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The map label for this gene is gltA [H]

Identifier: 209694420

GI number: 209694420

Start: 935590

End: 936879

Strand: Reverse

Name: gltA [H]

Synonym: VSAL_I0841

Alternate gene names: 209694420

Gene position: 936879-935590 (Counterclockwise)

Preceding gene: 209694429

Following gene: 209694416

Centisome position: 28.18

GC content: 40.93

Gene sequence:

>1290_bases
ATGGCTGATAAGAAAGCAACTCTTCACATTGAAGGTCAAGCACCAATAGACATGCCAGTAATGGAAGGCACTATCGGACC
TGAAGTGATTGATGTACGCAAATTAGGCGCTAATGGTTACTTCACTTTTGACCCTGGTTTTCTTGCCACTGCATCTTGTG
AATCTCAAATTACCTACATTGATGGTGACAAAGGTGTATTACTACACCGTGGCTTCCCAATCGATCAGTTAGCAAATAAT
GCTGATTACTTAGAAGTATGTTACATACTACTGAATGGCCAAGCACCAAGCCGTGAAGAATACGAAACGTTCAAAGATAT
TGTTACCCGTCATACGATGGTTCACGAACAAATTTCAAGCTTCTTCCATGGGTTCCGTCGTGATGCTCACCCAATGGCTG
TAATGTGTGGTGTAGTTGGTGCATTAGCGGCCTTCTACCATGATTCACTAGATATTAATAATGATGAACATCGTGAAATT
GCGGCATTTAGACTTCTATCTAAAATGCCAACACTTTCAGCGATGTGCTACAAATATTCGATTGGTCAACCGTTTATCTA
TCCACGTAACGACTTAACGTATGCTGAAAACTTCTTGCACATGATGTTCGCAAACCCATGTGAAGAATATGAAGTAAATC
CTGTTGTTGCTCGTGCTATGGATAAAATATTTACTCTGCATGCTGATCATGAACAAAATGCGTCAACATCAACAGTTCGT
TTAGCGGGCTCTTCAGGTGCAAACCCATTTGCATGTATCGCCGCAGGTATTGCTTCTCTTTGGGGACCAGCACATGGTGG
TGCAAATGAAGCTTGTTTGCGTATGCTTGAAGAAATTGGCTCTCTTGATAATATTGATGAGTACGTTGCAAAAGCAAAAG
ATAAGGAAGACCCTTTCCGATTAATGGGCTTTGGACACCGTGTTTATAAAAACTACGATCCACGAGCAACAGTAATGCGT
GAAGCGTGTCATGAAGTATTGAAAGAGCTAAACATTAAAGATCCACTGTTAGATGTAGCAATGGAACTTGAACGAATTGC
GCTATCTGATGAATACTTTGTATCTAAAAAACTGTATCCAAACGTAGATTTCTACTCAGGTATTATTCTAAAAGCGATTG
GGATCCCTGCATCAATGTTTACTGTTATTTTTGCACTGTCTCGTACTGTTGGTTGGATCGCACACTGGAGCGAAATGCAC
AGTGATCCAGATAACCGTATTGGTCGTCCTCGCCAACTTTATACAGGTGAAGAGTTACGCGAATTTAAACCACTTCACGA
ACGTGAATAA

Upstream 100 bases:

>100_bases
CACATAAGCGCACAAAAATTGACATTAGCCCGTGTAATGGGTACAAAGTTGTCACTCTCATATCCGGGATAGAATAAAAA
TATAACAAAAGGAGAATGTT

Downstream 100 bases:

>100_bases
TTTAGAGTTCATGTAGGTAATCACTATCTCTTAAATAAAAAGGTTGATGCGTTAGCATCAACCTTTTTTATTCTGATTTA
ATTTAAATAACATCAAATAA

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MADKKATLHIEGQAPIDMPVMEGTIGPEVIDVRKLGANGYFTFDPGFLATASCESQITYIDGDKGVLLHRGFPIDQLANN
ADYLEVCYILLNGQAPSREEYETFKDIVTRHTMVHEQISSFFHGFRRDAHPMAVMCGVVGALAAFYHDSLDINNDEHREI
AAFRLLSKMPTLSAMCYKYSIGQPFIYPRNDLTYAENFLHMMFANPCEEYEVNPVVARAMDKIFTLHADHEQNASTSTVR
LAGSSGANPFACIAAGIASLWGPAHGGANEACLRMLEEIGSLDNIDEYVAKAKDKEDPFRLMGFGHRVYKNYDPRATVMR
EACHEVLKELNIKDPLLDVAMELERIALSDEYFVSKKLYPNVDFYSGIILKAIGIPASMFTVIFALSRTVGWIAHWSEMH
SDPDNRIGRPRQLYTGEELREFKPLHERE

Sequences:

