Click here to switch to the map view.

The map label for this gene is ycbU [H]

Identifier: 21240958

GI number: 21240958

Start: 226327

End: 227508

Strand: Reverse

Name: ycbU [H]

Synonym: XAC0184

Alternate gene names: 21240958

Gene position: 227508-226327 (Counterclockwise)

Preceding gene: 21240961

Following gene: 21240953

Centisome position: 4.4

GC content: 67.26

Gene sequence:

>1182_bases
ATGTCATCGCCATCTCTGTCCAGTACGCTTGCTGCACCCCTCGACTGGGCCCAGCGTCAGCAGGCATTTGCGCTGCCTTC
CGGGGTCATCTATCTGGATGCGGCGTCGCGCGGGCCGTTGTTGCGCGCCATGCAGACGGTGGCGCACCAGGCGGTTGACG
CAATGGCCGCACCATGGCGGTTGCCGTTCGATGCGTGGTTGCAGCAGATCGAAGTATTGCGCGGGCTTGCGGCCGCGCTA
TTGGATGGCGATGCCGATGCGGTGGCCATGGTGCCGTCGGCCGCGCACGGCTTGGCCACGGCCGCACGCAATCTGCCCGT
GCAACCCGGCCACGCAGTGCTGGTGCTGGAAGGGCAATTCCCTTCCAATCTGTTGATCTGGCAGCGCCGCTGCGCAGAGG
CCGGCGCGCGTCTTGTGCCGGTGCCCACGGCCGCTGGCGGCAACTTGACCGATGCGGTGCTGCAGGTCATTGCCGAGACG
CCTGCGCTGCGGATTGCGAGCTTGCCGCATGCATACTGGCTGGACGGGCGAATGCTGGATCTGGACCGCATCAGTGCCGC
CGTGCATGCACGCGGGGCTGCCCTGGTGCTGGACCTAAGCCAGAGCCTGGGGGTGTTGCCACCCGATCTGCTCCGCTGGC
AACCGGATTTCGTGGTCAGCGTCGGGCACAAATGGTTGCTCGGGCCGATGGGATTGGCGTGGCTGTGGGTGGCACCGCAG
TGGCGTACAGACGGGCTGCCGATCGAAGAACACTGGATCGGCCGCGATGCGGGCAGCAGTTGGGAATTTCCGGCGGCCAA
CGCGCCGGGATATCGCGGCGGTGCACGGCGATTCGATGCGGGCGGAGTGGCCGACCCGTTGCGGATCGCAATGGCTACGG
TGGCCTTGCAACAACTCAACGCGTGGCAGCCGGCGCGTATCGCAGCCGCGTTGGGCGAGTTGACCGCGCATTGGGACGCC
GCCCTGCAGGCGCGCGGCTTGGGCAGCTGGTGCACGCCTGGACATGCGCCGCATCTCACCGCACTGCAGCCGCCGGCAGC
AGCGTTGGATGCGGTGGCAACGGCGCTCGGCGCCGGTGGTGTGGTCTGCACGCGTCGGCATGGACGTCTGCGCATCGCAC
CGCATTTGAGCGTCACCGACCACGCGTTGTCACAGGTCGTTGCAGCGCTACCCGATAGGTGA

Upstream 100 bases:

>100_bases
TGGCCCAGCAGAGGAGAGAGTGCAGACATCGCCATATGCTTGGGTAGCGCCCGTGAACGTGCTGTGTCGGCAACGTGGCA
GCCAGCGGTAAGCTGTAGAC

Downstream 100 bases:

>100_bases
GGCGCGGCGCACGCCGACATCGAAGGCCCGGCATCTGCAGCGATGCAGGCCTGCGCGCGGTCAGTAGCACCGGAAGGTTT
CATCGAAGGCCAGTGAGCCC

Product: hypothetical protein

Products: hydrogen selenide; @ALAN01.txt*l-alanine!; acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSSPSLSSTLAAPLDWAQRQQAFALPSGVIYLDAASRGPLLRAMQTVAHQAVDAMAAPWRLPFDAWLQQIEVLRGLAAAL
LDGDADAVAMVPSAAHGLATAARNLPVQPGHAVLVLEGQFPSNLLIWQRRCAEAGARLVPVPTAAGGNLTDAVLQVIAET
PALRIASLPHAYWLDGRMLDLDRISAAVHARGAALVLDLSQSLGVLPPDLLRWQPDFVVSVGHKWLLGPMGLAWLWVAPQ
WRTDGLPIEEHWIGRDAGSSWEFPAANAPGYRGGARRFDAGGVADPLRIAMATVALQQLNAWQPARIAAALGELTAHWDA
ALQARGLGSWCTPGHAPHLTALQPPAAALDAVATALGAGGVVCTRRHGRLRIAPHLSVTDHALSQVVAALPDR

