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The map label for this gene is mdcB [H]

Identifier: 21241333

GI number: 21241333

Start: 663641

End: 664561

Strand: Direct

Name: mdcB [H]

Synonym: XAC0562

Alternate gene names: 21241333

Gene position: 663641-664561 (Clockwise)

Preceding gene: 21241332

Following gene: 21241334

Centisome position: 12.82

GC content: 66.99

Gene sequence:

>921_bases
ATGAGCACCACCGTTCCCATGGCCCAGCGCAGCTACTACGAAGCCGATGCCCGCGAACGTATCGATGGTCTGCTGGATGT
CGGCAGCCTTCGCGAATTCGTTGGCCCGCGGCGCCGCCTGATCAGCCCGCATCTGGCACAACTGGAGACACCCGGCGCCT
TCGATGACGGCATCGTGGTGGGCGAAGGCACCTTACGCGGCCGCAATGTCTTGATCGCTGCGCAGCAAGGCGCCTTCATG
GGCGGCGGCGTGGGCGAAGTGCATGGCGCCAAACTCACCGGCCTGCTGGAACGCGCCGCAACCACGCAGCCGGCAGCGGT
GCTATTGCTGCTGGACACCGGCGGCGTGCGTCTGCATGAGGCCAATGCCGGGCTCATCGCCATCTCCGAAATCATGCGAG
CCACCTTGAGCGCGCGTGCCGCCGGTGTGCCGGTGCTGGCCTTGATCGGCAGCGGCAACGGCGCGTTCGGCGGCATGGGC
ATCGTGGCGCGCTGCTGCAGCGCAGTGATCATGTCCGAAGAAGGCCGCTTGTCGTTGTCCGGCCCGGACGTGATCGAAAC
CGTGCGTGGGGTGGAAGAGTTCGACGCGCGCGACCGTGCCCTGGTGTGGCGCGTGACCGGCGGCAAACACCGCTACCTGC
TGGGCGAGGCGCAAACGCTGGTGGCCGATCGCATCGATGCCTTCGCCGATGCAGCGCTGGCCACCCTCGATGCTCTCACC
GAAGCGACGGGTGAGGCCGCATTGCAGGCGCTGGAGCGTGCGCAGCAGCAATTGGCAGCGCGCATCGATGCGTACGGCGA
TTGCCGCGACGGACTGGAGATCTGGACGCGCCAGGGCATTGTCGATGCGCAGCGCCTGCCGCTGCTCGATACCGAGGCCT
TTCTTGCCGCAACCGCAGACCGGAGCCTTCCATGGACCTGA

Upstream 100 bases:

>100_bases
ACTGTCACCCCGTAGGAGCGCACCAGGGCGCGACGGGCATTCCCGGTAAGGCTTCAGTCGCGCCCCGGTGCGCTCCTACG
CAAGCGATCGGGAGATACGC

Downstream 100 bases:

>100_bases
GCCGCTTGCTCGATCAGCTGTTTCCGCTCGGTCACGCCATCGCGCGCAACGACGATGTGCTCACCGGCAGTGCAACCACC
GCCGCCGGCGACGTCACCGT

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSTTVPMAQRSYYEADARERIDGLLDVGSLREFVGPRRRLISPHLAQLETPGAFDDGIVVGEGTLRGRNVLIAAQQGAFM
GGGVGEVHGAKLTGLLERAATTQPAAVLLLLDTGGVRLHEANAGLIAISEIMRATLSARAAGVPVLALIGSGNGAFGGMG
IVARCCSAVIMSEEGRLSLSGPDVIETVRGVEEFDARDRALVWRVTGGKHRYLLGEAQTLVADRIDAFADAALATLDALT
EATGEAALQALERAQQQLAARIDAYGDCRDGLEIWTRQGIVDAQRLPLLDTEAFLAATADRSLPWT

Sequences:

>Translated_306_residues
MSTTVPMAQRSYYEADARERIDGLLDVGSLREFVGPRRRLISPHLAQLETPGAFDDGIVVGEGTLRGRNVLIAAQQGAFM
GGGVGEVHGAKLTGLLERAATTQPAAVLLLLDTGGVRLHEANAGLIAISEIMRATLSARAAGVPVLALIGSGNGAFGGMG
IVARCCSAVIMSEEGRLSLSGPDVIETVRGVEEFDARDRALVWRVTGGKHRYLLGEAQTLVADRIDAFADAALATLDALT
EATGEAALQALERAQQQLAARIDAYGDCRDGLEIWTRQGIVDAQRLPLLDTEAFLAATADRSLPWT
>Mature_305_residues
STTVPMAQRSYYEADARERIDGLLDVGSLREFVGPRRRLISPHLAQLETPGAFDDGIVVGEGTLRGRNVLIAAQQGAFMG
GGVGEVHGAKLTGLLERAATTQPAAVLLLLDTGGVRLHEANAGLIAISEIMRATLSARAAGVPVLALIGSGNGAFGGMGI
VARCCSAVIMSEEGRLSLSGPDVIETVRGVEEFDARDRALVWRVTGGKHRYLLGEAQTLVADRIDAFADAALATLDALTE
ATGEAALQALERAQQQLAARIDAYGDCRDGLEIWTRQGIVDAQRLPLLDTEAFLAATADRSLPWT

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI25147362, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147359, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 32284; Mature: 32153

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTVPMAQRSYYEADARERIDGLLDVGSLREFVGPRRRLISPHLAQLETPGAFDDGIVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHCCCCCCCCCCEEE
GEGTLRGRNVLIAAQQGAFMGGGVGEVHGAKLTGLLERAATTQPAAVLLLLDTGGVRLHE
ECCCCCCCEEEEEECCCCEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEEEE
ANAGLIAISEIMRATLSARAAGVPVLALIGSGNGAFGGMGIVARCCSAVIMSEEGRLSLS
CCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEC
GPDVIETVRGVEEFDARDRALVWRVTGGKHRYLLGEAQTLVADRIDAFADAALATLDALT
CCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
EATGEAALQALERAQQQLAARIDAYGDCRDGLEIWTRQGIVDAQRLPLLDTEAFLAATAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHCC
RSLPWT
CCCCCC
>Mature Secondary Structure 
STTVPMAQRSYYEADARERIDGLLDVGSLREFVGPRRRLISPHLAQLETPGAFDDGIVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHCCCCCCCCCCEEE
GEGTLRGRNVLIAAQQGAFMGGGVGEVHGAKLTGLLERAATTQPAAVLLLLDTGGVRLHE
ECCCCCCCEEEEEECCCCEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEEEE
ANAGLIAISEIMRATLSARAAGVPVLALIGSGNGAFGGMGIVARCCSAVIMSEEGRLSLS
CCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEC
GPDVIETVRGVEEFDARDRALVWRVTGGKHRYLLGEAQTLVADRIDAFADAALATLDALT
CCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
EATGEAALQALERAQQQLAARIDAYGDCRDGLEIWTRQGIVDAQRLPLLDTEAFLAATAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHCC
RSLPWT
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]