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The map label for this gene is comEB [H]

Identifier: 212224519

GI number: 212224519

Start: 1238308

End: 1238853

Strand: Reverse

Name: comEB [H]

Synonym: TON_1368

Alternate gene names: 212224519

Gene position: 1238853-1238308 (Counterclockwise)

Preceding gene: 212224520

Following gene: 212224516

Centisome position: 67.05

GC content: 53.66

Gene sequence:

>546_bases
ATGGCTATGAGCGTTGAAATCTTCCTAGACCGGGAAAAGGCAGCGCGCATAAAGCGCATCAGGCCAACCAAGGACGAGTA
CTTTATGCTGATAGCGAAACTTGTGAGCCTTAGAGCAACCTGTCCAAGGCTCCGCGTTGGCGCCGTTGCCGTCAAGGACG
GGTACATACTTGCAACAGGCTACAACGGTGCGCCGAGGGGAATGGAGCACTGTATTGATGTAGGCTGCCTCATAGTGGAC
GGCCACTGCCACAGGGCGGTTCACGCGGAGCAGAACGTCATAGCCATGGCAGCCAGAAAGGGCATAAGCCTCGAGGGGGC
AACTCTCTACGTCACCCACTTCCCCTGCGACACCTGCTTCAAGTTAGTCATCAACGCAGGCATAAAGGAGATAGTATACG
AGGAAATGTACCCCAACGAGGCAACTGAAGTACTCCTCAGGGAAGCACAGGAGAAAGGAATAGTGAAGATAAGGCAGTTC
AGACTCCCGAAAGAGAGGGTGAAGCTCTTCCTGGAGGAGCTCTTCGGAGAGTTTGTGGAGGATTAA

Upstream 100 bases:

>100_bases
AAACAGCCATAATAGAGACCCATCCAAGTTATGATGAGAGAATATTCAGAATCTTGGTTGAAATAAATGGTAGTAACCTG
TTCAACAGGCGCATGCAGTG

Downstream 100 bases:

>100_bases
AGGTTCTTCTCTATTTTTTCCAGTCGCTTGTTTATCTCCTCCAGCTCCATGGCGATTTTCCTTGTTAGCTCGGTTATCTC
GCGCTCGGTTTTGTCGACAG

Product: deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAMSVEIFLDREKAARIKRIRPTKDEYFMLIAKLVSLRATCPRLRVGAVAVKDGYILATGYNGAPRGMEHCIDVGCLIVD
GHCHRAVHAEQNVIAMAARKGISLEGATLYVTHFPCDTCFKLVINAGIKEIVYEEMYPNEATEVLLREAQEKGIVKIRQF
RLPKERVKLFLEELFGEFVED

Sequences:

>Translated_181_residues
MAMSVEIFLDREKAARIKRIRPTKDEYFMLIAKLVSLRATCPRLRVGAVAVKDGYILATGYNGAPRGMEHCIDVGCLIVD
GHCHRAVHAEQNVIAMAARKGISLEGATLYVTHFPCDTCFKLVINAGIKEIVYEEMYPNEATEVLLREAQEKGIVKIRQF
RLPKERVKLFLEELFGEFVED
>Mature_180_residues
AMSVEIFLDREKAARIKRIRPTKDEYFMLIAKLVSLRATCPRLRVGAVAVKDGYILATGYNGAPRGMEHCIDVGCLIVDG
HCHRAVHAEQNVIAMAARKGISLEGATLYVTHFPCDTCFKLVINAGIKEIVYEEMYPNEATEVLLREAQEKGIVKIRQFR
LPKERVKLFLEELFGEFVED

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=116, Percent_Identity=36.2068965517241, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI61742821, Length=116, Percent_Identity=36.2068965517241, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17557019, Length=148, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321938, Length=172, Percent_Identity=34.8837209302326, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24667298, Length=129, Percent_Identity=34.8837209302326, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667302, Length=129, Percent_Identity=34.8837209302326, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20458; Mature: 20327

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMSVEIFLDREKAARIKRIRPTKDEYFMLIAKLVSLRATCPRLRVGAVAVKDGYILATG
CCEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEECEEEEECCEEEEEC
YNGAPRGMEHCIDVGCLIVDGHCHRAVHAEQNVIAMAARKGISLEGATLYVTHFPCDTCF
CCCCCHHHHHHHHHCEEEECCCCHHHHHCCCHHHHHHHHCCCCCCCCEEEEEECCHHHHH
KLVINAGIKEIVYEEMYPNEATEVLLREAQEKGIVKIRQFRLPKERVKLFLEELFGEFVE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHC
D
C
>Mature Secondary Structure 
AMSVEIFLDREKAARIKRIRPTKDEYFMLIAKLVSLRATCPRLRVGAVAVKDGYILATG
CEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEECEEEEECCEEEEEC
YNGAPRGMEHCIDVGCLIVDGHCHRAVHAEQNVIAMAARKGISLEGATLYVTHFPCDTCF
CCCCCHHHHHHHHHCEEEECCCCHHHHHCCCHHHHHHHHCCCCCCCCEEEEEECCHHHHH
KLVINAGIKEIVYEEMYPNEATEVLLREAQEKGIVKIRQFRLPKERVKLFLEELFGEFVE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]