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The map label for this gene is htpX [H]

Identifier: 212224520

GI number: 212224520

Start: 1238853

End: 1239635

Strand: Reverse

Name: htpX [H]

Synonym: TON_1369

Alternate gene names: 212224520

Gene position: 1239635-1238853 (Counterclockwise)

Preceding gene: 212224521

Following gene: 212224519

Centisome position: 67.09

GC content: 49.68

Gene sequence:

>783_bases
ATGCTCTTCATCATAATAACCCTAGAGGTCCTGCTGGCAGTAGTGGCCCTAAAAGAACTGGGCCTCAAGATATCACTGAC
GGCATTTGGCCTCATCTTCGCATTCTATCTCTGGGTCTCCACCCACGACATCAAGGGTAACTATATCCCCCTTGAAAGAA
GTGAGATCCCCTGGCTCTACGACGGCATAGCCAGAATGGCAAAGAAGGCAGGCCTCTCAATGCCAAGGGTTTACATCCTT
GACGACTACATCCCAAACGCATACTCATTTAAGAACACGGTGGTCCTTTCCCTCGGACTTTTCGAGGTTCTTGACCAAGA
CGAAATACTAGCCGTTGCCGCCCATGAACTCGGCCACATAAAGAATGGCGACACAAAGATGTTTCCCATTATAGCCTACG
GCAGGTACCTTATGATTGTGTTCACAGCGGTGCTGATTTTCCTAGCCCACAGCCCCACTGTCACAATAGCAGCACTCGGA
CTATACGGACTCTACGAGGTTACCCGCGCTAGCTTCCTGAAGAACAGGGAATTCCAGGCGGACGAAACCGCACTCAGACT
CTTAGACGTCCCTATGAGCCTGAAGCGCGCCCTTGAGGAGCTTAAATACTACGAGGATCTCAGGATAGGAGTCAGGCTGA
GCTCGCTGCCGAGCATTGAGCCGGCAATAGAGAGGAAGCAGAAAACAGCCATAATAGAGACCCATCCAAGTTATGATGAG
AGAATATTCAGAATCTTGGTTGAAATAAATGGTAGTAACCTGTTCAACAGGCGCATGCAGTGA

Upstream 100 bases:

>100_bases
GTTCGAGGAAAAAGTAGTGAAGAGTATCCTCGACGCCCTCATGACAAACTTCAGGGAAGCGACCTACGCATACCTCTCCA
AAATTAAGAAGTGATGAAAG

Downstream 100 bases:

>100_bases
TGGCTATGAGCGTTGAAATCTTCCTAGACCGGGAAAAGGCAGCGCGCATAAAGCGCATCAGGCCAACCAAGGACGAGTAC
TTTATGCTGATAGCGAAACT

Product: zinc-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLFIIITLEVLLAVVALKELGLKISLTAFGLIFAFYLWVSTHDIKGNYIPLERSEIPWLYDGIARMAKKAGLSMPRVYIL
DDYIPNAYSFKNTVVLSLGLFEVLDQDEILAVAAHELGHIKNGDTKMFPIIAYGRYLMIVFTAVLIFLAHSPTVTIAALG
LYGLYEVTRASFLKNREFQADETALRLLDVPMSLKRALEELKYYEDLRIGVRLSSLPSIEPAIERKQKTAIIETHPSYDE
RIFRILVEINGSNLFNRRMQ

Sequences:

>Translated_260_residues
MLFIIITLEVLLAVVALKELGLKISLTAFGLIFAFYLWVSTHDIKGNYIPLERSEIPWLYDGIARMAKKAGLSMPRVYIL
DDYIPNAYSFKNTVVLSLGLFEVLDQDEILAVAAHELGHIKNGDTKMFPIIAYGRYLMIVFTAVLIFLAHSPTVTIAALG
LYGLYEVTRASFLKNREFQADETALRLLDVPMSLKRALEELKYYEDLRIGVRLSSLPSIEPAIERKQKTAIIETHPSYDE
RIFRILVEINGSNLFNRRMQ
>Mature_260_residues
MLFIIITLEVLLAVVALKELGLKISLTAFGLIFAFYLWVSTHDIKGNYIPLERSEIPWLYDGIARMAKKAGLSMPRVYIL
DDYIPNAYSFKNTVVLSLGLFEVLDQDEILAVAAHELGHIKNGDTKMFPIIAYGRYLMIVFTAVLIFLAHSPTVTIAALG
LYGLYEVTRASFLKNREFQADETALRLLDVPMSLKRALEELKYYEDLRIGVRLSSLPSIEPAIERKQKTAIIETHPSYDE
RIFRILVEINGSNLFNRRMQ

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=249, Percent_Identity=26.5060240963855, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 29591; Mature: 29591

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFIIITLEVLLAVVALKELGLKISLTAFGLIFAFYLWVSTHDIKGNYIPLERSEIPWLY
CEEEEEHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHH
DGIARMAKKAGLSMPRVYILDDYIPNAYSFKNTVVLSLGLFEVLDQDEILAVAAHELGHI
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHCCC
KNGDTKMFPIIAYGRYLMIVFTAVLIFLAHSPTVTIAALGLYGLYEVTRASFLKNREFQA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DETALRLLDVPMSLKRALEELKYYEDLRIGVRLSSLPSIEPAIERKQKTAIIETHPSYDE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCEEEECCCCHHH
RIFRILVEINGSNLFNRRMQ
HHHHHEEEECCCHHHHCCCC
>Mature Secondary Structure
MLFIIITLEVLLAVVALKELGLKISLTAFGLIFAFYLWVSTHDIKGNYIPLERSEIPWLY
CEEEEEHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHH
DGIARMAKKAGLSMPRVYILDDYIPNAYSFKNTVVLSLGLFEVLDQDEILAVAAHELGHI
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHCCC
KNGDTKMFPIIAYGRYLMIVFTAVLIFLAHSPTVTIAALGLYGLYEVTRASFLKNREFQA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DETALRLLDVPMSLKRALEELKYYEDLRIGVRLSSLPSIEPAIERKQKTAIIETHPSYDE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCEEEECCCCHHH
RIFRILVEINGSNLFNRRMQ
HHHHHEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA