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The map label for this gene is serB [H]

Identifier: 209694215

GI number: 209694215

Start: 686566

End: 687534

Strand: Direct

Name: serB [H]

Synonym: VSAL_I0624

Alternate gene names: 209694215

Gene position: 686566-687534 (Clockwise)

Preceding gene: 209694213

Following gene: 209694217

Centisome position: 20.65

GC content: 40.45

Gene sequence:

>969_bases
ATGGACGCGATAACCCCATTTGCAATAAAGAAACACACAACACTGGTAAACCGTTTTTCAACCTCGGTAACGGCCTCTCA
ATTAGAGGTTAAGTCAGTGGGTTGGATCATTTACGGTTCACACCTTTCTCCCCTTCACACTAAAGATATCTATTTTTTTG
TTGGAATGACAACAAAGGTCATTCGAACATGGAAAGTGGGTGACTATGAAGTCGCTGCTATCGCTGGTGAAATGACACCA
GAACACAAAATCATCGTTGATGAACTCGGTTTAGATTACGCTGAAATAAAAGACATCCCCGATTTATCTAATCCGGGAAT
TATCCTTTTTGATATGGATTCAACAACCATTGAAATTGAATGCATTGATGAAATAGCGAAATTGGCAGGGGTTGGTGAGC
AAGTATCTGAAGTGACAGAGCGAGCGATGCTAGGTGAACTTGATTTTAAAGAAAGCTTAATTCAACGAGTGAGTACTCTT
GAAGGAGCAAGTGAATCGATTCTGGCTCAAGTCAAAGAAACCCTTCCTTTTATGCCTGAGATGAGAGAATTGGTAATGAC
AATGCAGAACTATGGTTGGAAAGTCGCTATAGCATCTGGTGGATTTACTTACTTTTCAGATTACCTTAAAGAAGAGTTGA
ATTTAGTTCACGCTCAATCAAACCAGTTAGAAATCATTGACGGTAAATTAACGGGTAAGGTTTTAGGTGATATTGTTAGC
GCAGAAACCAAAGCCGATATTCTTATTGAACTGGCAGATAAGTACGACATTGAAATGAGTAATACGGTTGCGGTTGGTGA
TGGAGCTAATGACTTAGTCATGATGTCAGCAGCAGGTCTGGGCATTGCTTATCATGCAAAACCTAAAGTACAAGAGCAAG
CACAGGCAGCGGTTCGATACGCAGATTTAGGTGGCGTTGCTTGTATCCTTTCAGCTTCGCTACTAATGAATAATAAGCTG
AGTTGGTAA

Upstream 100 bases:

>100_bases
ATACGCAATTTATACAAAAATAGCAGTTTATGTCGCTTCAGACTTGCTCTATCTAATTTCAATCGGTATTTTTGATAGAG
GATTAGTAAGGATACAAATC

Downstream 100 bases:

>100_bases
GTTTATATGAGATGGGTTCTTAACTAGAACCCATTTTTATTAATGCGTAGTATTTACCCTAACTCTAATCGAATAAGTAC
TTCATCGGTAATATCGGTAA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MDAITPFAIKKHTTLVNRFSTSVTASQLEVKSVGWIIYGSHLSPLHTKDIYFFVGMTTKVIRTWKVGDYEVAAIAGEMTP
EHKIIVDELGLDYAEIKDIPDLSNPGIILFDMDSTTIEIECIDEIAKLAGVGEQVSEVTERAMLGELDFKESLIQRVSTL
EGASESILAQVKETLPFMPEMRELVMTMQNYGWKVAIASGGFTYFSDYLKEELNLVHAQSNQLEIIDGKLTGKVLGDIVS
AETKADILIELADKYDIEMSNTVAVGDGANDLVMMSAAGLGIAYHAKPKVQEQAQAAVRYADLGGVACILSASLLMNNKL
SW

Sequences:

>Translated_322_residues
MDAITPFAIKKHTTLVNRFSTSVTASQLEVKSVGWIIYGSHLSPLHTKDIYFFVGMTTKVIRTWKVGDYEVAAIAGEMTP
EHKIIVDELGLDYAEIKDIPDLSNPGIILFDMDSTTIEIECIDEIAKLAGVGEQVSEVTERAMLGELDFKESLIQRVSTL
EGASESILAQVKETLPFMPEMRELVMTMQNYGWKVAIASGGFTYFSDYLKEELNLVHAQSNQLEIIDGKLTGKVLGDIVS
AETKADILIELADKYDIEMSNTVAVGDGANDLVMMSAAGLGIAYHAKPKVQEQAQAAVRYADLGGVACILSASLLMNNKL
SW
>Mature_322_residues
MDAITPFAIKKHTTLVNRFSTSVTASQLEVKSVGWIIYGSHLSPLHTKDIYFFVGMTTKVIRTWKVGDYEVAAIAGEMTP
EHKIIVDELGLDYAEIKDIPDLSNPGIILFDMDSTTIEIECIDEIAKLAGVGEQVSEVTERAMLGELDFKESLIQRVSTL
EGASESILAQVKETLPFMPEMRELVMTMQNYGWKVAIASGGFTYFSDYLKEELNLVHAQSNQLEIIDGKLTGKVLGDIVS
AETKADILIELADKYDIEMSNTVAVGDGANDLVMMSAAGLGIAYHAKPKVQEQAQAAVRYADLGGVACILSASLLMNNKL
SW

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI1790849, Length=281, Percent_Identity=54.4483985765125, Blast_Score=314, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI115534454, Length=173, Percent_Identity=32.3699421965318, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=173, Percent_Identity=32.3699421965318, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=43.2038834951456, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35236; Mature: 35236

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAITPFAIKKHTTLVNRFSTSVTASQLEVKSVGWIIYGSHLSPLHTKDIYFFVGMTTKV
CCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEEEEEECCCCCCCCCCCEEEEEECHHHE
IRTWKVGDYEVAAIAGEMTPEHKIIVDELGLDYAEIKDIPDLSNPGIILFDMDSTTIEIE
EEEECCCCEEEEEEECCCCCCCEEEEHHHCCCHHHHCCCCCCCCCCEEEEECCCCEEEEE
CIDEIAKLAGVGEQVSEVTERAMLGELDFKESLIQRVSTLEGASESILAQVKETLPFMPE
EHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
MRELVMTMQNYGWKVAIASGGFTYFSDYLKEELNLVHAQSNQLEIIDGKLTGKVLGDIVS
HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHHH
AETKADILIELADKYDIEMSNTVAVGDGANDLVMMSAAGLGIAYHAKPKVQEQAQAAVRY
CCCCHHEEEEECCCCCEEECCEEEECCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHH
ADLGGVACILSASLLMNNKLSW
HHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDAITPFAIKKHTTLVNRFSTSVTASQLEVKSVGWIIYGSHLSPLHTKDIYFFVGMTTKV
CCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEEEEEECCCCCCCCCCCEEEEEECHHHE
IRTWKVGDYEVAAIAGEMTPEHKIIVDELGLDYAEIKDIPDLSNPGIILFDMDSTTIEIE
EEEECCCCEEEEEEECCCCCCCEEEEHHHCCCHHHHCCCCCCCCCCEEEEECCCCEEEEE
CIDEIAKLAGVGEQVSEVTERAMLGELDFKESLIQRVSTLEGASESILAQVKETLPFMPE
EHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
MRELVMTMQNYGWKVAIASGGFTYFSDYLKEELNLVHAQSNQLEIIDGKLTGKVLGDIVS
HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHHH
AETKADILIELADKYDIEMSNTVAVGDGANDLVMMSAAGLGIAYHAKPKVQEQAQAAVRY
CCCCHHEEEEECCCCCEEECCEEEECCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHH
ADLGGVACILSASLLMNNKLSW
HHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]