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The map label for this gene is tfe [H]

Identifier: 21226794

GI number: 21226794

Start: 831128

End: 831622

Strand: Direct

Name: tfe [H]

Synonym: MM_0692

Alternate gene names: 21226794

Gene position: 831128-831622 (Clockwise)

Preceding gene: 21226793

Following gene: 21226795

Centisome position: 20.29

GC content: 43.03

Gene sequence:

>495_bases
TTGGTCGATTTAAATGACAAGGTAATTAGAGGATACCTCAGGAGCCTTGTAGGGGATGACGGGCTTAAAATGATAGAACA
GATGCCCGAAGGCAATGTCACGGATGAAGAAATTGCGGCGAAGACCGGAGTTCTGCTGAATACCGTGAGAAGAACTCTTT
TTATACTTTATGAGAATAAATTTGCAATAGTTGTAAGGGAAAGAGATTCAAATAGCGGATGGCTGACTTATCTCTGGCAT
CTGGACTTTTCCGACATAGAGCACCAGCTTATGAGGGAAAAGAAAAGACTGCTAAGGAATCTGAAGACCCGCCTTGAATT
TGAAGAAAATCATGTATTTTACGTTTGTCCTCAGGGTTGTGTTCGCCTTCTTTTTGACGAAGCAACGGAAACGGAATTTC
TCTGCCCAATGTGCGGAGAAGACCTGGTTTACTATGACAACTCCCGTTTTGTGGGAGTTCTGAAAAAGCGCGTAGAAGCT
TTGAGTTCCGCATAA

Upstream 100 bases:

>100_bases
GCAGTTTTTTCCGGACATGGAATCTTTTAAATAAAAATTTTAATGTAAGCTTTAATAATGGTATGTTCAATTCATATAAG
GGATTTGCGAGGTGAACACT

Downstream 100 bases:

>100_bases
GGGATTAATCTTGATCACCAGAGCCGAAGCGATCAGGTTTCTTGAGGAATCAGGCTGTGCCCCGAATGTGATTGAACACT
GCAAAGAGGTCGCCTCGCTT

Product: transcription initiation factor IIE subunit alpha

Products: NA

Alternate protein names: TFE; TFIIE subunit alpha homolog; Transcription initiation factor TFIIE [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MVDLNDKVIRGYLRSLVGDDGLKMIEQMPEGNVTDEEIAAKTGVLLNTVRRTLFILYENKFAIVVRERDSNSGWLTYLWH
LDFSDIEHQLMREKKRLLRNLKTRLEFEENHVFYVCPQGCVRLLFDEATETEFLCPMCGEDLVYYDNSRFVGVLKKRVEA
LSSA

Sequences:

>Translated_164_residues
MVDLNDKVIRGYLRSLVGDDGLKMIEQMPEGNVTDEEIAAKTGVLLNTVRRTLFILYENKFAIVVRERDSNSGWLTYLWH
LDFSDIEHQLMREKKRLLRNLKTRLEFEENHVFYVCPQGCVRLLFDEATETEFLCPMCGEDLVYYDNSRFVGVLKKRVEA
LSSA
>Mature_164_residues
MVDLNDKVIRGYLRSLVGDDGLKMIEQMPEGNVTDEEIAAKTGVLLNTVRRTLFILYENKFAIVVRERDSNSGWLTYLWH
LDFSDIEHQLMREKKRLLRNLKTRLEFEENHVFYVCPQGCVRLLFDEATETEFLCPMCGEDLVYYDNSRFVGVLKKRVEA
LSSA

Specific function: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (tbp), and transcription factor B (tfb) and RNA po

COG id: COG1675

COG function: function code K; Transcription initiation factor IIE, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH TFE/IIEalpha-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016481
- InterPro:   IPR017919
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 19145; Mature: 19145

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDLNDKVIRGYLRSLVGDDGLKMIEQMPEGNVTDEEIAAKTGVLLNTVRRTLFILYENK
CCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCC
FAIVVRERDSNSGWLTYLWHLDFSDIEHQLMREKKRLLRNLKTRLEFEENHVFYVCPQGC
EEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCEECCCCEEEECCHHH
VRLLFDEATETEFLCPMCGEDLVYYDNSRFVGVLKKRVEALSSA
HHHHHHCCCCCCEECCCCCCCEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDLNDKVIRGYLRSLVGDDGLKMIEQMPEGNVTDEEIAAKTGVLLNTVRRTLFILYENK
CCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCC
FAIVVRERDSNSGWLTYLWHLDFSDIEHQLMREKKRLLRNLKTRLEFEENHVFYVCPQGC
EEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCEECCCCEEEECCHHH
VRLLFDEATETEFLCPMCGEDLVYYDNSRFVGVLKKRVEALSSA
HHHHHHCCCCCCEECCCCCCCEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]