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The map label for this gene is ribH [H]

Identifier: 21226346

GI number: 21226346

Start: 326679

End: 327083

Strand: Reverse

Name: ribH [H]

Synonym: MM_0244

Alternate gene names: 21226346

Gene position: 327083-326679 (Counterclockwise)

Preceding gene: 21226347

Following gene: 21226345

Centisome position: 7.98

GC content: 50.37

Gene sequence:

>405_bases
ATGACTATCAGCCTAGGATTTGTTGTAGCTGAATTTAACAGGGATCTTACCTATCAGATGGAGCTGCTTGGAAGAGAGCA
TGCAGAGTTCCTTGGGGCAACAGTTAAAGAGACTATTCTCGTGCCCGGGGTCTTTGATATGCCTCTTGCAATCAAAAAGC
TCTGCCAGAGGGAAGATATTGATGCAGTGGTTACCATAGGGTCGGTAATCGAAGGCGAAACCGACCATGACCAGGTGGTT
ATGCAGCATGCCGCAAGAAAGATTATGGATCTTTCCCTTGAGTTCAACAAGCCGGTAACTCTTGGAATCCCCGGCCCGGG
TATGACCAGGATGGCCGCACATGAACGTGTCGACTATGCCAAAAGGGCTGTCGAAGCTGCGGTAAAGCTGGTGCGGCGGC
TGTGA

Upstream 100 bases:

>100_bases
GGCACCGGTCAAAGACAGGGGTTTGAAGATGCAGGCCCTTTAAGAATGTGATGTGACTTTAGTAACTTTAAATTAAAAAC
AAGACTGGAGACCTTATTCG

Downstream 100 bases:

>100_bases
AATTCTTTAACGTCTGATAAGCTAGCAAAATGTAATAAACCAGGACCATCCCTATGACATCCGCAAGGCTTAAGCGTGTA
GAAGAATCCGCAACGATCAG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MTISLGFVVAEFNRDLTYQMELLGREHAEFLGATVKETILVPGVFDMPLAIKKLCQREDIDAVVTIGSVIEGETDHDQVV
MQHAARKIMDLSLEFNKPVTLGIPGPGMTRMAAHERVDYAKRAVEAAVKLVRRL

Sequences:

>Translated_134_residues
MTISLGFVVAEFNRDLTYQMELLGREHAEFLGATVKETILVPGVFDMPLAIKKLCQREDIDAVVTIGSVIEGETDHDQVV
MQHAARKIMDLSLEFNKPVTLGIPGPGMTRMAAHERVDYAKRAVEAAVKLVRRL
>Mature_133_residues
TISLGFVVAEFNRDLTYQMELLGREHAEFLGATVKETILVPGVFDMPLAIKKLCQREDIDAVVTIGSVIEGETDHDQVVM
QHAARKIMDLSLEFNKPVTLGIPGPGMTRMAAHERVDYAKRAVEAAVKLVRRL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 14892; Mature: 14760

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISLGFVVAEFNRDLTYQMELLGREHAEFLGATVKETILVPGVFDMPLAIKKLCQREDI
CEEEHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCC
DAVVTIGSVIEGETDHDQVVMQHAARKIMDLSLEFNKPVTLGIPGPGMTRMAAHERVDYA
HHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHH
KRAVEAAVKLVRRL
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TISLGFVVAEFNRDLTYQMELLGREHAEFLGATVKETILVPGVFDMPLAIKKLCQREDI
EEEHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCC
DAVVTIGSVIEGETDHDQVVMQHAARKIMDLSLEFNKPVTLGIPGPGMTRMAAHERVDYA
HHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHH
KRAVEAAVKLVRRL
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]