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The map label for this gene is prc [H]

Identifier: 21241440

GI number: 21241440

Start: 793114

End: 795297

Strand: Direct

Name: prc [H]

Synonym: XAC0669

Alternate gene names: 21241440

Gene position: 793114-795297 (Clockwise)

Preceding gene: 21241439

Following gene: 21241442

Centisome position: 15.32

GC content: 64.1

Gene sequence:

>2184_bases
ATGACCTACAACGTTTCTTCGTGCATGAAGGCCGGCCTGCTGGCGCTGGTGTTGACCACTCCGATGGCCTTGCTCGCACG
CGCCGATACTGCGCTGCCGGCCGCTGCCACGCCCGATCAGGCGACGGCCACCAAACTCGTGTACGGCCTGCTCTCCGACA
GCCGCTATGCCTACCGGCCGCGCACGCTGGACGAGGCGATGTCCAAGGACGTGTTCAAGCGCTATCTGGAAACGCTGGAT
GGCGGCAAACAGTTCTTCACCCAGGCCGATATCGACAGCTTCGCGCCCCTCCAGGCCGGTGTTGGCGACGCGTTGCGCGG
CGGCAACCTGGAGCCGGCGTTCAAGGTGTTCTCGGTCTACAAGAAGCGCGTCGATCAGCGCGTCAAGTACGCGCGCGACC
TGCTCAAGCAGGACTTCGATTTCAGCGGTAACGACAAGTTCGAGTACGACCGCAAGGACGTGCCGTGGGCTGCGGACGAC
AAGCAGTTGGACGTGCTGTGGCGCCAGTCGGTGATGAACGATTGGCTGCGCCTGAAACTGGCCGGCAAGAAGCCCGACGA
CATCCGCAAGACGCTGGACAAGCGGTATGTGGCGCTGGCCGATTCGGTCAAGCAGCTCAAGGGCGAAGACGTGTTCCAGT
TCTTCGTCAACGCCTACACCAACGCCGTCGACCCGCACACCGATTACTTCACCCCGCGCACGGCCGAGACGTTCAACCAG
CAGATGTCGCTGTCGTTGGAAGGCATTGGCGCGCAGCTGCAGAAACAGGACGACATGGTGGTGATCCGCGAGGTGATCCC
GGGCGGTCCGGCGGCGGTGGATGGCACGCTCAAGCCGGGCGATCGCATCGTCGGCGTTGGGCAGGCCAAGAGTGGCGCGA
TCGAAGATGTGATCGGCTGGCGCATCGACGACGTGGTGGCCAAGATCCGCGGCAGCAAGGATACCCAGGTGCGCCTGGAG
TACATCCCGGCCGAGTCGGGCATCGATGGCAAGCACCGCACGGTGACCCTGACCCGTCAGAAGGTGCGTCTGGCCGAGCA
GGCTGCCAAGGGCGAAACCATCACCTTGCCGGCCACCGGCAGCGAGCCGCAGCGCCGCATCGGCATCATCAAGCTGCCGG
GCTTCTACCAGGATTTCGAAGGCCGCCGTCGCAATGCAGCCGACTACGCCTCGGCCACGCGCGACGTCGCCAAGCTGCTG
GCCGGCTTCAAGACCGACAAGGTCGATGGCGTGGTGCTGGACCTGCGCAATAACGGCGGTGGTTCGCTCGACGAGGCGAT
CGAACTGACCGGCTTGTTCATCGAGCAGGGGCCGGTCGTGCAGGTCCGCGAATCCGGCGGCCGCGTCACCGTCAATGGCG
ACAGCGACCCCAAGGTCGCCTGGGACGGCCCGCTGGCTGTCTTGATCAACCGCGGCTCGGCGTCGGCATCGGAGATCTTT
GCCGGTGCGATCCAGGATTACGGCCGCGGTCTGGTGATCGGCGAAACCAGCTTCGGCAAGGGCACCGTGCAGAACATCGT
CGACCTGGATCGCTGGCCTGCTGCCGAAGGGCAGCGGTATGGGCAGGTCAAGCTGACGATCGCGCAGTTCTTCCGCGTCA
GCGGCTCCAGCACCCAGCACAAGGGTGTGGTGCCGGATATCGCCTTCCCGGCCAGCGTGGATGCCACCGAGTTCGGTGAG
AGCACCTACGACAATGCATTGCCGTGGACGCGTATCGCCGCTGCCCCGCATACCCAGTACGGCAACTTCGCGGCATTGCT
GCCCAAGTTGCAGGCTCTGCACACTGCGCGGATTGCCAGCGACAAGGAGTTCCAGTGGTGGGAAGAAGACGTCAAGCAGT
TCCGCGACGAAAAGGCCAAGAAGTACATTTCGTTGAATGAGGCCGAGCGCGTTGCCGAGCGACAGAAGCAGGATCAGCAG
CGCAAGGATCGCCAGCAGATTCGCAAGCAACTCGGCCTGCCGCTGGATCCGCTTGCCGAAGACAGCGACGACGGCCTGAC
CGGTAACGAGCGCGACATCGTCAAGGACACTGCACGCGAAAAAGCGGCCGAAAAGCGCCCGGATCCGTTGCTGCATGAAT
CGGCGGCCATCCTTGCGGATGCGCTGGGCTTGCTGTCGCAGGACAAGCCCTTGTCGGCGCAGGTGCTGCCGAAGTCGACC
TCCCCGGGACGTTGGGCAGACTGA

Upstream 100 bases:

>100_bases
TTCAGCCAGCGGATGACAACGCCAGCAACTTTCGGCACTGTCATGCTGTCTGATCCGTTCACCGCCTCTCTTTCATCGGC
CCCGTGCCGAGAGCCATTCG

Downstream 100 bases:

>100_bases
GCCACGCTGCCGATCGACTGCATGGACGCCACCGCTTGCCGGTGGCGTTTTCATGTTGGCAATACCGTGGCCGCTGGCAG
CGTCTCAGGCGACCGCCTGC

Product: tail-specific protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MTYNVSSCMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRPRTLDEAMSKDVFKRYLETLD
GGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFKVFSVYKKRVDQRVKYARDLLKQDFDFSGNDKFEYDRKDVPWAADD
KQLDVLWRQSVMNDWLRLKLAGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQAKSGAIEDVIGWRIDDVVAKIRGSKDTQVRLE
YIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATGSEPQRRIGIIKLPGFYQDFEGRRRNAADYASATRDVAKLL
AGFKTDKVDGVVLDLRNNGGGSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLAVLINRGSASASEIF
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQHKGVVPDIAFPASVDATEFGE
STYDNALPWTRIAAAPHTQYGNFAALLPKLQALHTARIASDKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQ
RKDRQQIRKQLGLPLDPLAEDSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
SPGRWAD

Sequences:

>Translated_727_residues
MTYNVSSCMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRPRTLDEAMSKDVFKRYLETLD
GGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFKVFSVYKKRVDQRVKYARDLLKQDFDFSGNDKFEYDRKDVPWAADD
KQLDVLWRQSVMNDWLRLKLAGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQAKSGAIEDVIGWRIDDVVAKIRGSKDTQVRLE
YIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATGSEPQRRIGIIKLPGFYQDFEGRRRNAADYASATRDVAKLL
AGFKTDKVDGVVLDLRNNGGGSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLAVLINRGSASASEIF
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQHKGVVPDIAFPASVDATEFGE
STYDNALPWTRIAAAPHTQYGNFAALLPKLQALHTARIASDKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQ
RKDRQQIRKQLGLPLDPLAEDSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
SPGRWAD
>Mature_726_residues
TYNVSSCMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRPRTLDEAMSKDVFKRYLETLDG
GKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFKVFSVYKKRVDQRVKYARDLLKQDFDFSGNDKFEYDRKDVPWAADDK
QLDVLWRQSVMNDWLRLKLAGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQQ
MSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQAKSGAIEDVIGWRIDDVVAKIRGSKDTQVRLEY
IPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATGSEPQRRIGIIKLPGFYQDFEGRRRNAADYASATRDVAKLLA
GFKTDKVDGVVLDLRNNGGGSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLAVLINRGSASASEIFA
GAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQHKGVVPDIAFPASVDATEFGES
TYDNALPWTRIAAAPHTQYGNFAALLPKLQALHTARIASDKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQR
KDRQQIRKQLGLPLDPLAEDSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKSTS
PGRWAD

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=716, Percent_Identity=41.340782122905, Blast_Score=489, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 80068; Mature: 79937

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYNVSSCMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECC
RTLDEAMSKDVFKRYLETLDGGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFKVFSVY
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHH
KKRVDQRVKYARDLLKQDFDFSGNDKFEYDRKDVPWAADDKQLDVLWRQSVMNDWLRLKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
AGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQAKSGAIEDVIGW
HHEEEHHCCCCHHHCCCCEEEEEHHCCCCCCEECCCCCCCCEEEEECCCCCCCHHHHHHH
RIDDVVAKIRGSKDTQVRLEYIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATG
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCEEEECCCC
SEPQRRIGIIKLPGFYQDFEGRRRNAADYASATRDVAKLLAGFKTDKVDGVVLDLRNNGG
CCHHHCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
GSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLAVLINRGSASASEIF
CCHHHHHHHHHEEECCCCEEEEECCCCEEEECCCCCCCEEECCCEEEEEECCCCCHHHHH
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQH
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCCC
KGVVPDIAFPASVDATEFGESTYDNALPWTRIAAAPHTQYGNFAALLPKLQALHTARIAS
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHCC
DKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQRKDRQQIRKQLGLPLDPLAE
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCC
SPGRWAD
CCCCCCC
>Mature Secondary Structure 
TYNVSSCMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECC
RTLDEAMSKDVFKRYLETLDGGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFKVFSVY
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHH
KKRVDQRVKYARDLLKQDFDFSGNDKFEYDRKDVPWAADDKQLDVLWRQSVMNDWLRLKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
AGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQAKSGAIEDVIGW
HHEEEHHCCCCHHHCCCCEEEEEHHCCCCCCEECCCCCCCCEEEEECCCCCCCHHHHHHH
RIDDVVAKIRGSKDTQVRLEYIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATG
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCEEEECCCC
SEPQRRIGIIKLPGFYQDFEGRRRNAADYASATRDVAKLLAGFKTDKVDGVVLDLRNNGG
CCHHHCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
GSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLAVLINRGSASASEIF
CCHHHHHHHHHEEECCCCEEEEECCCCEEEECCCCCCCEEECCCEEEEEECCCCCHHHHH
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQH
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCCC
KGVVPDIAFPASVDATEFGESTYDNALPWTRIAAAPHTQYGNFAALLPKLQALHTARIAS
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHCC
DKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQRKDRQQIRKQLGLPLDPLAE
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCC
SPGRWAD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]