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The map label for this gene is surA [H]

Identifier: 209693973

GI number: 209693973

Start: 404018

End: 405328

Strand: Reverse

Name: surA [H]

Synonym: VSAL_I0370

Alternate gene names: 209693973

Gene position: 405328-404018 (Counterclockwise)

Preceding gene: 209693974

Following gene: 209693972

Centisome position: 12.19

GC content: 39.59

Gene sequence:

>1311_bases
ATGAAAAACTGGAAAATTCCATTTATTAGCAGTTTATTACTAATGCTGACAATAAATGTACATGCCGCTCCCGTAGAGCT
TGATCGCGTTATTGCCATTGTTGACGAAGGCGTTGTATTACAAAGTGATATTGAAACTTCATTAAAAACAGTAAAAATCA
ATGCTCAAGAAAAAGGACAACCTTTACCTGAAGAAAACGTGCTGCGTGAACAAGTATTAGAAAAATTGATTCTTGATACT
ATTCAAAGTCAACAAGCGGAAAAAATGGGTATTCGTATTGACGATACTCGTTTAGAAGAAGCCTTAAACAATATAGCAAA
AGACAACAAAATGACCTTGGCGCAGTTACAACAAAAAGCGGCCTCTCAAGGTCTCGCTTATGCCGACTTCCGCGAACAAA
TTCGTAAAGAAATTGCAGCAAGTGAAGCTCGTAATGCACAAGTTCGTCGTCGTATTAATATTCTACCTCAAGAAGTAGAA
AGCCTTGCTCTGTTACTTTCGGAAGAAACTCAAGCGACAGTCCAATACAAAATCAGCCATATTCAATTGCGTACTGATGG
TGCCACTCAAGCAGAAAAAGAAGCTCTAGAAAAACAAGCTCTAGAACTGACTGAACGCTTAAAACAAGGCGCTGATTTTG
CAACAATGGCGTATACCTATTCTAAAGGACCAAAAGCACTGCAAGGCGGTGATTGGGGTTGGATGAGAAAAGAAGAAATG
CCAACGATTTTTGCTGATCAAATTACAGGTCAAGGAAAAAGCAGCATCATTGGCCCATTCCGCTCTGGTGTTGGTTTTCA
TATTATAAAGATTGACGATGTAAAAGGCCTAGAGACCGTTGCGGTTACTGAAGTAAACGCTCGTCATATCTTAGTTAAAA
CATCGGTTATAATGAGTGATGAAGGCGCAGAGCGACTATTGAACCAAATCACTTCAGACATAGAATCAGGAAAAGAAACA
TTTGCCGCTATGGCTCAACGTTATAGCCAAGATCCAGGTTCGGCAGCCGCAAATGGAGAATTAGGTTTCCAGACTCCAGA
CCTATATGTTCCAGAATTTAAACATCAAGTTGAAATTCTACCTGTTGGCCAAATAAGTAAGCCATTTAAAACCGTTCATG
GTTGGCATATTGCTGAAGTATTAGAGCGTCGCCAAGTTGATAGAACCGATGCAGCGATGAAAAACAAAGCTTATCGAATT
CTAATGAATCGCAAGTTTAACGAAGAGTCAGGCGCTTGGTTACAAGAAATCAGAGCGAGTGCTTACGTCGAAATTCTGCA
AGATAATGATGACAGTGATGAAAATGAATAA

Upstream 100 bases:

>100_bases
TATGGTCGCCCATTCTATTTAAATAATTAATTATAGGGACACGAGTTAACGCTAACGGATATCGCTATCGTTAACTCTCT
ATACACTCTTGGATGACACT

Downstream 100 bases:

>100_bases
TATAAAACGCATAGCAATCACACCGGGAGAACCCGCGGGCATCGGCCCTGATCTTGTTCTGTCTATTGCTCAACAAGATT
GGCCTCATCAATTGGTTATC

Product: chaperone SurA precursor

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKNWKIPFISSLLLMLTINVHAAPVELDRVIAIVDEGVVLQSDIETSLKTVKINAQEKGQPLPEENVLREQVLEKLILDT
IQSQQAEKMGIRIDDTRLEEALNNIAKDNKMTLAQLQQKAASQGLAYADFREQIRKEIAASEARNAQVRRRINILPQEVE
SLALLLSEETQATVQYKISHIQLRTDGATQAEKEALEKQALELTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEEM
PTIFADQITGQGKSSIIGPFRSGVGFHIIKIDDVKGLETVAVTEVNARHILVKTSVIMSDEGAERLLNQITSDIESGKET
FAAMAQRYSQDPGSAAANGELGFQTPDLYVPEFKHQVEILPVGQISKPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYRI
LMNRKFNEESGAWLQEIRASAYVEILQDNDDSDENE

