| Definition | Methanosarcina mazei Go1 chromosome, complete genome. |
|---|---|
| Accession | NC_003901 |
| Length | 4,096,345 |
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The map label for this gene is hypF [H]
Identifier: 21226879
GI number: 21226879
Start: 927999
End: 930317
Strand: Reverse
Name: hypF [H]
Synonym: MM_0777
Alternate gene names: 21226879
Gene position: 930317-927999 (Counterclockwise)
Preceding gene: 21226880
Following gene: 21226878
Centisome position: 22.71
GC content: 48.08
Gene sequence:
>2319_bases ATGCAAAACGAGTCAAGGCTTCTCCATATTACCGGTATTGTACAGGGTGTAGGTTTTCGCCCTTTTATATATCAGCTTGC AAAAGCCAATGGGCTTTCCGGATACGTGAAAAATCTGGGAAACTACGTGGAAATCCTTATAGAAGGAGATCGGGAATGCC TTGATAATTTTCTTAAAGAACTTCCTGAAAAAAAACCTCCTCTTGCTAAAATTACTGAACTCAGAACAAAGAACGTGCCT TTTTCAGGATATTCCGGATTTATTATCGTTCCCAGTGAATCCGGAGTATTTGAAAATTCCATAATTCCTCCAGATACGGC TATTTGTGAACAGTGCAGGTCTGAGATTTTCGATCCTTCTTCCAGGTATTACCATTATCCTTTTACCGTATGCACAAATT GCGGGCCCAGGTATACAACAGTAAGAACCCTACCTTACGACCGGGAAAATACCACTATGGCAGATTTTCCCCTCTGTCCG GAGTGCGAAAAAGAGTATACTGACCCTCTTAATCGAAGGTATCACGCGCAGCCTGTTTGCTGCCCGAAGTGCGGGCCTGA GATCTGGCTTTCCGATCGTGAAGGAAATGTACTGTCAAGAGGTTATGAAGCAATTGCCAGTGCCTCAGACCTCCTTCAGG AAGGCTCGATTCTTGCTGTAAAAGGCTTCGGAGGTTTCCATATTGCCTGCAACGCACGACAGGAAGAACCCGTAAATGAG CTCAGGAGACGGTTAAAGCGTCCGGAGCAACCTTTTGCGGTCATGGCAAAAAATGCAGGTGTTGCGGAATCTTTTGCAGA TCTTGAAGGCGCAGGCAGGGAATATCTCACCTCTCACCGCCGGCCTATCACAGTGCTTCCCAGGTCAGAAGAATTCAATC TGGCAGATTCGGTTTCTCCCGGACTGCACAATATAGGGGTCATGCTCCCCTACACAGGCACACAGAATCTGCTTTTTGAC CGTGTGCCTGATGCTGTATATGTTATGACCTCGGCGAATCTCCCGGGAAGGCCAATGGTCGTTGATAACAGGGAGGCTCT CGAAAAACTGAAAGGAATCGTCGACTTTTACCTTCTGCACAACAGGGTCATTGCAAACAGGAACGATGATACGGTTATCC GTATTGTAAATGGGCAGGCTGCCTTTATCCGGCGTTCCCGCGGATATGTGCCTGAACCCGTGGAACTGCCTTTTGAAATA GAAGCTTCTATAGGGGTTGGCGCTGAGATGAATTCTACCGTTACCGTGGCAAAGGGAAAACTTGCCTATATATCCCAGTA TATAGGAAATACCAGCCATGTGGAAACCTACAGGTATCACTCCGAGGTTGTCAGGCACCTTATCCGGCTTACCGGAATTG AACCTCTCCACTGGAGCTGTGACCTTCACCCTTCATTCAACACAACCCGTTTTGCGCTGAAAATGGGAGGGGAGAATACA CTCAAGATCCAGCATCATTACGCCCATATGCTGGCACTCATGGCTGACAACTCCCTGCCTCTGGGTTCCAGAATTCTCGG AATCGCTCTTGATGGGGTAGGATATGGAGGTGACGGGACAATCTGGGGCGGAGAACTCTTTGAATCATCTTACTTCGGAT ACGAACGTATAGGGCATTTACTCCCTCAACCAATGCCGGGCGGAGACCTTGCTTCCAGGGTACCTTCAAGGATGGTCCTT GGTATCCTTTTCGAGAAGCTTGGGAGACCAGAACTGGAAAAACTCCCCCTTGTTTTTCCTCAGGGGGACAGGGAGCTTTC AACTGTGTTGAAACAGCTTGAAACCGGGATAAATGTTGTCCAGAGCAGCAGTACCGGGAGAGTACTTGATGCCGCCTCTG