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The map label for this gene is nhaR [H]

Identifier: 209694167

GI number: 209694167

Start: 632642

End: 633583

Strand: Direct

Name: nhaR [H]

Synonym: VSAL_I0575

Alternate gene names: 209694167

Gene position: 632642-633583 (Clockwise)

Preceding gene: 209694165

Following gene: 209694168

Centisome position: 19.03

GC content: 37.26

Gene sequence:

>942_bases
ATGACGTATCTTTTGGAAAAGATCAATGTAGGAACCGTTATGTCACATTTAAACTATAACCATCTTTATTATTTTTGGAT
GGTGTGCAAACAAGGATCGGTAACTAAAGCTGCTGAAGCATTATTTTTAACGCCTCAAACGGTGACTGGACAAATCAAGG
CATTGGAAGAACGCGTTGATGGCAAATTAACGAAACGTAATGGACGTAACATTGAGCCAACAGAATTAGGGCAATTAATT
TATAAATACGCCGATCGTATGTTTGGCCTTAGTTATGAGATGTTAGATATCGTTAATTATAGTCAACAATCAAATGTGCT
ATTTGATGTTGGCGTTGCTGATGCTCTTTCTAAACGATTAGTGAGTAAAGTTCTTTCAACCACGATTCCTGAAGATGCAT
CAATACATCTTCGCTGCTTTGAATCGACCCATGAATTGCTACTTGAACAGTTATCTCAGCATAAATTAGATATGATCTTA
TCGGATTGCCCTGTTGACTCAAGCCAGAATTCTGGACTTTTCAGCAAAAAATTGGGTGAATGTGGAATGAGTTTTTTCTG
CTCTAAAGAAATGACGGATATTCAATTCCCAGAAGTATTAGAGATAAAAAAGGTACTGATCCCTGGCAGTCGAACATCAA
TGGGAAGAAAGGTGGTTCAGTGGTGCGATCAGCAAGGTATTACGCCTAATATCTTAGGGGAATTTGATGACGTTGCTCTA
ATGAAGGCCTTTGCCCGTGAGAATGACTCTGTATTTTTAGCCCCAACGGTTTATATGAATGAGGCTGATTCTGATCTTTC
TTTGCACCGAATCGCTGACGTAAAAGATTTAAAAGAAGAATATTACGTTATTTTTGCAGAACGAATGATTCAGCATCCGG
CAGTAAAAAGTATTTGTGAAGCTGATTTTTCACAGTTATTTGATTTTAATTTGCAAAAATAG

Upstream 100 bases:

>100_bases
TTGCGTAAAGATGACGTTTATAATAATTTGAATACGGAATATCCGATGTTTTTGGTGTTTTGTTGTACTTTTTACGAAAT
GAATGTCTTCGTTGTCATAA

Downstream 100 bases:

>100_bases
AATGCTTTAAGCTAAATTAGCAGGAACTAAATTAGATGGCAGGTATATTTATGGATTTACAACAAATGGAGAAAAACGCT
CCGCAAGCAGTCACACTACT

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTYLLEKINVGTVMSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERVDGKLTKRNGRNIEPTELGQLI
YKYADRMFGLSYEMLDIVNYSQQSNVLFDVGVADALSKRLVSKVLSTTIPEDASIHLRCFESTHELLLEQLSQHKLDMIL
SDCPVDSSQNSGLFSKKLGECGMSFFCSKEMTDIQFPEVLEIKKVLIPGSRTSMGRKVVQWCDQQGITPNILGEFDDVAL
MKAFARENDSVFLAPTVYMNEADSDLSLHRIADVKDLKEEYYVIFAERMIQHPAVKSICEADFSQLFDFNLQK

Sequences:

>Translated_313_residues
MTYLLEKINVGTVMSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERVDGKLTKRNGRNIEPTELGQLI
YKYADRMFGLSYEMLDIVNYSQQSNVLFDVGVADALSKRLVSKVLSTTIPEDASIHLRCFESTHELLLEQLSQHKLDMIL
SDCPVDSSQNSGLFSKKLGECGMSFFCSKEMTDIQFPEVLEIKKVLIPGSRTSMGRKVVQWCDQQGITPNILGEFDDVAL
MKAFARENDSVFLAPTVYMNEADSDLSLHRIADVKDLKEEYYVIFAERMIQHPAVKSICEADFSQLFDFNLQK
>Mature_312_residues
TYLLEKINVGTVMSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERVDGKLTKRNGRNIEPTELGQLIY
KYADRMFGLSYEMLDIVNYSQQSNVLFDVGVADALSKRLVSKVLSTTIPEDASIHLRCFESTHELLLEQLSQHKLDMILS
DCPVDSSQNSGLFSKKLGECGMSFFCSKEMTDIQFPEVLEIKKVLIPGSRTSMGRKVVQWCDQQGITPNILGEFDDVALM
KAFARENDSVFLAPTVYMNEADSDLSLHRIADVKDLKEEYYVIFAERMIQHPAVKSICEADFSQLFDFNLQK

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=294, Percent_Identity=62.9251700680272, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=22.6337448559671, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI157672245, Length=250, Percent_Identity=21.6, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35564; Mature: 35433

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLLEKINVGTVMSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERVD
CCHHHHHCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHEECCCHHHHHHHHHHHHHC
GKLTKRNGRNIEPTELGQLIYKYADRMFGLSYEMLDIVNYSQQSNVLFDVGVADALSKRL
CCEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHH
VSKVLSTTIPEDASIHLRCFESTHELLLEQLSQHKLDMILSDCPVDSSQNSGLFSKKLGE
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
CGMSFFCSKEMTDIQFPEVLEIKKVLIPGSRTSMGRKVVQWCDQQGITPNILGEFDDVAL
HCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHH
MKAFARENDSVFLAPTVYMNEADSDLSLHRIADVKDLKEEYYVIFAERMIQHPAVKSICE
HHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
ADFSQLFDFNLQK
HHHHHHHCCCCCC
>Mature Secondary Structure 
TYLLEKINVGTVMSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERVD
CHHHHHCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHEECCCHHHHHHHHHHHHHC
GKLTKRNGRNIEPTELGQLIYKYADRMFGLSYEMLDIVNYSQQSNVLFDVGVADALSKRL
CCEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHH
VSKVLSTTIPEDASIHLRCFESTHELLLEQLSQHKLDMILSDCPVDSSQNSGLFSKKLGE
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
CGMSFFCSKEMTDIQFPEVLEIKKVLIPGSRTSMGRKVVQWCDQQGITPNILGEFDDVAL
HCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHH
MKAFARENDSVFLAPTVYMNEADSDLSLHRIADVKDLKEEYYVIFAERMIQHPAVKSICE
HHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
ADFSQLFDFNLQK
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]