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The map label for this gene is yhdH [H]

Identifier: 209694350

GI number: 209694350

Start: 851281

End: 852645

Strand: Direct

Name: yhdH [H]

Synonym: VSAL_I0762

Alternate gene names: 209694350

Gene position: 851281-852645 (Clockwise)

Preceding gene: 209694346

Following gene: 209694357

Centisome position: 25.6

GC content: 40.0

Gene sequence:

>1365_bases
ATGACAACAGGTAACAGAGAAAGTTTTAGTTCACGATTAGGGTTTATATTATCAGCTGCTGGTGCAGCGGTGGGTCTGGG
TAATATTTGGGGCTTCCCAACTCAGGCAGCAAGTAATGGTGGTGGTGCCTTTCTATTGGTTTATCTCATCATGATCCTTG
TGGTGGCTTTCCCTATGCTTGTTGTCGAAATGGCGATCGGTCGTCATGGTCAAGCAAACCCAGTAGACAGTATGCGAGCT
CTGACTTCAAATCCAATGGGTAAGCGTTTTGGTGCTTTTGTTGGGTGGATTGGTCTGAGTGTACCTAGTGTTGTACTGAT
GTTTTATAGCATTGTTGGTGGTTGGTTAATCTGTTTTCTATTTGGTGCGATGGCCAATGTTGTTGGATTGCATGATCTCG
CTGAGTGGTTTAAAGGTTTTAGCATTGAACGTAATTTACTGGGTACGATACTCTTTTATGTATTAACTATTTTAATCGTA
CAAGGTGGAATTAAAGACGGTATTGAAAAATGGTCTACTCGTTTGATGCCGGCATTATTTGTTTTATTTGGATTATTGTT
TGTTTATATCATGATGCAGCAGGGTGCTGTTGAAGGGCTAAAGCACTATCTGATTCCTGATTTTGAAAAAGTAATGGATA
AAAAATTGATTCTAGCAGCCATGGGGCAAGGCTTTTTCTCGCTAACCATTGGTGGCTGTTCAATGCTGATTTACGGATCG
TATTTAAGTAAGACAGAGAATTTACCTAAAATGGCGATGAACGTTACTTTAGTGGATACCGCTGTGGCATTTGTTGCGGG
CTTAGTGGTTATGCCTGCAATGTTTGTTGCAATGCAAAAGGGCGTTCAAATTTATGCCGAAGATGGATCGTTATTAAGTT
CTGACACGTTGGTGTTTACGGTTTTACCAATGATGTTTGATAGCTTAGGTTTATTGGGCGATCTGTTCGCCATTGCTTTC
TTCTTATTATTAACCATCGCTGCATTAACGTCTTCAATCTCAATGCTTGAATGTTCAGTTTCTTTAGTGAGTGAGCGATT
TGAAACGAGAAGAACACCAACAAGCTGGGTATTAGGTTTATTAATTGCCGTGTTTAGTGTGGTGATTGTCTTTAATTTTT
CTGAACTATTTGGCTTAGTTGCGATGATTGCAACGCAATATTTACAACCTGTCGCAGCATTATTGTTCTGTGTATTTGGT
GGCTGGGTGTGGAGTCGTCACTCTAAAATTAAAGAGCTTGAGCAAGGTTATCCTGAATTCCAACAAGGATTCTTTGGTAA
AGTTTGGCCTCTGTATGTGAAATTTGTGTGTCCTGTTTTAGTTATCGCCGTATTGTGGGCATCGTTCTTATTCGCTTATA
AATAA

Upstream 100 bases:

>100_bases
TTGTTAAGAGAAATAAATGAATGAAGCGAGTATTTAAATCTGGTGTTTAATTACGAGTGAAGTTATCATTCGCTTATTGT
ACTAGTGTGGTGATACAGAG

Downstream 100 bases:

>100_bases
ACAGCATTAAGATAGAAAAAAGCCAGCAGATAAATGCTGGCTGTTTTATTTTTTAACTATCGAAAAATACGATACATTCA
GTGGTTAATGCTTATTTTTT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTTGNRESFSSRLGFILSAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPMLVVEMAIGRHGQANPVDSMRA
LTSNPMGKRFGAFVGWIGLSVPSVVLMFYSIVGGWLICFLFGAMANVVGLHDLAEWFKGFSIERNLLGTILFYVLTILIV
QGGIKDGIEKWSTRLMPALFVLFGLLFVYIMMQQGAVEGLKHYLIPDFEKVMDKKLILAAMGQGFFSLTIGGCSMLIYGS
YLSKTENLPKMAMNVTLVDTAVAFVAGLVVMPAMFVAMQKGVQIYAEDGSLLSSDTLVFTVLPMMFDSLGLLGDLFAIAF
FLLLTIAALTSSISMLECSVSLVSERFETRRTPTSWVLGLLIAVFSVVIVFNFSELFGLVAMIATQYLQPVAALLFCVFG
GWVWSRHSKIKELEQGYPEFQQGFFGKVWPLYVKFVCPVLVIAVLWASFLFAYK

Sequences:

>Translated_454_residues
MTTGNRESFSSRLGFILSAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPMLVVEMAIGRHGQANPVDSMRA
LTSNPMGKRFGAFVGWIGLSVPSVVLMFYSIVGGWLICFLFGAMANVVGLHDLAEWFKGFSIERNLLGTILFYVLTILIV
QGGIKDGIEKWSTRLMPALFVLFGLLFVYIMMQQGAVEGLKHYLIPDFEKVMDKKLILAAMGQGFFSLTIGGCSMLIYGS
YLSKTENLPKMAMNVTLVDTAVAFVAGLVVMPAMFVAMQKGVQIYAEDGSLLSSDTLVFTVLPMMFDSLGLLGDLFAIAF
FLLLTIAALTSSISMLECSVSLVSERFETRRTPTSWVLGLLIAVFSVVIVFNFSELFGLVAMIATQYLQPVAALLFCVFG
GWVWSRHSKIKELEQGYPEFQQGFFGKVWPLYVKFVCPVLVIAVLWASFLFAYK
>Mature_453_residues
TTGNRESFSSRLGFILSAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPMLVVEMAIGRHGQANPVDSMRAL
TSNPMGKRFGAFVGWIGLSVPSVVLMFYSIVGGWLICFLFGAMANVVGLHDLAEWFKGFSIERNLLGTILFYVLTILIVQ
GGIKDGIEKWSTRLMPALFVLFGLLFVYIMMQQGAVEGLKHYLIPDFEKVMDKKLILAAMGQGFFSLTIGGCSMLIYGSY
LSKTENLPKMAMNVTLVDTAVAFVAGLVVMPAMFVAMQKGVQIYAEDGSLLSSDTLVFTVLPMMFDSLGLLGDLFAIAFF
LLLTIAALTSSISMLECSVSLVSERFETRRTPTSWVLGLLIAVFSVVIVFNFSELFGLVAMIATQYLQPVAALLFCVFGG
WVWSRHSKIKELEQGYPEFQQGFFGKVWPLYVKFVCPVLVIAVLWASFLFAYK

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=428, Percent_Identity=25.4672897196262, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI171184408, Length=413, Percent_Identity=25.6658595641646, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI171184406, Length=413, Percent_Identity=25.6658595641646, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI171184404, Length=413, Percent_Identity=25.6658595641646, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI134304856, Length=449, Percent_Identity=24.2761692650334, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI21361581, Length=508, Percent_Identity=24.4094488188976, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI4507041, Length=449, Percent_Identity=24.4988864142539, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI289191351, Length=413, Percent_Identity=25.181598062954, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI4557046, Length=413, Percent_Identity=25.181598062954, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI289191377, Length=413, Percent_Identity=24.9394673123487, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI188528618, Length=389, Percent_Identity=23.9074550128535, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI58219014, Length=304, Percent_Identity=24.3421052631579, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI197276623, Length=339, Percent_Identity=25.3687315634218, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI54607094, Length=339, Percent_Identity=25.3687315634218, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI7657587, Length=466, Percent_Identity=25.3218884120172, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI5032097, Length=337, Percent_Identity=27.0029673590504, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI11181770, Length=301, Percent_Identity=24.9169435215947, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI12408638, Length=269, Percent_Identity=26.7657992565056, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI33354281, Length=302, Percent_Identity=21.8543046357616, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI194018524, Length=300, Percent_Identity=23.6666666666667, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI67782317, Length=340, Percent_Identity=22.6470588235294, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI67782313, Length=340, Percent_Identity=22.6470588235294, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI67782315, Length=340, Percent_Identity=22.9411764705882, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI218563756, Length=337, Percent_Identity=26.1127596439169, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI92859670, Length=78, Percent_Identity=44.8717948717949, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI51468073, Length=319, Percent_Identity=21.6300940438871, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21361693, Length=111, Percent_Identity=32.4324324324324, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI6005715, Length=166, Percent_Identity=27.1084337349398, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI197276625, Length=117, Percent_Identity=31.6239316239316, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=483, Percent_Identity=25.879917184265, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71995588, Length=384, Percent_Identity=25.2604166666667, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25146584, Length=409, Percent_Identity=24.6943765281174, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17542050, Length=136, Percent_Identity=33.8235294117647, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=139, Percent_Identity=31.6546762589928, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212642127, Length=118, Percent_Identity=34.7457627118644, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555248, Length=120, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19921352, Length=423, Percent_Identity=25.0591016548463, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24584353, Length=423, Percent_Identity=25.0591016548463, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281365034, Length=418, Percent_Identity=25.1196172248804, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24652942, Length=392, Percent_Identity=25, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI45551088, Length=392, Percent_Identity=25, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24762620, Length=389, Percent_Identity=25.4498714652956, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI45550877, Length=395, Percent_Identity=25.8227848101266, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639514, Length=509, Percent_Identity=22.9862475442043, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI221329674, Length=509, Percent_Identity=22.9862475442043, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI45551183, Length=395, Percent_Identity=24.8101265822785, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24661428, Length=495, Percent_Identity=21.4141414141414, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281364136, Length=515, Percent_Identity=22.7184466019417, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639516, Length=302, Percent_Identity=24.8344370860927, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19921936, Length=396, Percent_Identity=25, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363702, Length=479, Percent_Identity=24.4258872651357, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136952, Length=384, Percent_Identity=22.3958333333333, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24655079, Length=301, Percent_Identity=25.2491694352159, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281364394, Length=386, Percent_Identity=22.279792746114, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28574704, Length=386, Percent_Identity=22.279792746114, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17136950, Length=386, Percent_Identity=22.279792746114, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28574702, Length=386, Percent_Identity=22.279792746114, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24639853, Length=408, Percent_Identity=23.2843137254902, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24654186, Length=324, Percent_Identity=25.3086419753086, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49672; Mature: 49541

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTGNRESFSSRLGFILSAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPML
CCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH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HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]