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The map label for this gene is gnpTA [H]

Identifier: 212224516

GI number: 212224516

Start: 1235654

End: 1236562

Strand: Reverse

Name: gnpTA [H]

Synonym: TON_1365

Alternate gene names: 212224516

Gene position: 1236562-1235654 (Counterclockwise)

Preceding gene: 212224519

Following gene: 212224514

Centisome position: 66.93

GC content: 48.95

Gene sequence:

>909_bases
ATGATAGTCGTTGCTCCTCTTATAGGTTTAACTCTGACACTCATCATGACGCCATACATCGCGGAAAGGATGAGAAGAGC
CGGCATTGTCGGGAGGGACATCCACAAGCTTGACCAGCCAGAAGTGCCGGAGATGGGGGGGATCGCTCTTATCCTGGCCC
TGCCAGTTGCACTTTCGCCGTTTTTAACCGAGAAGATTTCCCTGGCGACAACGGTGTTTCTCCTTTTCGGAATTATCGGC
GTTGTTGATGATCTAACCAATCTGAGGCAGCTTCACAAGGTCATTCTCTCACTTTTCGTATCAATCCCAGTTGCCGTCAT
AGGAGTTTCATCCCATATCGATATCTTCGGCTTTGACCTGAATCTCGGGGTACTCTATCCCATCTTTGCCGTGCTCTTTG
TAACAGGTTCAGCCAACTTGGTGAATATGCTTGCTGGATTCAACGGACTCGAGATCGGCACCTCCACCATAGCACTTCTT
TTCCTAGCACTGATAACAGACGGAAATGCTCAACTGCTTGCACTTACTGGTCTCGGCGCGGCTCTCGGCTTCCTGCGTTG
GAACAAGTATCCAGCGAAAGTCTTTCCCGGCGACACGGGAACGCTCAGCATGGGGGCACTTATAGGATTAATAGGGATTA
TTGGAAAAGTCGAGGTTTATACTGCAATACTCCTGATTCCACACTTTTTGGACTTCATCATAAAGGCAACAAGTGTACGC
TTTGGGGTGAGAAGACACGGAAAAACTAAAGTCCTCCCGGACGGGACGCTCCAAGCACCACCTTATCCGAGCTTTTTGGG
GACGATAATGAGAAAAATAAGAGTGAACGAGCCGAAGCTTGTCGCGATAGTCTGGCTGGTAGAGGCTACTCTTGGTCTTC
TCGTCTTAGTTCTTCGTCAATCACTTTGA

Upstream 100 bases:

>100_bases
GATGAGGGTTCCGTCGAGGTCAAAGACAACGAGCCTTATATCCATGGTCTTCACCGAAGGGTTTATTTTTGGGCCGTTGT
AACACCGAGGGGTGTCTAAT

Downstream 100 bases:

>100_bases
CCATACCAAAGCCATATCTGGTTTTTTCTCCAAAGCCGTTCTCATAGCCGAAGCGAGCTATCTCGAGGGAGCCGCGATAG
CGGAATATCATCAGAGAGCC

Product: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Products: NA

Alternate protein names: GlcNAc-1-P transferase; G1PT; GPT; N-acetylglucosamine-1-phosphate transferase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MIVVAPLIGLTLTLIMTPYIAERMRRAGIVGRDIHKLDQPEVPEMGGIALILALPVALSPFLTEKISLATTVFLLFGIIG
VVDDLTNLRQLHKVILSLFVSIPVAVIGVSSHIDIFGFDLNLGVLYPIFAVLFVTGSANLVNMLAGFNGLEIGTSTIALL
FLALITDGNAQLLALTGLGAALGFLRWNKYPAKVFPGDTGTLSMGALIGLIGIIGKVEVYTAILLIPHFLDFIIKATSVR
FGVRRHGKTKVLPDGTLQAPPYPSFLGTIMRKIRVNEPKLVAIVWLVEATLGLLVLVLRQSL

Sequences:

>Translated_302_residues
MIVVAPLIGLTLTLIMTPYIAERMRRAGIVGRDIHKLDQPEVPEMGGIALILALPVALSPFLTEKISLATTVFLLFGIIG
VVDDLTNLRQLHKVILSLFVSIPVAVIGVSSHIDIFGFDLNLGVLYPIFAVLFVTGSANLVNMLAGFNGLEIGTSTIALL
FLALITDGNAQLLALTGLGAALGFLRWNKYPAKVFPGDTGTLSMGALIGLIGIIGKVEVYTAILLIPHFLDFIIKATSVR
FGVRRHGKTKVLPDGTLQAPPYPSFLGTIMRKIRVNEPKLVAIVWLVEATLGLLVLVLRQSL
>Mature_302_residues
MIVVAPLIGLTLTLIMTPYIAERMRRAGIVGRDIHKLDQPEVPEMGGIALILALPVALSPFLTEKISLATTVFLLFGIIG
VVDDLTNLRQLHKVILSLFVSIPVAVIGVSSHIDIFGFDLNLGVLYPIFAVLFVTGSANLVNMLAGFNGLEIGTSTIALL
FLALITDGNAQLLALTGLGAALGFLRWNKYPAKVFPGDTGTLSMGALIGLIGIIGKVEVYTAILLIPHFLDFIIKATSVR
FGVRRHGKTKVLPDGTLQAPPYPSFLGTIMRKIRVNEPKLVAIVWLVEATLGLLVLVLRQSL

Specific function: First Step Of The Lipid Cycle Reactions In The Biosynthesis Of The Cell Wall Peptidoglycan. [C]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Homo sapiens, GI42794009, Length=273, Percent_Identity=24.1758241758242, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319720, Length=207, Percent_Identity=31.4009661835749, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI19921214, Length=278, Percent_Identity=25.8992805755396, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.15 [H]

Molecular weight: Translated: 32436; Mature: 32436

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVAPLIGLTLTLIMTPYIAERMRRAGIVGRDIHKLDQPEVPEMGGIALILALPVALSP
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FLTEKISLATTVFLLFGIIGVVDDLTNLRQLHKVILSLFVSIPVAVIGVSSHIDIFGFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEC
NLGVLYPIFAVLFVTGSANLVNMLAGFNGLEIGTSTIALLFLALITDGNAQLLALTGLGA
CHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
ALGFLRWNKYPAKVFPGDTGTLSMGALIGLIGIIGKVEVYTAILLIPHFLDFIIKATSVR
HHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVRRHGKTKVLPDGTLQAPPYPSFLGTIMRKIRVNEPKLVAIVWLVEATLGLLVLVLRQ
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SL
CC
>Mature Secondary Structure
MIVVAPLIGLTLTLIMTPYIAERMRRAGIVGRDIHKLDQPEVPEMGGIALILALPVALSP
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FLTEKISLATTVFLLFGIIGVVDDLTNLRQLHKVILSLFVSIPVAVIGVSSHIDIFGFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEC
NLGVLYPIFAVLFVTGSANLVNMLAGFNGLEIGTSTIALLFLALITDGNAQLLALTGLGA
CHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
ALGFLRWNKYPAKVFPGDTGTLSMGALIGLIGIIGKVEVYTAILLIPHFLDFIIKATSVR
HHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVRRHGKTKVLPDGTLQAPPYPSFLGTIMRKIRVNEPKLVAIVWLVEATLGLLVLVLRQ
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8182085 [H]