Click here to switch to the map view.

The map label for this gene is prc [H]

Identifier: 209695049

GI number: 209695049

Start: 1647271

End: 1649289

Strand: Direct

Name: prc [H]

Synonym: VSAL_I1544

Alternate gene names: 209695049

Gene position: 1647271-1649289 (Clockwise)

Preceding gene: 209695048

Following gene: 209695050

Centisome position: 49.54

GC content: 37.94

Gene sequence:

>2019_bases
ATGAATTGTCGATTTAGAGTCTCGCTGATTGCTGCTGGCGTAATGCTAGCAGCGTCTGCACACGCACTTGAAGCTAAGGT
TCTTGAAGCCAAGTATTCAGAAACGGACTTACCTGTATTAGCGGCTGAAACTCAGCACGCGACAGCAAGTAAGCGCGTTA
CTTCTCGTTTTACACGTTCTCATTATAAGCATTTCTCATTGAATGATGACTTCTCAGTTGCCATTTATGAGCGATATTTA
GACATGCTCGATTATAATCGAAACGTGTTTATTCAAGCGGATCTTACCTCTTTCGCTCCATTATCAACCAAATTTGATGA
TCAATTAAAAGTGGGTGATACTCAAGCCGCCTTTGATATTTATAACTTATCACTCAAACGTCGTTTTGAGCGTTACGTTT
ATGCATTGTCTTTATTAGATAAAGAGTTTGATTATACTGTTGATGAATCTTTTGAGTTAGATCGCTCTGACGCGGCATGG
CCAAAAGATGACGCTGAGTTAAATGAACTTTGGCGTAAACGTGTTAAATATGATGCGCTTAACTTGTCTATGACAGGAAA
AGATTGGCCTGAAATCCAAAAGATGTTGGGCAAGCGTTATAATAATGCGTTAAAGCGTTTGACTCAAAGTCACAACGAAG
ATGCGTTCCAACTTTACATTAATGCATTTGCTCGTGAAGTTGATCCTCATACTAGCTATTTATCCCCACGAAATGCTGAA
CAATTCCAATCTGAAATGAATCTTTCATTAGAAGGTATTGGTGCGGTATTGCAAGCGACCGATGACTATACTGTTATTCG
ATCTCTCGTGGCTGGTGGTCCTGCACAAAACAGTAAACAACTTTCAGAAGGTGACCGAATTATTGGTGTTGCTCAAGAAG
GTGAAAAATCTGTTGATGTGATTGGTTGGCGTTTAGATGACGTTGTTCAATTAATAAAAGGCCCTAAAGGAACAAAAGTG
TATCTTGATATCTTGCCAGAAGGTAAAGATTCAAAAAGTCACGTTGTCACAATTGTTCGAGATAAGATTCGTTTAGAAGA
AGATAGAGCAGTTAAGTCTGAAGTGATTGAGCAAGACGGCAAGAAAATTGGTGTATTAGAAGTACCAAGTTTCTATGTTG
GCTTAGCTGAAGACACTAAAAAACAAATTGCTGAATTAAAAGAAAAAAACATTACCGGTATTGTTGTCGATTTACGTAAC
AATGGTGGTGGTGCATTAACTGAAGCAACGGCATTATCTGGTTTATTTATTACATCAGGTCCTGTAGTTCAAGTTCGTGA
TAGTTATGGACGTGTTAATGTCAATGCTGATACTGATGGTGAAATTGCTTATACTGGTCCGATGACTGTATTAGTGAATC
GTTATAGTGCCTCAGCTTCTGAAATTTTTGCTGCAGCAATGCAAGATTATGGCCGTGCTGTAATTTTAGGCGAAAATTCA
TTTGGTAAAGGAACAGTACAACAGCATCGTTCATTGAATCATATTTATGATTTATTTGATAAGCCACTAGGTCATGTTCA
ATACACAATTCAAAAATTCTATCGAATCAATGGTGGTAGTACGCAAAATTTAGGTGTTGTTCCTGATATTGCATTTCCAA
CCGCGATTGATGCTAAAGATACTGGCGAAAGTGTTGAAGATAATGCACTTCCTTGGGATAGCATTAAAGCAGCCGAGTAT
AAGCAAACAAATCAGATTGCGAACACGATTGCTCCATTGGCACAAAAGCATGTCGAACGAATCAAATCAGATGAAGAGTT
TGGTTTCATTCAAGAAGATATTGCTCGCTATAAAGCTGAAAAAGACATTACTTCGATGTCACTAAACAAGAAAGTGCGTG
AGAAAGAAAGTGATGATGCTGATGTTCGTCGTTTAGATCGTGTAAATCAAAGACAAAAACATCTTGAAAAAGAAGCGTTT
AAATCTATTGATGACATACCAAAAGATTATGAAGCACCAGATGCTTATTTAGACGAAGCAGTGTCAATTACCATTGATTT
GGCAACAATGGAACGTTAA

