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The map label for this gene is ligA [H]

Identifier: 209694893

GI number: 209694893

Start: 1487015

End: 1487869

Strand: Direct

Name: ligA [H]

Synonym: VSAL_I1366

Alternate gene names: 209694893

Gene position: 1487015-1487869 (Clockwise)

Preceding gene: 209694888

Following gene: 209694900

Centisome position: 44.72

GC content: 40.94

Gene sequence:

>855_bases
ATGAAAGTATCAACATTATCGACACTCATTGGCATCGGATTGTTCTCTGCTCCCATGCTTGCTTTTGATAAATCTAATAC
AGTCCCTGTTTCTGTATTGTTGGCAACAAGCTATGAAGAAGGGATAGAGGTTGATAAATATTGGGTCAGTGAAAAGCTCG
ATGGAATAAGAGCGTATTGGACGGGGTCAGAGTTACTTACTCGTAAAGGTCATAAAATCATGGCACCCGATTGGTTTATT
GCGCCGCTTCCTAAGCACGCGATTGATGGTGAATTATGGGCCGGACGTGGTGGTTTTCAGCAAGTAGCGAGTACCGTATT
AGATAGCCAACCTGATGATGAGTTATGGGCCGAAATTACGTTCATGATGTTTGATATTCCTCATTCTATTGGTATGTTTC
CTCAGCGTTATTCTGACTTATCATTATTGGTGCAAGGCCTAGCAACTCCCCACCTTAAATTAGTAGAACACCACCCAATT
AGCAGTGAAGATGATTTACTCAAATCCCTTGAAGAGATGGCAGTGAATAAAGGCGAAGGCTTAATGCTAAGAAAACTCGA
TTCTATTTATCGAGCGGGCAGAAGTGATGATCTGATCAAGTTAAAAAAACACTATGATGATGAAGCGATTATTGTGGGTT
ATACCGATGGAAAAGGTAAATTTGAAGGGATGGTCGGGGCGTTAATATTGCAAATGCCAAATGGACAAGAGTTTAAGATT
GGCAGTGGATTAAGCAATGAAGTGCGAGAAAACCCACCAATATTAGGGCAGCAAGTGACTTATCGTTATAATGGCTTTAC
GGACAGTGGTATTCCTAAGTTTGCGCGATATATTGCGGTTCGTGAAAAATATTAA

Upstream 100 bases:

>100_bases
TCGAAATTGCGTAATAGAAGTGACTGAATTAGGGATAAATCGTTGTTCAACATGCAATGATAGAAAACATCAATATTAAA
AACCATTAAGCTAGGTATCT

Downstream 100 bases:

>100_bases
TAGAGTTTCTACATGGATAGAAACTCTATTTTTTAATGTAGCTAGCGGCTTGATATTAAATCGTTTTAACACTGTCACGA
ATCATTAATGTCGGTTCCAG

Product: DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKVSTLSTLIGIGLFSAPMLAFDKSNTVPVSVLLATSYEEGIEVDKYWVSEKLDGIRAYWTGSELLTRKGHKIMAPDWFI
APLPKHAIDGELWAGRGGFQQVASTVLDSQPDDELWAEITFMMFDIPHSIGMFPQRYSDLSLLVQGLATPHLKLVEHHPI
SSEDDLLKSLEEMAVNKGEGLMLRKLDSIYRAGRSDDLIKLKKHYDDEAIIVGYTDGKGKFEGMVGALILQMPNGQEFKI
GSGLSNEVRENPPILGQQVTYRYNGFTDSGIPKFARYIAVREKY

Sequences:

>Translated_284_residues
MKVSTLSTLIGIGLFSAPMLAFDKSNTVPVSVLLATSYEEGIEVDKYWVSEKLDGIRAYWTGSELLTRKGHKIMAPDWFI
APLPKHAIDGELWAGRGGFQQVASTVLDSQPDDELWAEITFMMFDIPHSIGMFPQRYSDLSLLVQGLATPHLKLVEHHPI
SSEDDLLKSLEEMAVNKGEGLMLRKLDSIYRAGRSDDLIKLKKHYDDEAIIVGYTDGKGKFEGMVGALILQMPNGQEFKI
GSGLSNEVRENPPILGQQVTYRYNGFTDSGIPKFARYIAVREKY
>Mature_284_residues
MKVSTLSTLIGIGLFSAPMLAFDKSNTVPVSVLLATSYEEGIEVDKYWVSEKLDGIRAYWTGSELLTRKGHKIMAPDWFI
APLPKHAIDGELWAGRGGFQQVASTVLDSQPDDELWAEITFMMFDIPHSIGMFPQRYSDLSLLVQGLATPHLKLVEHHPI
SSEDDLLKSLEEMAVNKGEGLMLRKLDSIYRAGRSDDLIKLKKHYDDEAIIVGYTDGKGKFEGMVGALILQMPNGQEFKI
GSGLSNEVRENPPILGQQVTYRYNGFTDSGIPKFARYIAVREKY

Specific function: Catalyzes efficient strand joining on a single nicked DNA [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 31717; Mature: 31717

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSTLSTLIGIGLFSAPMLAFDKSNTVPVSVLLATSYEEGIEVDKYWVSEKLDGIRAYW
CCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECCHHCCCHHHHHHHHHHCCEEEEE
TGSELLTRKGHKIMAPDWFIAPLPKHAIDGELWAGRGGFQQVASTVLDSQPDDELWAEIT
CCHHHHHHCCCEEECCCEEECCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHH
FMMFDIPHSIGMFPQRYSDLSLLVQGLATPHLKLVEHHPISSEDDLLKSLEEMAVNKGEG
HHEEECCHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
LMLRKLDSIYRAGRSDDLIKLKKHYDDEAIIVGYTDGKGKFEGMVGALILQMPNGQEFKI
HHHHHHHHHHHCCCCCCEEEHHHCCCCCEEEEEEECCCCHHHHEEEEEEEECCCCCEEEE
GSGLSNEVRENPPILGQQVTYRYNGFTDSGIPKFARYIAVREKY
CCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVSTLSTLIGIGLFSAPMLAFDKSNTVPVSVLLATSYEEGIEVDKYWVSEKLDGIRAYW
CCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECCHHCCCHHHHHHHHHHCCEEEEE
TGSELLTRKGHKIMAPDWFIAPLPKHAIDGELWAGRGGFQQVASTVLDSQPDDELWAEIT
CCHHHHHHCCCEEECCCEEECCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHH
FMMFDIPHSIGMFPQRYSDLSLLVQGLATPHLKLVEHHPISSEDDLLKSLEEMAVNKGEG
HHEEECCHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
LMLRKLDSIYRAGRSDDLIKLKKHYDDEAIIVGYTDGKGKFEGMVGALILQMPNGQEFKI
HHHHHHHHHHHCCCCCCEEEHHHCCCCCEEEEEEECCCCHHHHEEEEEEEECCCCCEEEE
GSGLSNEVRENPPILGQQVTYRYNGFTDSGIPKFARYIAVREKY
CCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550458; 7542800; 9060431 [H]