Sequences:

>Translated_436_residues
MKNWKIPFISSLLLMLTINVHAAPVELDRVIAIVDEGVVLQSDIETSLKTVKINAQEKGQPLPEENVLREQVLEKLILDT
IQSQQAEKMGIRIDDTRLEEALNNIAKDNKMTLAQLQQKAASQGLAYADFREQIRKEIAASEARNAQVRRRINILPQEVE
SLALLLSEETQATVQYKISHIQLRTDGATQAEKEALEKQALELTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEEM
PTIFADQITGQGKSSIIGPFRSGVGFHIIKIDDVKGLETVAVTEVNARHILVKTSVIMSDEGAERLLNQITSDIESGKET
FAAMAQRYSQDPGSAAANGELGFQTPDLYVPEFKHQVEILPVGQISKPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYRI
LMNRKFNEESGAWLQEIRASAYVEILQDNDDSDENE
>Mature_436_residues
MKNWKIPFISSLLLMLTINVHAAPVELDRVIAIVDEGVVLQSDIETSLKTVKINAQEKGQPLPEENVLREQVLEKLILDT
IQSQQAEKMGIRIDDTRLEEALNNIAKDNKMTLAQLQQKAASQGLAYADFREQIRKEIAASEARNAQVRRRINILPQEVE
SLALLLSEETQATVQYKISHIQLRTDGATQAEKEALEKQALELTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEEM
PTIFADQITGQGKSSIIGPFRSGVGFHIIKIDDVKGLETVAVTEVNARHILVKTSVIMSDEGAERLLNQITSDIESGKET
FAAMAQRYSQDPGSAAANGELGFQTPDLYVPEFKHQVEILPVGQISKPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYRI
LMNRKFNEESGAWLQEIRASAYVEILQDNDDSDENE

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=430, Percent_Identity=47.6744186046512, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48866; Mature: 48866

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWKIPFISSLLLMLTINVHAAPVELDRVIAIVDEGVVLQSDIETSLKTVKINAQEKGQ
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECHHHCCEEEEEECCHHCCC
PLPEENVLREQVLEKLILDTIQSQQAEKMGIRIDDTRLEEALNNIAKDNKMTLAQLQQKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHH
ASQGLAYADFREQIRKEIAASEARNAQVRRRINILPQEVESLALLLSEETQATVQYKISH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHEEEEEEEE
IQLRTDGATQAEKEALEKQALELTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEEM
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHCC
PTIFADQITGQGKSSIIGPFRSGVGFHIIKIDDVKGLETVAVTEVNARHILVKTSVIMSD
CCHHHHHHCCCCCCCCCCHHHCCCCEEEEEEECCCCCCEEEEEECCCCEEEEEEEEEECC
EGAERLLNQITSDIESGKETFAAMAQRYSQDPGSAAANGELGFQTPDLYVPEFKHQVEIL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
PVGQISKPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYRILMNRKFNEESGAWLQEIRAS
ECCCCCCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
AYVEILQDNDDSDENE
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKNWKIPFISSLLLMLTINVHAAPVELDRVIAIVDEGVVLQSDIETSLKTVKINAQEKGQ
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECHHHCCEEEEEECCHHCCC
PLPEENVLREQVLEKLILDTIQSQQAEKMGIRIDDTRLEEALNNIAKDNKMTLAQLQQKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHH
ASQGLAYADFREQIRKEIAASEARNAQVRRRINILPQEVESLALLLSEETQATVQYKISH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHEEEEEEEE
IQLRTDGATQAEKEALEKQALELTERLKQGADFATMAYTYSKGPKALQGGDWGWMRKEEM
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHCC
PTIFADQITGQGKSSIIGPFRSGVGFHIIKIDDVKGLETVAVTEVNARHILVKTSVIMSD
CCHHHHHHCCCCCCCCCCHHHCCCCEEEEEEECCCCCCEEEEEECCCCEEEEEEEEEECC
EGAERLLNQITSDIESGKETFAAMAQRYSQDPGSAAANGELGFQTPDLYVPEFKHQVEIL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
PVGQISKPFKTVHGWHIAEVLERRQVDRTDAAMKNKAYRILMNRKFNEESGAWLQEIRAS
ECCCCCCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
AYVEILQDNDDSDENE
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA