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The map label for this gene is fkpB [C]

Identifier: 21226482

GI number: 21226482

Start: 487168

End: 487650

Strand: Reverse

Name: fkpB [C]

Synonym: MM_0380

Alternate gene names: 21226482

Gene position: 487650-487168 (Counterclockwise)

Preceding gene: 21226483

Following gene: 21226481

Centisome position: 11.9

GC content: 45.34

Gene sequence:

>483_bases
ATGGAGAACCCCCGGACTGTAAAAAAGGGAGATTATGTCCTTATTGATTACACTGGAAAATTTGAAAATGGAACGGTATT
TGACACCACTCTAAAAGAGAAAGCTCTTGAGGCCGGAATATATGGTGAAGAAAAGGACTACAGGCCTTTCTTTTTCAGGA
CAGATACCCGGCAGGTGATAAAAGGCATTGATGAAGGCGTCCTTGGGATGCGGGAAGGAGAAGAAAAAACCCTTAAAATA
CCTCCCGCAGAAGCCTACGGAGAACATAAAGATTATCTCGTCCAGAAAATCCCTCTTCTCCGGCTTGAACTGAAAGAGCC
TCCGGAGCCGGGAAAGACAATCATAACCCCCGGAGGAAGGATAGTTAAGGTGCTTAACTCCACGGAAACTTACGCAATCC
TTGACTTTAACCATGAGCTTGCAGGCAAAACCCTGATCCTTGAAATAAAGCTCGTCTCCATCGTGAACAGGCCTGAAATG
TGA

Upstream 100 bases:

>100_bases
CGGTTTATATTTCTTTAATTAGATTCATCTGTCCGGCATTCCGGAATTTTTCCTGGCTGCCGGAAAAGCTTCAGAGAAAA
AAATAACAGGAGAAGGGAGA

Downstream 100 bases:

>100_bases
GCCGATCCCTGAATAAAACGTAAAGCGGTTCCGGGATACAGAGTCCGGAATGTATAACCTGCATGAAATATAAAGATGCG
AAATTCTACTCATCCTGAGG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MENPRTVKKGDYVLIDYTGKFENGTVFDTTLKEKALEAGIYGEEKDYRPFFFRTDTRQVIKGIDEGVLGMREGEEKTLKI
PPAEAYGEHKDYLVQKIPLLRLELKEPPEPGKTIITPGGRIVKVLNSTETYAILDFNHELAGKTLILEIKLVSIVNRPEM

Sequences:

>Translated_160_residues
MENPRTVKKGDYVLIDYTGKFENGTVFDTTLKEKALEAGIYGEEKDYRPFFFRTDTRQVIKGIDEGVLGMREGEEKTLKI
PPAEAYGEHKDYLVQKIPLLRLELKEPPEPGKTIITPGGRIVKVLNSTETYAILDFNHELAGKTLILEIKLVSIVNRPEM
>Mature_160_residues
MENPRTVKKGDYVLIDYTGKFENGTVFDTTLKEKALEAGIYGEEKDYRPFFFRTDTRQVIKGIDEGVLGMREGEEKTLKI
PPAEAYGEHKDYLVQKIPLLRLELKEPPEPGKTIITPGGRIVKVLNSTETYAILDFNHELAGKTLILEIKLVSIVNRPEM

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=85, Percent_Identity=43.5294117647059, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI17149844, Length=85, Percent_Identity=43.5294117647059, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI17149842, Length=85, Percent_Identity=43.5294117647059, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18170; Mature: 18170

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENPRTVKKGDYVLIDYTGKFENGTVFDTTLKEKALEAGIYGEEKDYRPFFFRTDTRQVI
CCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHH
KGIDEGVLGMREGEEKTLKIPPAEAYGEHKDYLVQKIPLLRLELKEPPEPGKTIITPGGR
HHCCCCCCCCCCCCCCEEECCCHHHCCCCHHHHHHHCCEEEEEECCCCCCCCEEECCCCE
IVKVLNSTETYAILDFNHELAGKTLILEIKLVSIVNRPEM
EEEEECCCCEEEEEECCCCCCCCEEEEEEEEEEEECCCCC
>Mature Secondary Structure
MENPRTVKKGDYVLIDYTGKFENGTVFDTTLKEKALEAGIYGEEKDYRPFFFRTDTRQVI
CCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHH
KGIDEGVLGMREGEEKTLKIPPAEAYGEHKDYLVQKIPLLRLELKEPPEPGKTIITPGGR
HHCCCCCCCCCCCCCCEEECCCHHHCCCCHHHHHHHCCEEEEEECCCCCCCCEEECCCCE
IVKVLNSTETYAILDFNHELAGKTLILEIKLVSIVNRPEM
EEEEECCCCEEEEEECCCCCCCCEEEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]