Sequences:

>Translated_393_residues
MSSPSLSSTLAAPLDWAQRQQAFALPSGVIYLDAASRGPLLRAMQTVAHQAVDAMAAPWRLPFDAWLQQIEVLRGLAAAL
LDGDADAVAMVPSAAHGLATAARNLPVQPGHAVLVLEGQFPSNLLIWQRRCAEAGARLVPVPTAAGGNLTDAVLQVIAET
PALRIASLPHAYWLDGRMLDLDRISAAVHARGAALVLDLSQSLGVLPPDLLRWQPDFVVSVGHKWLLGPMGLAWLWVAPQ
WRTDGLPIEEHWIGRDAGSSWEFPAANAPGYRGGARRFDAGGVADPLRIAMATVALQQLNAWQPARIAAALGELTAHWDA
ALQARGLGSWCTPGHAPHLTALQPPAAALDAVATALGAGGVVCTRRHGRLRIAPHLSVTDHALSQVVAALPDR
>Mature_392_residues
SSPSLSSTLAAPLDWAQRQQAFALPSGVIYLDAASRGPLLRAMQTVAHQAVDAMAAPWRLPFDAWLQQIEVLRGLAAALL
DGDADAVAMVPSAAHGLATAARNLPVQPGHAVLVLEGQFPSNLLIWQRRCAEAGARLVPVPTAAGGNLTDAVLQVIAETP
ALRIASLPHAYWLDGRMLDLDRISAAVHARGAALVLDLSQSLGVLPPDLLRWQPDFVVSVGHKWLLGPMGLAWLWVAPQW
RTDGLPIEEHWIGRDAGSSWEFPAANAPGYRGGARRFDAGGVADPLRIAMATVALQQLNAWQPARIAAALGELTAHWDAA
LQARGLGSWCTPGHAPHLTALQPPAAALDAVATALGAGGVVCTRRHGRLRIAPHLSVTDHALSQVVAALPDR

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.8.1.7 [C]

Molecular weight: Translated: 41509; Mature: 41378

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPSLSSTLAAPLDWAQRQQAFALPSGVIYLDAASRGPLLRAMQTVAHQAVDAMAAPWR
CCCCCCCHHHHCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
LPFDAWLQQIEVLRGLAAALLDGDADAVAMVPSAAHGLATAARNLPVQPGHAVLVLEGQF
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCC
PSNLLIWQRRCAEAGARLVPVPTAAGGNLTDAVLQVIAETPALRIASLPHAYWLDGRMLD
CCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEECCCEEEC
LDRISAAVHARGAALVLDLSQSLGVLPPDLLRWQPDFVVSVGHKWLLGPMGLAWLWVAPQ
HHHHHHHHHCCCCEEEEECHHHCCCCCHHHHCCCCCEEEECCCCEEECCCCEEEEEECCC
WRTDGLPIEEHWIGRDAGSSWEFPAANAPGYRGGARRFDAGGVADPLRIAMATVALQQLN
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
AWQPARIAAALGELTAHWDAALQARGLGSWCTPGHAPHLTALQPPAAALDAVATALGAGG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
VVCTRRHGRLRIAPHLSVTDHALSQVVAALPDR
EEEEECCCEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSPSLSSTLAAPLDWAQRQQAFALPSGVIYLDAASRGPLLRAMQTVAHQAVDAMAAPWR
CCCCCCHHHHCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
LPFDAWLQQIEVLRGLAAALLDGDADAVAMVPSAAHGLATAARNLPVQPGHAVLVLEGQF
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCC
PSNLLIWQRRCAEAGARLVPVPTAAGGNLTDAVLQVIAETPALRIASLPHAYWLDGRMLD
CCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEECCCEEEC
LDRISAAVHARGAALVLDLSQSLGVLPPDLLRWQPDFVVSVGHKWLLGPMGLAWLWVAPQ
HHHHHHHHHCCCCEEEEECHHHCCCCCHHHHCCCCCEEEECCCCEEECCCCEEEEEECCC
WRTDGLPIEEHWIGRDAGSSWEFPAANAPGYRGGARRFDAGGVADPLRIAMATVALQQLN
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
AWQPARIAAALGELTAHWDAALQARGLGSWCTPGHAPHLTALQPPAAALDAVATALGAGG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
VVCTRRHGRLRIAPHLSVTDHALSQVVAALPDR
EEEEECCCEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal phosphate [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-selenocysteine; reduced acceptor [C]

Specific reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + @ALAN01.txt*l-alanine! + acceptor [C]

General reaction: Elimination of H2S or RSH [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 7704254; 1353026 [H]