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The map label for this gene is slyD [C]

Identifier: 21226483

GI number: 21226483

Start: 487779

End: 488279

Strand: Reverse

Name: slyD [C]

Synonym: MM_0381

Alternate gene names: 21226483

Gene position: 488279-487779 (Counterclockwise)

Preceding gene: 21226484

Following gene: 21226482

Centisome position: 11.92

GC content: 46.91

Gene sequence:

>501_bases
ATGGTTTTAGGAAGCGGATGCACGGATAACGGCAGCGGAGACGGCAGGGCTGTAAAAGCAGGAGATACGGTCCAGGTAGA
TTATGTGGGAAAATTTGAGAATGGCACCGTTTTTGATACTTCTATAGAAGAAGAAGCACAGGAAGCAGGCATATACAATG
CACAGAGAGAGTATGTACCCCTGAACCTTACTGCTGGTTCCGGCCAGGTAATTGAGGGTTTTGATGAAGGGCTGATAGGA
ATGAAGGAGGGCGAAGAGAAAACCCTGACTATTCCTCCTGAGAAAGCCTATGGGGAATACAATGAAAGCTGGGTTCAGGC
AGTCCCTCTTGAAGAGCTCAATATGTCAGAAAAGCCTGAAGTAGGGCAGGTATACAGCAGCATATACGGAGGCCAGTTTA
AAGTCATTGCCGTAAATGAGACGCACGTTACTTTTGACCCTAACCATGAACTCGCAGGCGAGACTCTTGTTTTCGATGTA
AAGCTCGTATCAATCGAGTGA

Upstream 100 bases:

>100_bases
CCCTTACATTCAAAGTAAAGGTCATTTCAGTGGAGGAATGAAAAAAATGAGGGTCGGGAAGAGTACAATATATTTCCTGA
CAATGCTGCTTCTGGCAAGT

Downstream 100 bases:

>100_bases
TGTTAAGTTAATTGAACCGGTCCAGAACCGGTTTATATTTCTTTAATTAGATTCATCTGTCCGGCATTCCGGAATTTTTC
CTGGCTGCCGGAAAAGCTTC

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MVLGSGCTDNGSGDGRAVKAGDTVQVDYVGKFENGTVFDTSIEEEAQEAGIYNAQREYVPLNLTAGSGQVIEGFDEGLIG
MKEGEEKTLTIPPEKAYGEYNESWVQAVPLEELNMSEKPEVGQVYSSIYGGQFKVIAVNETHVTFDPNHELAGETLVFDV
KLVSIE

Sequences:

>Translated_166_residues
MVLGSGCTDNGSGDGRAVKAGDTVQVDYVGKFENGTVFDTSIEEEAQEAGIYNAQREYVPLNLTAGSGQVIEGFDEGLIG
MKEGEEKTLTIPPEKAYGEYNESWVQAVPLEELNMSEKPEVGQVYSSIYGGQFKVIAVNETHVTFDPNHELAGETLVFDV
KLVSIE
>Mature_166_residues
MVLGSGCTDNGSGDGRAVKAGDTVQVDYVGKFENGTVFDTSIEEEAQEAGIYNAQREYVPLNLTAGSGQVIEGFDEGLIG
MKEGEEKTLTIPPEKAYGEYNESWVQAVPLEELNMSEKPEVGQVYSSIYGGQFKVIAVNETHVTFDPNHELAGETLVFDV
KLVSIE

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=81, Percent_Identity=40.7407407407407, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI17149844, Length=81, Percent_Identity=40.7407407407407, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI17149842, Length=81, Percent_Identity=40.7407407407407, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI4503727, Length=81, Percent_Identity=44.4444444444444, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356629, Length=79, Percent_Identity=41.7721518987342, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17960; Mature: 17960

Theoretical pI: Translated: 3.89; Mature: 3.89

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLGSGCTDNGSGDGRAVKAGDTVQVDYVGKFENGTVFDTSIEEEAQEAGIYNAQREYVP
CEECCCCCCCCCCCCEEEECCCEEEEEEEEECCCCEEEECCHHHHHHHCCCCCCCCCEEE
LNLTAGSGQVIEGFDEGLIGMKEGEEKTLTIPPEKAYGEYNESWVQAVPLEELNMSEKPE
EEEECCCCCEEECCCCCCEECCCCCCCEEEECCHHHCCCCCCCEEEECCHHHCCCCCCCC
VGQVYSSIYGGQFKVIAVNETHVTFDPNHELAGETLVFDVKLVSIE
HHHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure
MVLGSGCTDNGSGDGRAVKAGDTVQVDYVGKFENGTVFDTSIEEEAQEAGIYNAQREYVP
CEECCCCCCCCCCCCEEEECCCEEEEEEEEECCCCEEEECCHHHHHHHCCCCCCCCCEEE
LNLTAGSGQVIEGFDEGLIGMKEGEEKTLTIPPEKAYGEYNESWVQAVPLEELNMSEKPE
EEEECCCCCEEECCCCCCEECCCCCCCEEEECCHHHCCCCCCCEEEECCHHHCCCCCCCC
VGQVYSSIYGGQFKVIAVNETHVTFDPNHELAGETLVFDVKLVSIE
HHHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]