CACTTCTTGAAATCTGCAAAATAAGGACCTATGATGGAGAGCCTGCAATGAAGCTCGAATCTGCCGCAAAGAAAAGCACG CATGTTGTCGATCTTCCCATAGTATTCAAAAAATACGGGGGCTCAGGAGTTCCTGTGCTTGATACTACCGAGCTTCTTCT TGGGGCATATGAGCTTTCCGGTAAGTATTCTCCTGAAAATCTTGCTTTTGCGGTTGAGGAAAGCCTTGCAAAGGGAATTT CAGAACTTTCCTTATCTCTTGCCGCAAAAAGAGGGCTTGAGAAGATAGGTCTGAGCGGAGGAGTTGCCTATAATGATCAC ATCACCTCGTGCATTGCAGGAACTGTTGCAGAAGCAGGTTTTGAGTTCCTCGCCCACCGCCAGGCGCCGTGCGGAGACGG ATGTATTTCATTCGGGCAGGCAATAGCAGGCGGGCTCAGAACAGATCCAGAAAGTAATCAGGTTCCGGAGAGAGTTTAA
Upstream 100 bases:
>100_bases CATATTTTAATCTATTAATGATATATTACTAATGATGTATTGCTGGATGTTTTTATTATTTAGAAAGCTATTTTAATGAC AAACGGTAATCTTTGCATAT
Downstream 100 bases:
>100_bases TAGAGGAAATAACCAACTTTCACAGCTTCTGATGTTTCCCGTCAGGGGCTTACTCATCCAACATACTGAAATTTGATCCT GAAAACTGGAATACAAAATT
Product: hydrogenase maturation protein
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF; [NiFe]-hydrogenase maturation factor hypF; Hydrogenase maturation protein hypF [H]
Number of amino acids: Translated: 772; Mature: 772
Protein sequence:
>772_residues MQNESRLLHITGIVQGVGFRPFIYQLAKANGLSGYVKNLGNYVEILIEGDRECLDNFLKELPEKKPPLAKITELRTKNVP FSGYSGFIIVPSESGVFENSIIPPDTAICEQCRSEIFDPSSRYYHYPFTVCTNCGPRYTTVRTLPYDRENTTMADFPLCP ECEKEYTDPLNRRYHAQPVCCPKCGPEIWLSDREGNVLSRGYEAIASASDLLQEGSILAVKGFGGFHIACNARQEEPVNE LRRRLKRPEQPFAVMAKNAGVAESFADLEGAGREYLTSHRRPITVLPRSEEFNLADSVSPGLHNIGVMLPYTGTQNLLFD RVPDAVYVMTSANLPGRPMVVDNREALEKLKGIVDFYLLHNRVIANRNDDTVIRIVNGQAAFIRRSRGYVPEPVELPFEI EASIGVGAEMNSTVTVAKGKLAYISQYIGNTSHVETYRYHSEVVRHLIRLTGIEPLHWSCDLHPSFNTTRFALKMGGENT LKIQHHYAHMLALMADNSLPLGSRILGIALDGVGYGGDGTIWGGELFESSYFGYERIGHLLPQPMPGGDLASRVPSRMVL GILFEKLGRPELEKLPLVFPQGDRELSTVLKQLETGINVVQSSSTGRVLDAASALLEICKIRTYDGEPAMKLESAAKKST HVVDLPIVFKKYGGSGVPVLDTTELLLGAYELSGKYSPENLAFAVEESLAKGISELSLSLAAKRGLEKIGLSGGVAYNDH ITSCIAGTVAEAGFEFLAHRQAPCGDGCISFGQAIAGGLRTDPESNQVPERV
Sequences:
>Translated_772_residues MQNESRLLHITGIVQGVGFRPFIYQLAKANGLSGYVKNLGNYVEILIEGDRECLDNFLKELPEKKPPLAKITELRTKNVP FSGYSGFIIVPSESGVFENSIIPPDTAICEQCRSEIFDPSSRYYHYPFTVCTNCGPRYTTVRTLPYDRENTTMADFPLCP ECEKEYTDPLNRRYHAQPVCCPKCGPEIWLSDREGNVLSRGYEAIASASDLLQEGSILAVKGFGGFHIACNARQEEPVNE LRRRLKRPEQPFAVMAKNAGVAESFADLEGAGREYLTSHRRPITVLPRSEEFNLADSVSPGLHNIGVMLPYTGTQNLLFD RVPDAVYVMTSANLPGRPMVVDNREALEKLKGIVDFYLLHNRVIANRNDDTVIRIVNGQAAFIRRSRGYVPEPVELPFEI EASIGVGAEMNSTVTVAKGKLAYISQYIGNTSHVETYRYHSEVVRHLIRLTGIEPLHWSCDLHPSFNTTRFALKMGGENT LKIQHHYAHMLALMADNSLPLGSRILGIALDGVGYGGDGTIWGGELFESSYFGYERIGHLLPQPMPGGDLASRVPSRMVL