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The map label for this gene is atpD [H]

Identifier: 21226880

GI number: 21226880

Start: 930996

End: 931634

Strand: Reverse

Name: atpD [H]

Synonym: MM_0778

Alternate gene names: 21226880

Gene position: 931634-930996 (Counterclockwise)

Preceding gene: 21226881

Following gene: 21226879

Centisome position: 22.74

GC content: 44.44

Gene sequence:

>639_bases
GTGATTGCCATGGCTCAGCAGGACGTAAAACCAACTCGTTCGGAGTTAATTAATCTCAAGAAAAAGATCAAGCTCTCTGA
AAGTGGGCACAAGCTCCTGAAGATGAAAAGAGACGGTCTGATCCTTGAGTTCTTCAAGATCCTTAACGAAGCAAGGAATG
TCAGAACCGAGCTGGATGCTGCCTTTGCAAAGAGTACTGAAAAAATCAATCTTGCCTCTGCTGTAAATGGAATGGTTGCA
GTAAGGTCAACCGCCTTTACAGCAAAAGAATCCCCTGAAATCCAGCTTTCAGGGCACAACATCATGGGTGTTGTGGTGCC
AAAGATCAGCTCTACAGGTGTCCGCAAGTCCCTCTATGAGAGGGGATATGGTATTATCGGAACAAATTCATATATTGATG
AAACTGCTGATGCCTACGAGGACCTTGTAGAAAAGATCATCACTGCAGCAGAGCTTGAGACTACAATGAAAAGGCTCCTT
GATGAGATCGAGAAGACCAAGAGGCGTGTTAACGCTCTGGAATTCAAGGTGATTCCCGAACTCATTGATACCATGAAGTA
CATCCGCTTCATGCTTGAAGAGATGGAAAGAGAAAACACCTTCAGGCTGAAGAGAGTCAAGGCAAGAATGAGAGATTAA

Upstream 100 bases:

>100_bases
AGATCGGATGGCAGATTCTCACTCACCTTCCTGAAAACCAGTTGGGTAGGATTGACAACAAATATATCCAGAAATATCAC
CCGGCACACAGAAAGGCTAA

Downstream 100 bases:

>100_bases
GTTTGATTTGAACATGGCAGAATGCGACGATCGACCTAATCTGGTTGAAAGAGCAGTAATGAAGTTAGGTGAACCCAAAA
ACCAGGCCCGCCTGTTGCAG

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MIAMAQQDVKPTRSELINLKKKIKLSESGHKLLKMKRDGLILEFFKILNEARNVRTELDAAFAKSTEKINLASAVNGMVA
VRSTAFTAKESPEIQLSGHNIMGVVVPKISSTGVRKSLYERGYGIIGTNSYIDETADAYEDLVEKIITAAELETTMKRLL
DEIEKTKRRVNALEFKVIPELIDTMKYIRFMLEEMERENTFRLKRVKARMRD

Sequences:

>Translated_212_residues
MIAMAQQDVKPTRSELINLKKKIKLSESGHKLLKMKRDGLILEFFKILNEARNVRTELDAAFAKSTEKINLASAVNGMVA
VRSTAFTAKESPEIQLSGHNIMGVVVPKISSTGVRKSLYERGYGIIGTNSYIDETADAYEDLVEKIITAAELETTMKRLL
DEIEKTKRRVNALEFKVIPELIDTMKYIRFMLEEMERENTFRLKRVKARMRD
>Mature_212_residues
MIAMAQQDVKPTRSELINLKKKIKLSESGHKLLKMKRDGLILEFFKILNEARNVRTELDAAFAKSTEKINLASAVNGMVA
VRSTAFTAKESPEIQLSGHNIMGVVVPKISSTGVRKSLYERGYGIIGTNSYIDETADAYEDLVEKIITAAELETTMKRLL
DEIEKTKRRVNALEFKVIPELIDTMKYIRFMLEEMERENTFRLKRVKARMRD

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family [H]

Homologues:

Organism=Homo sapiens, GI7706757, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17553636, Length=206, Percent_Identity=31.0679611650485, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320784, Length=212, Percent_Identity=28.7735849056604, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355551, Length=207, Percent_Identity=28.9855072463768, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20128937, Length=217, Percent_Identity=29.0322580645161, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002699 [H]

Pfam domain/function: PF01813 ATP-synt_D [H]

EC number: 3.6.3.14

Molecular weight: Translated: 24217; Mature: 24217

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAMAQQDVKPTRSELINLKKKIKLSESGHKLLKMKRDGLILEFFKILNEARNVRTELDA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFAKSTEKINLASAVNGMVAVRSTAFTAKESPEIQLSGHNIMGVVVPKISSTGVRKSLYE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHH
RGYGIIGTNSYIDETADAYEDLVEKIITAAELETTMKRLLDEIEKTKRRVNALEFKVIPE
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDTMKYIRFMLEEMERENTFRLKRVKARMRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAMAQQDVKPTRSELINLKKKIKLSESGHKLLKMKRDGLILEFFKILNEARNVRTELDA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFAKSTEKINLASAVNGMVAVRSTAFTAKESPEIQLSGHNIMGVVVPKISSTGVRKSLYE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHH
RGYGIIGTNSYIDETADAYEDLVEKIITAAELETTMKRLLDEIEKTKRRVNALEFKVIPE
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDTMKYIRFMLEEMERENTFRLKRVKARMRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]