Upstream 100 bases:

>100_bases
TAGAAATTAACAAGGATGATGTTCGAATTCGCTTATCAAACGGCCTACAAATGGTTGTTAAAGCGGAGAACCTTCGTTCA
TAAAGGAGTACTCCCGACGC

Downstream 100 bases:

>100_bases
TACTTAAGAAGATTGTTATTCTTGATGTGAACGTTTTCATTATCGTTATTTAAAAACAGAAGCTATTTATGGCTTCTGTT
TTTTTATACGTAAAATTCAA

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MNCRFRVSLIAAGVMLAASAHALEAKVLEAKYSETDLPVLAAETQHATASKRVTSRFTRSHYKHFSLNDDFSVAIYERYL
DMLDYNRNVFIQADLTSFAPLSTKFDDQLKVGDTQAAFDIYNLSLKRRFERYVYALSLLDKEFDYTVDESFELDRSDAAW
PKDDAELNELWRKRVKYDALNLSMTGKDWPEIQKMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPAQNSKQLSEGDRIIGVAQEGEKSVDVIGWRLDDVVQLIKGPKGTKV
YLDILPEGKDSKSHVVTIVRDKIRLEEDRAVKSEVIEQDGKKIGVLEVPSFYVGLAEDTKKQIAELKEKNITGIVVDLRN
NGGGALTEATALSGLFITSGPVVQVRDSYGRVNVNADTDGEIAYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENS
FGKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDAKDTGESVEDNALPWDSIKAAEY
KQTNQIANTIAPLAQKHVERIKSDEEFGFIQEDIARYKAEKDITSMSLNKKVREKESDDADVRRLDRVNQRQKHLEKEAF
KSIDDIPKDYEAPDAYLDEAVSITIDLATMER

Sequences:

>Translated_672_residues
MNCRFRVSLIAAGVMLAASAHALEAKVLEAKYSETDLPVLAAETQHATASKRVTSRFTRSHYKHFSLNDDFSVAIYERYL
DMLDYNRNVFIQADLTSFAPLSTKFDDQLKVGDTQAAFDIYNLSLKRRFERYVYALSLLDKEFDYTVDESFELDRSDAAW
PKDDAELNELWRKRVKYDALNLSMTGKDWPEIQKMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPAQNSKQLSEGDRIIGVAQEGEKSVDVIGWRLDDVVQLIKGPKGTKV
YLDILPEGKDSKSHVVTIVRDKIRLEEDRAVKSEVIEQDGKKIGVLEVPSFYVGLAEDTKKQIAELKEKNITGIVVDLRN
NGGGALTEATALSGLFITSGPVVQVRDSYGRVNVNADTDGEIAYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENS
FGKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDAKDTGESVEDNALPWDSIKAAEY
KQTNQIANTIAPLAQKHVERIKSDEEFGFIQEDIARYKAEKDITSMSLNKKVREKESDDADVRRLDRVNQRQKHLEKEAF
KSIDDIPKDYEAPDAYLDEAVSITIDLATMER
>Mature_672_residues
MNCRFRVSLIAAGVMLAASAHALEAKVLEAKYSETDLPVLAAETQHATASKRVTSRFTRSHYKHFSLNDDFSVAIYERYL
DMLDYNRNVFIQADLTSFAPLSTKFDDQLKVGDTQAAFDIYNLSLKRRFERYVYALSLLDKEFDYTVDESFELDRSDAAW
PKDDAELNELWRKRVKYDALNLSMTGKDWPEIQKMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPAQNSKQLSEGDRIIGVAQEGEKSVDVIGWRLDDVVQLIKGPKGTKV
YLDILPEGKDSKSHVVTIVRDKIRLEEDRAVKSEVIEQDGKKIGVLEVPSFYVGLAEDTKKQIAELKEKNITGIVVDLRN
NGGGALTEATALSGLFITSGPVVQVRDSYGRVNVNADTDGEIAYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENS
FGKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDAKDTGESVEDNALPWDSIKAAEY
KQTNQIANTIAPLAQKHVERIKSDEEFGFIQEDIARYKAEKDITSMSLNKKVREKESDDADVRRLDRVNQRQKHLEKEAF
KSIDDIPKDYEAPDAYLDEAVSITIDLATMER

