSFDLVVLDIGLPKLDGLRVLAGMRERGDATPVLMLTA
RDGIEDRVQALDVGADDYLGKPFDFREFEARCRVLLRRNRGQASEVVQIGGFVFDNAAHTLLLDGVPIELPNREYRLFEI
LIGRLGQVVGKDEIGNGLFGFDDDAGPNAIELYVGRLRRKLAAAPLRIVTVRGAGYKLEEADPHAPMEPGVDG
>Mature_233_residues
MRLLLVEDNADLADAIVRRMRRSGHAVDWQADGLAAASVLRYQSFDLVVLDIGLPKLDGLRVLAGMRERGDATPVLMLTA
RDGIEDRVQALDVGADDYLGKPFDFREFEARCRVLLRRNRGQASEVVQIGGFVFDNAAHTLLLDGVPIELPNREYRLFEI
LIGRLGQVVGKDEIGNGLFGFDDDAGPNAIELYVGRLRRKLAAAPLRIVTVRGAGYKLEEADPHAPMEPGVDG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=40, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=37.1559633027523, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=34.0909090909091, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=38.0090497737557, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.5555555555556, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.3891402714932, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=30.6666666666667, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=184, Percent_Identity=35.8695652173913, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=29.2792792792793, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=34.4827586206897, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=29.0178571428571, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.4932735426009, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=27.9475982532751, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790437, Length=154, Percent_Identity=29.8701298701299, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787487, Length=115, Percent_Identity=33.0434782608696, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=34.9514563106796, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25618; Mature: 25618

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLVEDNADLADAIVRRMRRSGHAVDWQADGLAAASVLRYQSFDLVVLDIGLPKLDGL
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCH
RVLAGMRERGDATPVLMLTARDGIEDRVQALDVGADDYLGKPFDFREFEARCRVLLRRNR
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCC
GQASEVVQIGGFVFDNAAHTLLLDGVPIELPNREYRLFEILIGRLGQVVGKDEIGNGLFG
CCHHHHHHHCCEEECCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHCHHHCCCCCCC
FDDDAGPNAIELYVGRLRRKLAAAPLRIVTVRGAGYKLEEADPHAPMEPGVDG
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLLLVEDNADLADAIVRRMRRSGHAVDWQADGLAAASVLRYQSFDLVVLDIGLPKLDGL
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCH
RVLAGMRERGDATPVLMLTARDGIEDRVQALDVGADDYLGKPFDFREFEARCRVLLRRNR
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCC
GQASEVVQIGGFVFDNAAHTLLLDGVPIELPNREYRLFEILIGRLGQVVGKDEIGNGLFG
CCHHHHHHHCCEEECCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHCHHHCCCCCCC
FDDDAGPNAIELYVGRLRRKLAAAPLRIVTVRGAGYKLEEADPHAPMEPGVDG
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]