>Translated_429_residues
MADKKATLHIEGQAPIDMPVMEGTIGPEVIDVRKLGANGYFTFDPGFLATASCESQITYIDGDKGVLLHRGFPIDQLANN
ADYLEVCYILLNGQAPSREEYETFKDIVTRHTMVHEQISSFFHGFRRDAHPMAVMCGVVGALAAFYHDSLDINNDEHREI
AAFRLLSKMPTLSAMCYKYSIGQPFIYPRNDLTYAENFLHMMFANPCEEYEVNPVVARAMDKIFTLHADHEQNASTSTVR
LAGSSGANPFACIAAGIASLWGPAHGGANEACLRMLEEIGSLDNIDEYVAKAKDKEDPFRLMGFGHRVYKNYDPRATVMR
EACHEVLKELNIKDPLLDVAMELERIALSDEYFVSKKLYPNVDFYSGIILKAIGIPASMFTVIFALSRTVGWIAHWSEMH
SDPDNRIGRPRQLYTGEELREFKPLHERE
>Mature_428_residues
ADKKATLHIEGQAPIDMPVMEGTIGPEVIDVRKLGANGYFTFDPGFLATASCESQITYIDGDKGVLLHRGFPIDQLANNA
DYLEVCYILLNGQAPSREEYETFKDIVTRHTMVHEQISSFFHGFRRDAHPMAVMCGVVGALAAFYHDSLDINNDEHREIA
AFRLLSKMPTLSAMCYKYSIGQPFIYPRNDLTYAENFLHMMFANPCEEYEVNPVVARAMDKIFTLHADHEQNASTSTVRL
AGSSGANPFACIAAGIASLWGPAHGGANEACLRMLEEIGSLDNIDEYVAKAKDKEDPFRLMGFGHRVYKNYDPRATVMRE
ACHEVLKELNIKDPLLDVAMELERIALSDEYFVSKKLYPNVDFYSGIILKAIGIPASMFTVIFALSRTVGWIAHWSEMHS
DPDNRIGRPRQLYTGEELREFKPLHERE

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=398, Percent_Identity=26.8844221105528, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1786939, Length=423, Percent_Identity=75.886524822695, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1786527, Length=377, Percent_Identity=31.0344827586207, Blast_Score=162, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=345, Percent_Identity=27.2463768115942, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319850, Length=365, Percent_Identity=26.5753424657534, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324328, Length=326, Percent_Identity=26.9938650306748, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325257, Length=364, Percent_Identity=26.6483516483516, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24640126, Length=352, Percent_Identity=26.4204545454545, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24640124, Length=352, Percent_Identity=26.4204545454545, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356863, Length=402, Percent_Identity=25.3731343283582, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48249; Mature: 48117

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKATLHIEGQAPIDMPVMEGTIGPEVIDVRKLGANGYFTFDPGFLATASCESQITYI
CCCCCEEEEECCCCCCCCCHHCCCCCCCHHHHEEECCCCEEEECCCCEEECCCCCEEEEE
DGDKGVLLHRGFPIDQLANNADYLEVCYILLNGQAPSREEYETFKDIVTRHTMVHEQISS
ECCCCEEEECCCCHHHHCCCCCHHHHEEHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFHGFRRDAHPMAVMCGVVGALAAFYHDSLDINNDEHREIAAFRLLSKMPTLSAMCYKYS
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHC
IGQPFIYPRNDLTYAENFLHMMFANPCEEYEVNPVVARAMDKIFTLHADHEQNASTSTVR
CCCCCEECCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIASLWGPAHGGANEACLRMLEEIGSLDNIDEYVAKAKDKEDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHH
LMGFGHRVYKNYDPRATVMREACHEVLKELNIKDPLLDVAMELERIALSDEYFVSKKLYP
HHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCC
NVDFYSGIILKAIGIPASMFTVIFALSRTVGWIAHWSEMHSDPDNRIGRPRQLYTGEELR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHH
EFKPLHERE
HCCCCCCCC
>Mature Secondary Structure 
ADKKATLHIEGQAPIDMPVMEGTIGPEVIDVRKLGANGYFTFDPGFLATASCESQITYI
CCCCEEEEECCCCCCCCCHHCCCCCCCHHHHEEECCCCEEEECCCCEEECCCCCEEEEE
DGDKGVLLHRGFPIDQLANNADYLEVCYILLNGQAPSREEYETFKDIVTRHTMVHEQISS
ECCCCEEEECCCCHHHHCCCCCHHHHEEHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFHGFRRDAHPMAVMCGVVGALAAFYHDSLDINNDEHREIAAFRLLSKMPTLSAMCYKYS
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHC
IGQPFIYPRNDLTYAENFLHMMFANPCEEYEVNPVVARAMDKIFTLHADHEQNASTSTVR
CCCCCEECCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIASLWGPAHGGANEACLRMLEEIGSLDNIDEYVAKAKDKEDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHH
LMGFGHRVYKNYDPRATVMREACHEVLKELNIKDPLLDVAMELERIALSDEYFVSKKLYP
HHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCC
NVDFYSGIILKAIGIPASMFTVIFALSRTVGWIAHWSEMHSDPDNRIGRPRQLYTGEELR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHH
EFKPLHERE
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]