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The map label for this gene is yeiG [H]

Identifier: 209694333

GI number: 209694333

Start: 831701

End: 832543

Strand: Reverse

Name: yeiG [H]

Synonym: VSAL_I0745

Alternate gene names: 209694333

Gene position: 832543-831701 (Counterclockwise)

Preceding gene: 209694334

Following gene: 209694332

Centisome position: 25.04

GC content: 39.74

Gene sequence:

>843_bases
ATGACAGTTGAAAACATTAGCCAAGCCAAAGTTGCCGGTGGTTGGCACAAACAATATACACATACATCATCCACACTAAA
TTGCGATATGCGCTTTGCTATCTTCCTACCAGCCAACGCCTCTGAAAGTAATCCGGTTCCTGTTTTATACTGGTTATCAG
GCTTAACGTGTACTGATGAAAACTTCATGCAAAAAGCGGGCGCTTTCAAAAAAGCAGCTGAATTAGGCATTGCAATTGTC
GCTATGGATACAAGCCCACGTGGTGAAGATGTTGATGATGATGCAGAAGGTGCCTACGATTTTGGTCTAGGTGCTGGATT
CTACTTAAATGCAACTCAAGCGCCATGGAATCGTCATTACCATATGTATGATTACGTAACAAAAGAGCTGCCATCTTTAA
TTGAAGAGCACTTCCCTGTATCAGATAAAAAATCGATTTCTGGTCACAGCATGGGTGGTCATGGTGCAATTACCATTGGC
TTGAAAAACCAAGATGCATATCAGTCTATTTCTGCATTTAGTCCAATATCTAGCCCAATCAATTGCCCTTGGGGTCAAAA
AGCATTAGGTCTATATCTTGGTGATAATAAAGAAACTTGGAAAGAGTACGACAGCTCTGAGCTTCTTAAAAAAGGGTCTA
AACTTCCAATTTTAGTTGACCAAGGTGAAGCTGATGGCTTCTTAGAAGAACAATTAAAACCTGAGTACCTACTTTCTTCA
GCAGAGCAATCAGGCACGAATATAGAAGTAAGAATGCAACCAGGTTACGACCACAGCTATTTCTTTATGTCGACTTTTAT
TGATGAGCACCTAGAATTTCATGCTACTTATTTAAATAAATAA

Upstream 100 bases:

>100_bases
TCTTTTTTCTTTACTTCAAAGCACTTTAAAATCAATCAGTAGATACCTCATTCTATGCAGTGAAATCACTGATATGAATT
AAATATAATAAGGATTCATC

Downstream 100 bases:

>100_bases
TACTGATTTAAGATAAGTAAAAGAATAAGTAGCAAAAATCCCAGAGTAGGTTCTCCTTCTCTGGGATTTTTTATATCTAT
ATATTAATTTAATATAATTA

Product: esterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTVENISQAKVAGGWHKQYTHTSSTLNCDMRFAIFLPANASESNPVPVLYWLSGLTCTDENFMQKAGAFKKAAELGIAIV
AMDTSPRGEDVDDDAEGAYDFGLGAGFYLNATQAPWNRHYHMYDYVTKELPSLIEEHFPVSDKKSISGHSMGGHGAITIG
LKNQDAYQSISAFSPISSPINCPWGQKALGLYLGDNKETWKEYDSSELLKKGSKLPILVDQGEADGFLEEQLKPEYLLSS
AEQSGTNIEVRMQPGYDHSYFFMSTFIDEHLEFHATYLNK

Sequences:

>Translated_280_residues
MTVENISQAKVAGGWHKQYTHTSSTLNCDMRFAIFLPANASESNPVPVLYWLSGLTCTDENFMQKAGAFKKAAELGIAIV
AMDTSPRGEDVDDDAEGAYDFGLGAGFYLNATQAPWNRHYHMYDYVTKELPSLIEEHFPVSDKKSISGHSMGGHGAITIG
LKNQDAYQSISAFSPISSPINCPWGQKALGLYLGDNKETWKEYDSSELLKKGSKLPILVDQGEADGFLEEQLKPEYLLSS
AEQSGTNIEVRMQPGYDHSYFFMSTFIDEHLEFHATYLNK
>Mature_279_residues
TVENISQAKVAGGWHKQYTHTSSTLNCDMRFAIFLPANASESNPVPVLYWLSGLTCTDENFMQKAGAFKKAAELGIAIVA
MDTSPRGEDVDDDAEGAYDFGLGAGFYLNATQAPWNRHYHMYDYVTKELPSLIEEHFPVSDKKSISGHSMGGHGAITIGL
KNQDAYQSISAFSPISSPINCPWGQKALGLYLGDNKETWKEYDSSELLKKGSKLPILVDQGEADGFLEEQLKPEYLLSSA
EQSGTNIEVRMQPGYDHSYFFMSTFIDEHLEFHATYLNK

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=283, Percent_Identity=49.469964664311, Blast_Score=293, Evalue=1e-79,
Organism=Escherichia coli, GI1788477, Length=281, Percent_Identity=53.3807829181495, Blast_Score=306, Evalue=8e-85,
Organism=Escherichia coli, GI1786551, Length=278, Percent_Identity=50.7194244604317, Blast_Score=293, Evalue=7e-81,
Organism=Caenorhabditis elegans, GI17510185, Length=288, Percent_Identity=50.3472222222222, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6322393, Length=293, Percent_Identity=44.0273037542662, Blast_Score=236, Evalue=3e-63,
Organism=Drosophila melanogaster, GI45551932, Length=285, Percent_Identity=48.0701754385965, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24648347, Length=286, Percent_Identity=47.9020979020979, Blast_Score=272, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31092; Mature: 30961

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVENISQAKVAGGWHKQYTHTSSTLNCDMRFAIFLPANASESNPVPVLYWLSGLTCTDE
CCCCCCCHHHHCCCCHHHHCCCCCEEEEEEEEEEEEECCCCCCCCCEEEEEECCCEECCH
NFMQKAGAFKKAAELGIAIVAMDTSPRGEDVDDDAEGAYDFGLGAGFYLNATQAPWNRHY
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCE
HMYDYVTKELPSLIEEHFPVSDKKSISGHSMGGHGAITIGLKNQDAYQSISAFSPISSPI
EHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCC
NCPWGQKALGLYLGDNKETWKEYDSSELLKKGSKLPILVDQGEADGFLEEQLKPEYLLSS
CCCCCCCEEEEEECCCHHHHHHCCHHHHHHCCCCCCEEEECCCCCCHHHHHCCHHHHHHH
AEQSGTNIEVRMQPGYDHSYFFMSTFIDEHLEFHATYLNK
HHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVENISQAKVAGGWHKQYTHTSSTLNCDMRFAIFLPANASESNPVPVLYWLSGLTCTDE
CCCCCCHHHHCCCCHHHHCCCCCEEEEEEEEEEEEECCCCCCCCCEEEEEECCCEECCH
NFMQKAGAFKKAAELGIAIVAMDTSPRGEDVDDDAEGAYDFGLGAGFYLNATQAPWNRHY
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCE
HMYDYVTKELPSLIEEHFPVSDKKSISGHSMGGHGAITIGLKNQDAYQSISAFSPISSPI
EHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCC
NCPWGQKALGLYLGDNKETWKEYDSSELLKKGSKLPILVDQGEADGFLEEQLKPEYLLSS
CCCCCCCEEEEEECCCHHHHHHCCHHHHHHCCCCCCEEEECCCCCCHHHHHCCHHHHHHH
AEQSGTNIEVRMQPGYDHSYFFMSTFIDEHLEFHATYLNK
HHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA