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The map label for this gene is mrdB [H]

Identifier: 21241431

GI number: 21241431

Start: 781974

End: 783092

Strand: Direct

Name: mrdB [H]

Synonym: XAC0660

Alternate gene names: 21241431

Gene position: 781974-783092 (Clockwise)

Preceding gene: 21241430

Following gene: 21241432

Centisome position: 15.11

GC content: 66.13

Gene sequence:

>1119_bases
TTGAGCGACATCCTGCGCTGGTTGGCGGACATGGCCGCGCGCTTTACGCGCAGCCTGGACTGGGTGCTGTGCCTGGCGCT
CGGCGGCCTGATGGCCATCGGCCTGTCGGTGCTCAAGAGCGCCGGCGGCACTGCCAATGGCGAGCACCTGATGCTGGCGC
AGGGCATCCGCTTCATCATCGGGTCGGCGGCGATGTGGGGCATCTCGCGCATGTCGGTACTGCGCCTGCGCGCCTGGACG
CCGTGGGTGTACGGCTTGTCGATGCTGCCGCTGCTGGCGGTCTTCGCCCTGGGCACCGGTAAATACGGCCGGCAGTGGCT
GGATCTGAAAGTGTTCTACCTGCAGCCGGCAGAGCTGCTCAAGATCAGCTTGCCGATGATGGCGGCCTGGTATCTGCACC
GCATGCCGCTGCCGCCGCGCATTTCCACCGTGCTGGTGACCGGCGTGATCATCGGCGTGCCCACCGCGCTGATCATGTTG
CAGCCGGACTTCGGCACCGGCGTGTTGATCGCTGCCAGCGGCGTGTTCGTGCTGCTGCTGGCCGGCCTGCCGTGGTGGTG
GGTGGCCGTCGGTGTGGGTGGGGTGTCTGCGGCTGCGCCGGTGGCATGGTTCTGGCTGCTGCGGCCGTACCAGAAGGACC
GCATCATGATGTTCCTCAACCCCGAGAACGATGCGCTTGGCGCGGGCTGGAACATCATCCAGTCCAAGATCGCGATTGGC
TCGGGCGGGTTGAACGGCAAGGGCTGGGGTCTGGGCTCGCAATCGCACCTGAACTTCATCCCCGAACAGACCACCGACTT
TGCGTTCTCCGTGCTCAGCGAAGAATTCGGCTGGATCGGCGTGGCCACCGTGCTGACCCTGTACCTGATCGTCATCGGCC
GCTGCCTGTGGATCGCCTCGCAGGCGCGCGACACTTATTCGCGCCTGGTTGCCGGCGCCACCGGCCTGGCGTTCTTCGTC
TACGTACTGGTCAACGGCGGCATGATCTCCGGCCTGCTGCCGGTGGTGGGCGTGCCGATGCCGCTGATGAGTTACGGCGG
TACCTCGGCGGTATCGCTGCTGGCCGGGCTGGGCTTGGTCATGGCAGTGAAGTCGCATCGCCCGGTGCATGGGTACTGA

Upstream 100 bases:

>100_bases
TGCCGGTGGTGATCGGCCAGAGCGCCGTTGCGCTGGACCCCAACATCCCCGCGCAACCGGTGGTGCCGGATGTGCCGGAC
GCGGTGCAGGAGACCGACCA

Downstream 100 bases:

>100_bases
GGCCGCGTCGCTGCACTGCATCGCGTACGTGCGCTTTGTGAGCGCCAGGCAGAGTGCCTGACGTGCGTCACACCAATCAC
TCCGCGCGCAGCAGGCCACA

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSDILRWLADMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGEHLMLAQGIRFIIGSAAMWGISRMSVLRLRAWT
PWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELLKISLPMMAAWYLHRMPLPPRISTVLVTGVIIGVPTALIML
QPDFGTGVLIAASGVFVLLLAGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIASQARDTYSRLVAGATGLAFFV
YVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLAGLGLVMAVKSHRPVHGY

Sequences:

>Translated_372_residues
MSDILRWLADMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGEHLMLAQGIRFIIGSAAMWGISRMSVLRLRAWT
PWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELLKISLPMMAAWYLHRMPLPPRISTVLVTGVIIGVPTALIML
QPDFGTGVLIAASGVFVLLLAGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIASQARDTYSRLVAGATGLAFFV
YVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLAGLGLVMAVKSHRPVHGY
>Mature_371_residues
SDILRWLADMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGEHLMLAQGIRFIIGSAAMWGISRMSVLRLRAWTP
WVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELLKISLPMMAAWYLHRMPLPPRISTVLVTGVIIGVPTALIMLQ
PDFGTGVLIAASGVFVLLLAGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIGS
GGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIASQARDTYSRLVAGATGLAFFVY
VLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLAGLGLVMAVKSHRPVHGY

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=292, Percent_Identity=50.3424657534247, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1786277, Length=270, Percent_Identity=35.5555555555556, Blast_Score=131, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40020; Mature: 39889

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDILRWLADMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGEHLMLAQGIRFII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
GSAAMWGISRMSVLRLRAWTPWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHH
KISLPMMAAWYLHRMPLPPRISTVLVTGVIIGVPTALIMLQPDFGTGVLIAASGVFVLLL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHHH
AGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
HCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHEEC
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIAS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QARDTYSRLVAGATGLAFFVYVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLAGLGLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHH
MAVKSHRPVHGY
HHHHCCCCCCCC
>Mature Secondary Structure 
SDILRWLADMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGEHLMLAQGIRFII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
GSAAMWGISRMSVLRLRAWTPWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHH
KISLPMMAAWYLHRMPLPPRISTVLVTGVIIGVPTALIMLQPDFGTGVLIAASGVFVLLL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHHH
AGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
HCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHEEC
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIAS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QARDTYSRLVAGATGLAFFVYVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLAGLGLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHH
MAVKSHRPVHGY
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]