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The map label for this gene is 21226727

Identifier: 21226727

GI number: 21226727

Start: 756418

End: 757008

Strand: Direct

Name: 21226727

Synonym: MM_0625

Alternate gene names: NA

Gene position: 756418-757008 (Clockwise)

Preceding gene: 21226726

Following gene: 21226731

Centisome position: 18.47

GC content: 42.98

Gene sequence:

>591_bases
ATGCTCATAGGACTCACAGGTACGCCGGGAACAGGAAAAACCTCAGTAAGCAAACTTCTCGAAAAACGCAGGGGATGGAA
AGTGGTCTACCTTAATGATCTCATAAAGGAAGAACATCTGTACTCAGAAGTCGATGAAGAAAGGGACTCCGTAATTGCTG
ACATGGAACTCATCAGGGAGCGCCTTTCCGGCATTCTTGAAGAAGAAAAGGGACAGCATGCCGAAAAGGCAAAAGTAAAT
GGGGAGGAAAAGGAAAACATTACCATCATCGAAAGCCACCTTGCTCATTACATAACAGACATTGTAATAGTGCTCAGGGC
TTATCCTCCCGAACTGAAAAAAAGGCTTGAAAAACGAGGATATTCTGAAGAAAAAATTAACGAAAACGCAGAAGCCGAGT
CAATTGATTTGATCCTGGCAGAAGCTTTTGAATGGTGCAAAAAAGTCTTTGAAGTAAATACGACCGGCAGGACTGCAGAA
GAGACTTTGGGAGATGTGGAAAAGATTATAGATTATATTCTTGCTGGCAAAGAAAACGAACTGCAGGAATACATTCCGGG
CTCACTTGACTGGATTGATTCTGTGCCCTGA

Upstream 100 bases:

>100_bases
CGAATAGCCGATAGACACAGGCACTGGTACAGAAATCCCAGCACTCAGATTTTTCAGGGCGGCATTAAGTATAACTCCGA
TAAACCCTATCTCCTCCTCC

Downstream 100 bases:

>100_bases
AAGATACTCTAAAAACCATAAGAAGCTTAAAAGAAGATTATTGCATAAAAATGGTCATAAAGAAAAATTGCTGTCACTGG
TAGAAACATTCTTCAGACGG

Product: hypothetical protein

Products: NA

Alternate protein names: ATP-AMP transphosphorylase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLIGLTGTPGTGKTSVSKLLEKRRGWKVVYLNDLIKEEHLYSEVDEERDSVIADMELIRERLSGILEEEKGQHAEKAKVN
GEEKENITIIESHLAHYITDIVIVLRAYPPELKKRLEKRGYSEEKINENAEAESIDLILAEAFEWCKKVFEVNTTGRTAE
ETLGDVEKIIDYILAGKENELQEYIPGSLDWIDSVP

Sequences:

>Translated_196_residues
MLIGLTGTPGTGKTSVSKLLEKRRGWKVVYLNDLIKEEHLYSEVDEERDSVIADMELIRERLSGILEEEKGQHAEKAKVN
GEEKENITIIESHLAHYITDIVIVLRAYPPELKKRLEKRGYSEEKINENAEAESIDLILAEAFEWCKKVFEVNTTGRTAE
ETLGDVEKIIDYILAGKENELQEYIPGSLDWIDSVP
>Mature_196_residues
MLIGLTGTPGTGKTSVSKLLEKRRGWKVVYLNDLIKEEHLYSEVDEERDSVIADMELIRERLSGILEEEKGQHAEKAKVN
GEEKENITIIESHLAHYITDIVIVLRAYPPELKKRLEKRGYSEEKINENAEAESIDLILAEAFEWCKKVFEVNTTGRTAE
ETLGDVEKIIDYILAGKENELQEYIPGSLDWIDSVP

Specific function: Unknown

COG id: COG1936

COG function: function code F; Predicted nucleotide kinase (related to CMP and AMP kinases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenylate kinase family. AK6 subfamily

Homologues:

Organism=Homo sapiens, GI7706212, Length=175, Percent_Identity=30.8571428571429, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI62865612, Length=171, Percent_Identity=29.8245614035088, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532769, Length=146, Percent_Identity=28.0821917808219, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320035, Length=173, Percent_Identity=27.7456647398844, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KAD6_METMA (Q8PZ69)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_632649.1
- ProteinModelPortal:   Q8PZ69
- SMR:   Q8PZ69
- GeneID:   1478967
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0625
- NMPDR:   fig|192952.1.peg.625
- HOGENOM:   HBG646389
- OMA:   RVGIVDW
- ProtClustDB:   CLSK450466
- BioCyc:   MMAZ192952:MM0625-MONOMER
- BRENDA:   2.7.4.3
- HAMAP:   MF_00039
- InterPro:   IPR020618

Pfam domain/function: NA

EC number: =2.7.4.3

Molecular weight: Translated: 22344; Mature: 22344

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGLTGTPGTGKTSVSKLLEKRRGWKVVYLNDLIKEEHLYSEVDEERDSVIADMELIRE
CEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSGILEEEKGQHAEKAKVNGEEKENITIIESHLAHYITDIVIVLRAYPPELKKRLEKRG
HHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
YSEEKINENAEAESIDLILAEAFEWCKKVFEVNTTGRTAEETLGDVEKIIDYILAGKENE
CCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
LQEYIPGSLDWIDSVP
HHHHCCCCCCHHCCCC
>Mature Secondary Structure
MLIGLTGTPGTGKTSVSKLLEKRRGWKVVYLNDLIKEEHLYSEVDEERDSVIADMELIRE
CEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSGILEEEKGQHAEKAKVNGEEKENITIIESHLAHYITDIVIVLRAYPPELKKRLEKRG
HHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
YSEEKINENAEAESIDLILAEAFEWCKKVFEVNTTGRTAEETLGDVEKIIDYILAGKENE
CCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
LQEYIPGSLDWIDSVP
HHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824