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The map label for this gene is aotQ [H]

Identifier: 209695419

GI number: 209695419

Start: 2099799

End: 2100539

Strand: Direct

Name: aotQ [H]

Synonym: VSAL_I1959

Alternate gene names: 209695419

Gene position: 2099799-2100539 (Clockwise)

Preceding gene: 209695418

Following gene: 209695420

Centisome position: 63.15

GC content: 41.03

Gene sequence:

>741_bases
ATGTTAGATTTGCAAGGATATGAGTCCTCGATTTTAGATGGGGCATTAGTTACGTTACAAGTCGCACTGCTATCACTCAT
TTTAGCCGTGTTTTTAGGGATGTTAGGTGCGTTAGCTAAATTAGCGCCGTATCGCTGGGCTCGATCTATTGCGACAGTCT
ACACTACCGTTGTTCGTGGTATTCCTGATCTTGTCTTAATGATGTTGCTATTTTTTGGCGGACAGATGCTATTGAATAAT
GGCCTGTATGAGTCAAATGAATGGATCAACGAATGGATGACAAGTTCAGACCCAAATCATGAATGGGTTGCCTATCTTCC
TGATTATATAGAAATTAGTCCATTTATTGCTGGTGTTCTTACGATAGGTTTCATTTTTGGTGCTTATATGGCAGAGACGT
TTCGTGGGGCGATTATGGCTGTTGACCGAGGCGAAATGGAAGCAGCCAAAGCCTATGGTATGAGTGGTCCAATGGCCTTC
CGTCGTATTTTGTTTCCACAGATGATTAGGCATGCGTTACCGGGTTTTGGTAATAACTGGTTAGTGTTATTAAAAACGAC
CGCTTTAGTTTCAATCATTGGATTAGAAGACATGGTTCGTGTTAGTTCTATGGCAGCTGGTACAACCAAAATGCCGTTTA
CTTTTTATATGACCGTTGCTTGTATTTTCTTATTATTCACTGCCGTGTCGACTGGTGCTTTAAAACTGGTTGAGCGTAAA
TTTAGTATTCATACGAGGTAA

Upstream 100 bases:

>100_bases
ATGGTGAATAAGTACAAAAAGTACTAATTCATATGAAAGAGGCCGTAGTCTATAGCCTCTTTCAATTTTCTAATAGTTAA
AGCGAAAGCTTGGAAGCAGT

Downstream 100 bases:

>100_bases
GCATGGATTTTTCAATTATTATTGAGAGCCTACCCGTTTATTTGGATGGCCTTTGGACTACTGTTTGGTTAGTCGCTTTA
TCTCTTATTATTGGGTTGTG

Product: arginine/ornithine periplasmic binding protein-dependent transporter inner membrane component

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MLDLQGYESSILDGALVTLQVALLSLILAVFLGMLGALAKLAPYRWARSIATVYTTVVRGIPDLVLMMLLFFGGQMLLNN
GLYESNEWINEWMTSSDPNHEWVAYLPDYIEISPFIAGVLTIGFIFGAYMAETFRGAIMAVDRGEMEAAKAYGMSGPMAF
RRILFPQMIRHALPGFGNNWLVLLKTTALVSIIGLEDMVRVSSMAAGTTKMPFTFYMTVACIFLLFTAVSTGALKLVERK
FSIHTR

Sequences:

>Translated_246_residues
MLDLQGYESSILDGALVTLQVALLSLILAVFLGMLGALAKLAPYRWARSIATVYTTVVRGIPDLVLMMLLFFGGQMLLNN
GLYESNEWINEWMTSSDPNHEWVAYLPDYIEISPFIAGVLTIGFIFGAYMAETFRGAIMAVDRGEMEAAKAYGMSGPMAF
RRILFPQMIRHALPGFGNNWLVLLKTTALVSIIGLEDMVRVSSMAAGTTKMPFTFYMTVACIFLLFTAVSTGALKLVERK
FSIHTR
>Mature_246_residues
MLDLQGYESSILDGALVTLQVALLSLILAVFLGMLGALAKLAPYRWARSIATVYTTVVRGIPDLVLMMLLFFGGQMLLNN
GLYESNEWINEWMTSSDPNHEWVAYLPDYIEISPFIAGVLTIGFIFGAYMAETFRGAIMAVDRGEMEAAKAYGMSGPMAF
RRILFPQMIRHALPGFGNNWLVLLKTTALVSIIGLEDMVRVSSMAAGTTKMPFTFYMTVACIFLLFTAVSTGALKLVERK
FSIHTR

Specific function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=243, Percent_Identity=46.5020576131687, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI1787087, Length=235, Percent_Identity=34.468085106383, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787030, Length=233, Percent_Identity=27.8969957081545, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788226, Length=237, Percent_Identity=26.1603375527426, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788645, Length=233, Percent_Identity=25.7510729613734, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786874, Length=235, Percent_Identity=25.9574468085106, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786873, Length=198, Percent_Identity=25.2525252525253, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994930, Length=120, Percent_Identity=28.3333333333333, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27236; Mature: 27236

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLQGYESSILDGALVTLQVALLSLILAVFLGMLGALAKLAPYRWARSIATVYTTVVRG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPDLVLMMLLFFGGQMLLNNGLYESNEWINEWMTSSDPNHEWVAYLPDYIEISPFIAGVL
CHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCCCHHEECCCHHHHHHHHHHHH
TIGFIFGAYMAETFRGAIMAVDRGEMEAAKAYGMSGPMAFRRILFPQMIRHALPGFGNNW
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCE
LVLLKTTALVSIIGLEDMVRVSSMAAGTTKMPFTFYMTVACIFLLFTAVSTGALKLVERK
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSIHTR
HHCCCC
>Mature Secondary Structure
MLDLQGYESSILDGALVTLQVALLSLILAVFLGMLGALAKLAPYRWARSIATVYTTVVRG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPDLVLMMLLFFGGQMLLNNGLYESNEWINEWMTSSDPNHEWVAYLPDYIEISPFIAGVL
CHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCCCHHEECCCHHHHHHHHHHHH
TIGFIFGAYMAETFRGAIMAVDRGEMEAAKAYGMSGPMAFRRILFPQMIRHALPGFGNNW
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCE
LVLLKTTALVSIIGLEDMVRVSSMAAGTTKMPFTFYMTVACIFLLFTAVSTGALKLVERK
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSIHTR
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]