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The map label for this gene is cbiZ

Identifier: 21226275

GI number: 21226275

Start: 230669

End: 231271

Strand: Direct

Name: cbiZ

Synonym: MM_0173

Alternate gene names: 21226275

Gene position: 230669-231271 (Clockwise)

Preceding gene: 21226269

Following gene: 21226276

Centisome position: 5.63

GC content: 42.79

Gene sequence:

>603_bases
ATGCAATATCACATAAAAGACCAGACACTCATTATAAAAGGTGATTTTGAAGCCGTAAGCACCGGATTAAACGGCGGCCG
TGCGCGGGTAGAATACATTTTTAATAAACAGGTGCCAAGGACTTTTAATCCCCCAAGTCCTGAGGAGTTCATAAGAGAAG
AAGCTCGAAAAGACGGAATAGAAACAGCCAGTCTCGGTCTTCTGACAGCAGTAAATATGGAATACCTCCAGGTCATTGAA
GACGATTATATGACAGCTTTTATAACAGCTGGCGTAAGCAACTGCTCGGAATTCAGGGCAAAGGCAGGGACCATAAACAT
AATTCTGGTCTCAAAAGCAAGGCTATCAGAAACAGCTCTCTTCGGTGCAATCATCACAGCTACTGAAGCTAAAGGGCTTG
CTCTTCTCGAAAAAGGATACAATTTTCTGGGCACCAATACGGATGCAGTTATTGTTGCATATGAGACCTGCTCAGACTCG
GGCCCGAAAAGTAAGACAAATCAGGAAATCCCTTATGCAGGTTCAAGTACTGAGTTTGGAAAAAAGATTACAGAAGCAGT
TATAAAAGGGATTAAGGCAGGGCTTGAGTTAAGAGGAGAATAA

Upstream 100 bases:

>100_bases
AACCTTATGTAACGAGTTTGGAAAATATTATCTCACAATATTATCTCGCAACTCGCCACCTATATGAAATATACATCCTC
TTTAAAAACGGAGCCCTTAC

Downstream 100 bases:

>100_bases
AACAAAACTGTTTTCGTATACAATATAAATGAATCTAATTTCCCACCACTTCTGCCCTATTTAATATACTGTGAGGTGCA
CGCTCTTTAGATCTGAAAAC

Product: transporter

Products: NA

Alternate protein names: AdoCbi hydrolase

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MQYHIKDQTLIIKGDFEAVSTGLNGGRARVEYIFNKQVPRTFNPPSPEEFIREEARKDGIETASLGLLTAVNMEYLQVIE
DDYMTAFITAGVSNCSEFRAKAGTINIILVSKARLSETALFGAIITATEAKGLALLEKGYNFLGTNTDAVIVAYETCSDS
GPKSKTNQEIPYAGSSTEFGKKITEAVIKGIKAGLELRGE

Sequences:

>Translated_200_residues
MQYHIKDQTLIIKGDFEAVSTGLNGGRARVEYIFNKQVPRTFNPPSPEEFIREEARKDGIETASLGLLTAVNMEYLQVIE
DDYMTAFITAGVSNCSEFRAKAGTINIILVSKARLSETALFGAIITATEAKGLALLEKGYNFLGTNTDAVIVAYETCSDS
GPKSKTNQEIPYAGSSTEFGKKITEAVIKGIKAGLELRGE
>Mature_200_residues
MQYHIKDQTLIIKGDFEAVSTGLNGGRARVEYIFNKQVPRTFNPPSPEEFIREEARKDGIETASLGLLTAVNMEYLQVIE
DDYMTAFITAGVSNCSEFRAKAGTINIILVSKARLSETALFGAIITATEAKGLALLEKGYNFLGTNTDAVIVAYETCSDS
GPKSKTNQEIPYAGSSTEFGKKITEAVIKGIKAGLELRGE

Specific function: Converts adenosylcobinamide (AdoCbi) to adenosylcobyric acid (AdoCby), an intermediate of the de novo coenzyme B12 biosynthetic route

COG id: COG1865

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiZ family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIZ_METMA (Q8Q0G3)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_632197.1
- GeneID:   1478515
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0173
- NMPDR:   fig|192952.1.peg.173
- HOGENOM:   HBG541645
- OMA:   PRTFNPP
- ProtClustDB:   CLSK541727
- BioCyc:   MetaCyc:MONOMER-14880
- BioCyc:   MMAZ192952:MM0173-MONOMER
- BRENDA:   3.5.1.90
- InterPro:   IPR002808

Pfam domain/function: PF01955 CbiZ

EC number: =3.5.1.90

Molecular weight: Translated: 21713; Mature: 21713

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYHIKDQTLIIKGDFEAVSTGLNGGRARVEYIFNKQVPRTFNPPSPEEFIREEARKDGI
CCEEECCCEEEEEECHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
ETASLGLLTAVNMEYLQVIEDDYMTAFITAGVSNCSEFRAKAGTINIILVSKARLSETAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCHHHHHHH
FGAIITATEAKGLALLEKGYNFLGTNTDAVIVAYETCSDSGPKSKTNQEIPYAGSSTEFG
HHHHEECCCCCCHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
KKITEAVIKGIKAGLELRGE
HHHHHHHHHHHHHCCEECCC
>Mature Secondary Structure
MQYHIKDQTLIIKGDFEAVSTGLNGGRARVEYIFNKQVPRTFNPPSPEEFIREEARKDGI
CCEEECCCEEEEEECHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
ETASLGLLTAVNMEYLQVIEDDYMTAFITAGVSNCSEFRAKAGTINIILVSKARLSETAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCHHHHHHH
FGAIITATEAKGLALLEKGYNFLGTNTDAVIVAYETCSDSGPKSKTNQEIPYAGSSTEFG
HHHHEECCCCCCHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
KKITEAVIKGIKAGLELRGE
HHHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824