Click here to switch to the map view.

The map label for this gene is cysC [H]

Identifier: 209694024

GI number: 209694024

Start: 460572

End: 461204

Strand: Direct

Name: cysC [H]

Synonym: VSAL_I0423

Alternate gene names: 209694024

Gene position: 460572-461204 (Clockwise)

Preceding gene: 209694023

Following gene: 209694032

Centisome position: 13.85

GC content: 39.02

Gene sequence:

>633_bases
ATGACTACGGAACAAACGAAAGAGCGCCAAGTAGTGAACGATGAAAATGTGGTTTGGCATCAATATTCGGTGACAAAAGA
AACTCGCTCTGGTCTTAAAAAACAAAAGCCAGTGGTTCTTTGGTTTACGGGATTATCGGGAGCGGGTAAATCAACCATTG
CTGGTGCATTGGAGGTGAAGCTTGCCGAACTTGGTTATCACACGTATTTATTGGATGGTGATAATGTTCGTCATGGTTTA
TGTAAAGATTTAGGCTTTTCTGATCACGATAGGCAAGAAAATATTCGTCGTATTGGCGAGTTGGCAAAATTGATGTCTGA
TGCGGGGTTAATCGTATTAAGCGCCTTTATTTCACCGCATCGAGCGGAAAGACAAATAGTCAGAGAGTTATTGCCTGAAA
ATGAATTCTTAGAAGTGTTTGTCAATACATCACTTGATGAATGTGAAAAACGAGACCCAAAAGGATTATACAAAAAAGCA
CGGGCAGGAGAGATAAAACATTTCACGGGGATTGATTCTGATTATGAACAACCGCTAAATCCTGATATTGATTTATTGGC
AGGTACACAATCGATTGATGAACTAGTGGAGCAATGCTTGGCGGTATTAAAAGAAAAAAATATTATTCAATAA

Upstream 100 bases:

>100_bases
TCGATTACGTAAAAGTAGGGTTGCCAATGTCAATTATTTATTCGGTGTTAGTGCTGTCTTTAATCCCTCACTTTTTCCCA
TTTTAATTCAAGGATGATAT

Downstream 100 bases:

>100_bases
GCACAAGCAGCAGGAGATGTTTTTCTTCCTGCTGTTTGTGATGCTATACCATGGTTGATATTGATGTTTTTACATCAGTT
TCAACCATGAATTTTTGGCT

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTTEQTKERQVVNDENVVWHQYSVTKETRSGLKKQKPVVLWFTGLSGAGKSTIAGALEVKLAELGYHTYLLDGDNVRHGL
CKDLGFSDHDRQENIRRIGELAKLMSDAGLIVLSAFISPHRAERQIVRELLPENEFLEVFVNTSLDECEKRDPKGLYKKA
RAGEIKHFTGIDSDYEQPLNPDIDLLAGTQSIDELVEQCLAVLKEKNIIQ

Sequences:

>Translated_210_residues
MTTEQTKERQVVNDENVVWHQYSVTKETRSGLKKQKPVVLWFTGLSGAGKSTIAGALEVKLAELGYHTYLLDGDNVRHGL
CKDLGFSDHDRQENIRRIGELAKLMSDAGLIVLSAFISPHRAERQIVRELLPENEFLEVFVNTSLDECEKRDPKGLYKKA
RAGEIKHFTGIDSDYEQPLNPDIDLLAGTQSIDELVEQCLAVLKEKNIIQ
>Mature_209_residues
TTEQTKERQVVNDENVVWHQYSVTKETRSGLKKQKPVVLWFTGLSGAGKSTIAGALEVKLAELGYHTYLLDGDNVRHGLC
KDLGFSDHDRQENIRRIGELAKLMSDAGLIVLSAFISPHRAERQIVRELLPENEFLEVFVNTSLDECEKRDPKGLYKKAR
AGEIKHFTGIDSDYEQPLNPDIDLLAGTQSIDELVEQCLAVLKEKNIIQ

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI34447231, Length=206, Percent_Identity=48.5436893203884, Blast_Score=187, Evalue=5e-48,
Organism=Homo sapiens, GI62912492, Length=206, Percent_Identity=48.5436893203884, Blast_Score=187, Evalue=5e-48,
Organism=Homo sapiens, GI46094058, Length=206, Percent_Identity=47.0873786407767, Blast_Score=185, Evalue=3e-47,
Organism=Escherichia coli, GI1789107, Length=199, Percent_Identity=63.8190954773869, Blast_Score=259, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI17542422, Length=200, Percent_Identity=50.5, Blast_Score=196, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6322852, Length=192, Percent_Identity=48.9583333333333, Blast_Score=183, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24667032, Length=215, Percent_Identity=43.7209302325581, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24667028, Length=215, Percent_Identity=43.7209302325581, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24667036, Length=215, Percent_Identity=43.7209302325581, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI116007838, Length=200, Percent_Identity=45, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667044, Length=200, Percent_Identity=45, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667040, Length=200, Percent_Identity=45, Blast_Score=172, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 23676; Mature: 23545

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEQTKERQVVNDENVVWHQYSVTKETRSGLKKQKPVVLWFTGLSGAGKSTIAGALEVK
CCCCCCHHHHHCCCCCEEEEEHHCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
LAELGYHTYLLDGDNVRHGLCKDLGFSDHDRQENIRRIGELAKLMSDAGLIVLSAFISPH
HHHCCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
RAERQIVRELLPENEFLEVFVNTSLDECEKRDPKGLYKKARAGEIKHFTGIDSDYEQPLN
HHHHHHHHHHCCCCCEEHHHHCCCHHHHHCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCC
PDIDLLAGTQSIDELVEQCLAVLKEKNIIQ
CCHHEEECCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTEQTKERQVVNDENVVWHQYSVTKETRSGLKKQKPVVLWFTGLSGAGKSTIAGALEVK
CCCCCHHHHHCCCCCEEEEEHHCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
LAELGYHTYLLDGDNVRHGLCKDLGFSDHDRQENIRRIGELAKLMSDAGLIVLSAFISPH
HHHCCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
RAERQIVRELLPENEFLEVFVNTSLDECEKRDPKGLYKKARAGEIKHFTGIDSDYEQPLN
HHHHHHHHHHCCCCCEEHHHHCCCHHHHHCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCC
PDIDLLAGTQSIDELVEQCLAVLKEKNIIQ
CCHHEEECCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]