GILFEKLGRPELEKLPLVFPQGDRELSTVLKQLETGINVVQSSSTGRVLDAASALLEICKIRTYDGEPAMKLESAAKKST HVVDLPIVFKKYGGSGVPVLDTTELLLGAYELSGKYSPENLAFAVEESLAKGISELSLSLAAKRGLEKIGLSGGVAYNDH ITSCIAGTVAEAGFEFLAHRQAPCGDGCISFGQAIAGGLRTDPESNQVPERV >Mature_772_residues MQNESRLLHITGIVQGVGFRPFIYQLAKANGLSGYVKNLGNYVEILIEGDRECLDNFLKELPEKKPPLAKITELRTKNVP FSGYSGFIIVPSESGVFENSIIPPDTAICEQCRSEIFDPSSRYYHYPFTVCTNCGPRYTTVRTLPYDRENTTMADFPLCP ECEKEYTDPLNRRYHAQPVCCPKCGPEIWLSDREGNVLSRGYEAIASASDLLQEGSILAVKGFGGFHIACNARQEEPVNE LRRRLKRPEQPFAVMAKNAGVAESFADLEGAGREYLTSHRRPITVLPRSEEFNLADSVSPGLHNIGVMLPYTGTQNLLFD RVPDAVYVMTSANLPGRPMVVDNREALEKLKGIVDFYLLHNRVIANRNDDTVIRIVNGQAAFIRRSRGYVPEPVELPFEI EASIGVGAEMNSTVTVAKGKLAYISQYIGNTSHVETYRYHSEVVRHLIRLTGIEPLHWSCDLHPSFNTTRFALKMGGENT LKIQHHYAHMLALMADNSLPLGSRILGIALDGVGYGGDGTIWGGELFESSYFGYERIGHLLPQPMPGGDLASRVPSRMVL GILFEKLGRPELEKLPLVFPQGDRELSTVLKQLETGINVVQSSSTGRVLDAASALLEICKIRTYDGEPAMKLESAAKKST HVVDLPIVFKKYGGSGVPVLDTTELLLGAYELSGKYSPENLAFAVEESLAKGISELSLSLAAKRGLEKIGLSGGVAYNDH ITSCIAGTVAEAGFEFLAHRQAPCGDGCISFGQAIAGGLRTDPESNQVPERV
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=760, Percent_Identity=35.7894736842105, Blast_Score=418, Evalue=1e-118,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 84808; Mature: 84808
Theoretical pI: Translated: 6.22; Mature: 6.22
Prosite motif: PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQNESRLLHITGIVQGVGFRPFIYQLAKANGLSGYVKNLGNYVEILIEGDRECLDNFLKE CCCCCCEEEEEEEHHCCCCHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHH LPEKKPPLAKITELRTKNVPFSGYSGFIIVPSESGVFENSIIPPDTAICEQCRSEIFDPS CCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCC SRYYHYPFTVCTNCGPRYTTVRTLPYDRENTTMADFPLCPECEKEYTDPLNRRYHAQPVC CCEEECCEEEECCCCCCEEEEEECCCCCCCCEEECCCCCCCHHHHHCCHHHCCCCCCCCC CPKCGPEIWLSDREGNVLSRGYEAIASASDLLQEGSILAVKGFGGFHIACNARQEEPVNE CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHH LRRRLKRPEQPFAVMAKNAGVAESFADLEGAGREYLTSHRRPITVLPRSEEFNLADSVSP HHHHHCCCCCCCEEEECCCCCHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCCHHCCCC GLHNIGVMLPYTGTQNLLFDRVPDAVYVMTSANLPGRPMVVDNREALEKLKGIVDFYLLH CHHHCCEEEECCCCCHHHHHCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHH NRVIANRNDDTVIRIVNGQAAFIRRSRGYVPEPVELPFEIEASIGVGAEMNSTVTVAKGK HHHEECCCCCCEEEEECCCEEEHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCH LAYISQYIGNTSHVETYRYHSEVVRHLIRLTGIEPLHWSCDLHPSFNTTRFALKMGGENT HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCE LKIQHHYAHMLALMADNSLPLGSRILGIALDGVGYGGDGTIWGGELFESSYFGYERIGHL EEEHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCEECHHHHHHCCCCHHHHHHH LPQPMPGGDLASRVPSRMVLGILFEKLGRPELEKLPLVFPQGDRELSTVLKQLETGINVV CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCEECCCCCHHHHHHHHHHHHCHHEE QSSSTGRVLDAASALLEICKIRTYDGEPAMKLESAAKKSTHVVDLPIVFKKYGGSGVPVL ECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECHHHHHCCCCCCCCE DTTELLLGAYELSGKYSPENLAFAVEESLAKGISELSLSLAAKRGLEKIGLSGGVAYNDH EHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEECHH ITSCIAGTVAEAGFEFLAHRQAPCGDGCISFGQAIAGGLRTDPESNQVPERV HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC >Mature Secondary Structure MQNESRLLHITGIVQGVGFRPFIYQLAKANGLSGYVKNLGNYVEILIEGDRECLDNFLKE CCCCCCEEEEEEEHHCCCCHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHH LPEKKPPLAKITELRTKNVPFSGYSGFIIVPSESGVFENSIIPPDTAICEQCRSEIFDPS CCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCC SRYYHYPFTVCTNCGPRYTTVRTLPYDRENTTMADFPLCPECEKEYTDPLNRRYHAQPVC CCEEECCEEEECCCCCCEEEEEECCCCCCCCEEECCCCCCCHHHHHCCHHHCCCCCCCCC CPKCGPEIWLSDREGNVLSRGYEAIASASDLLQEGSILAVKGFGGFHIACNARQEEPVNE CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHH LRRRLKRPEQPFAVMAKNAGVAESFADLEGAGREYLTSHRRPITVLPRSEEFNLADSVSP HHHHHCCCCCCCEEEECCCCCHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCCHHCCCC GLHNIGVMLPYTGTQNLLFDRVPDAVYVMTSANLPGRPMVVDNREALEKLKGIVDFYLLH CHHHCCEEEECCCCCHHHHHCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHH NRVIANRNDDTVIRIVNGQAAFIRRSRGYVPEPVELPFEIEASIGVGAEMNSTVTVAKGK HHHEECCCCCCEEEEECCCEEEHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCH LAYISQYIGNTSHVETYRYHSEVVRHLIRLTGIEPLHWSCDLHPSFNTTRFALKMGGENT HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCE LKIQHHYAHMLALMADNSLPLGSRILGIALDGVGYGGDGTIWGGELFESSYFGYERIGHL EEEHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCEECHHHHHHCCCCHHHHHHH LPQPMPGGDLASRVPSRMVLGILFEKLGRPELEKLPLVFPQGDRELSTVLKQLETGINVV CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCEECCCCCHHHHHHHHHHHHCHHEE QSSSTGRVLDAASALLEICKIRTYDGEPAMKLESAAKKSTHVVDLPIVFKKYGGSGVPVL ECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECHHHHHCCCCCCCCE DTTELLLGAYELSGKYSPENLAFAVEESLAKGISELSLSLAAKRGLEKIGLSGGVAYNDH EHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEECHH ITSCIAGTVAEAGFEFLAHRQAPCGDGCISFGQAIAGGLRTDPESNQVPERV HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]