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=678, Percent_Identity=55.8997050147493, Blast_Score=771, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 75429; Mature: 75429

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCRFRVSLIAAGVMLAASAHALEAKVLEAKYSETDLPVLAAETQHATASKRVTSRFTRS
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHH
HYKHFSLNDDFSVAIYERYLDMLDYNRNVFIQADLTSFAPLSTKFDDQLKVGDTQAAFDI
HCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEECCCCHHHHHH
YNLSLKRRFERYVYALSLLDKEFDYTVDESFELDRSDAAWPKDDAELNELWRKRVKYDAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCEE
NLSMTGKDWPEIQKMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPAQNSKQLSEGDRIIGVAQEGEKSVDV
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHCCCCEEEEECCCCCCCEEE
IGWRLDDVVQLIKGPKGTKVYLDILPEGKDSKSHVVTIVRDKIRLEEDRAVKSEVIEQDG
EEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCC
KKIGVLEVPSFYVGLAEDTKKQIAELKEKNITGIVVDLRNNGGGALTEATALSGLFITSG
CEEEEEECCHHEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCEEEECCC
PVVQVRDSYGRVNVNADTDGEIAYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENS
CEEEEECCCCEEEECCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCC
FGKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDAKD
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCC
TGESVEDNALPWDSIKAAEYKQTNQIANTIAPLAQKHVERIKSDEEFGFIQEDIARYKAE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KDITSMSLNKKVREKESDDADVRRLDRVNQRQKHLEKEAFKSIDDIPKDYEAPDAYLDEA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCC
VSITIDLATMER
EEEEEEEEECCC
>Mature Secondary Structure
MNCRFRVSLIAAGVMLAASAHALEAKVLEAKYSETDLPVLAAETQHATASKRVTSRFTRS
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHH
HYKHFSLNDDFSVAIYERYLDMLDYNRNVFIQADLTSFAPLSTKFDDQLKVGDTQAAFDI
HCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEECCCCHHHHHH
YNLSLKRRFERYVYALSLLDKEFDYTVDESFELDRSDAAWPKDDAELNELWRKRVKYDAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCEE
NLSMTGKDWPEIQKMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPAQNSKQLSEGDRIIGVAQEGEKSVDV
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHCCCCEEEEECCCCCCCEEE
IGWRLDDVVQLIKGPKGTKVYLDILPEGKDSKSHVVTIVRDKIRLEEDRAVKSEVIEQDG
EEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCC
KKIGVLEVPSFYVGLAEDTKKQIAELKEKNITGIVVDLRNNGGGALTEATALSGLFITSG
CEEEEEECCHHEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCEEEECCC
PVVQVRDSYGRVNVNADTDGEIAYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENS
CEEEEECCCCEEEECCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCC
FGKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDAKD
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCC
TGESVEDNALPWDSIKAAEYKQTNQIANTIAPLAQKHVERIKSDEEFGFIQEDIARYKAE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KDITSMSLNKKVREKESDDADVRRLDRVNQRQKHLEKEAFKSIDDIPKDYEAPDAYLDEA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCC
VSITIDLATMER
EEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]