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The map label for this gene is hipA [H]

Identifier: 21240961

GI number: 21240961

Start: 230156

End: 230734

Strand: Reverse

Name: hipA [H]

Synonym: XAC0187

Alternate gene names: 21240961

Gene position: 230734-230156 (Counterclockwise)

Preceding gene: 21240962

Following gene: 21240958

Centisome position: 4.46

GC content: 64.25

Gene sequence:

>579_bases
GTGAGACTGGTCGCGCTGATCGAAAACCAAACGATCGGGCACCTCGCGTCCGACCCGCACGGGCATCCACGATTCACCTA
CGCGCCGGACTGGCAGCATTCAAAGAGTGCGATACCGCTGTCTTTGAACCTTCCCCTCAGCAGGGAACATCACCCGACCG
AGGCGGTCAGTGCAGTGCTGTGGGGCCTGCTGCCAGACAACGAAGCCACCTTGCAACGCTGGGCCTCCAGGTTCCAGGTC
TCGCCGCGCAATCCGCTCGCCCTGTTGTCGCATGTGGGCGAGGATTGCGCTGGTGCGGTGCAGTTCGTCACCGAAGCGAG
GCTCGAAGATGTGCTGTCCGGCGCCAGCGATGGCATCGAACCGCTCACCGATGGCGAACTGGAAGCACGCTTGCGCAGGC
TGCGTCAGGACATCGGTGCGGCGCGCCAAGTCGAAGACGTGGGGCAGTTCAGCCTGGCCGGCGCGCAGGCCAAGATCGCA
TTGCTGCACGACGGCCTGCAGTGGGCCATCCCGGCCGGACGCATCCCGACCACGCATATCCTCAAACCACCGAGCGGCGA
ATCCCGTTACACATGGTAG

Upstream 100 bases:

>100_bases
GCTTGAAGATTGGCGAGACAGTAGCTGATAGTTTGAAGATCGGCGAGGCAGAGAAAATATCCAAGGTCATCTCGCCATCT
TCCAAAAAGAAGGGCGTTCC

Downstream 100 bases:

>100_bases
CTGGCGCATCCAATCGATGGGGCGTCAGTCGAAATGCGGCCCGCGCATCAGGCGAATCGGTCCGCGAACATCGGGCAGTT
GCACCGTTCTGCCTTGCTGG

Product: HipA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRLVALIENQTIGHLASDPHGHPRFTYAPDWQHSKSAIPLSLNLPLSREHHPTEAVSAVLWGLLPDNEATLQRWASRFQV
SPRNPLALLSHVGEDCAGAVQFVTEARLEDVLSGASDGIEPLTDGELEARLRRLRQDIGAARQVEDVGQFSLAGAQAKIA
LLHDGLQWAIPAGRIPTTHILKPPSGESRYTW

Sequences:

>Translated_192_residues
MRLVALIENQTIGHLASDPHGHPRFTYAPDWQHSKSAIPLSLNLPLSREHHPTEAVSAVLWGLLPDNEATLQRWASRFQV
SPRNPLALLSHVGEDCAGAVQFVTEARLEDVLSGASDGIEPLTDGELEARLRRLRQDIGAARQVEDVGQFSLAGAQAKIA
LLHDGLQWAIPAGRIPTTHILKPPSGESRYTW
>Mature_192_residues
MRLVALIENQTIGHLASDPHGHPRFTYAPDWQHSKSAIPLSLNLPLSREHHPTEAVSAVLWGLLPDNEATLQRWASRFQV
SPRNPLALLSHVGEDCAGAVQFVTEARLEDVLSGASDGIEPLTDGELEARLRRLRQDIGAARQVEDVGQFSLAGAQAKIA
LLHDGLQWAIPAGRIPTTHILKPPSGESRYTW

Specific function: Unbalanced or excessive expression of hipA is toxic to the cell [H]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0665 [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=190, Percent_Identity=40, Blast_Score=123, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 21032; Mature: 21032

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVALIENQTIGHLASDPHGHPRFTYAPDWQHSKSAIPLSLNLPLSREHHPTEAVSAVL
CEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
WGLLPDNEATLQRWASRFQVSPRNPLALLSHVGEDCAGAVQFVTEARLEDVLSGASDGIE
HHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLTDGELEARLRRLRQDIGAARQVEDVGQFSLAGAQAKIALLHDGLQWAIPAGRIPTTHI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCCCCEE
LKPPSGESRYTW
ECCCCCCCCCCC
>Mature Secondary Structure
MRLVALIENQTIGHLASDPHGHPRFTYAPDWQHSKSAIPLSLNLPLSREHHPTEAVSAVL
CEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
WGLLPDNEATLQRWASRFQVSPRNPLALLSHVGEDCAGAVQFVTEARLEDVLSGASDGIE
HHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLTDGELEARLRRLRQDIGAARQVEDVGQFSLAGAQAKIALLHDGLQWAIPAGRIPTTHI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCCCCEE
LKPPSGESRYTW
ECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1715862; 9278503; 8021189 [H]