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The map label for this gene is purE [H]

Identifier: 209693705

GI number: 209693705

Start: 83673

End: 84209

Strand: Reverse

Name: purE [H]

Synonym: VSAL_I0081

Alternate gene names: 209693705

Gene position: 84209-83673 (Counterclockwise)

Preceding gene: 209693709

Following gene: 209693704

Centisome position: 2.53

GC content: 43.2

Gene sequence:

>537_bases
ATGCTGCCAACTTTTTATATATTGCCATTATCTTTATCCAAGGAGTTCACAATGAAAGTCGGTATTATCATGGGTTCGAA
ATCAGATTGGCCAACAATGAAACTAGCCGCTGAAATGCTTGAGCGTTTTAATGTTCCTTACGAAACCAAAGTGGTCTCTG
CTCATAGAACTCCACAATTACTTGCTGATTATGCAACTCAAGCAAAAGATCGCGGTATCAAAGTTATTATTGCAGGTGCT
GGTGGTGCCGCTCACCTCCCAGGCATGGCAGCTGCATTTACGAGTATTCCTGTTTTAGGCGTCCCTGTTCAATCAAAAGT
ATTAAAAGGGATAGACTCTCTACTTTCTATCGTTCAAATGCCAAAGGGGATCGCTGTAGGTACACTCGCGATAGGTGAGG
CTGGCGCTGCAAATGCAGGTATCCTCGCAGCTCAAATCATTGGTACGTCAAATGAAGCAGTAATGGCAGCAGTAGAAGCC
TTCCGTAAAGAACAAACAGATACTGTCTTAGCAAATCCAGATCCATCAGAGGATTAA

Upstream 100 bases:

>100_bases
AAATCAAACAACCGCTTTCCATTTTTCAATTGTGAATAATCGTTAATAACTTGTACTTTTCCTAACGCAAACGTTTTCCT
TCCTATTAAATAACCGTATA

Downstream 100 bases:

>100_bases
TGATGAAAGTTCTTGTACTCGGTTCTGGTCAACTCGCTCGCATGATGTCTTTAGCGAGTGCTCCACTAAATATCGACATT
ATCGCTTATGATGTGAACAA

Product: phosphoribosylaminoimidazole carboxylase catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MLPTFYILPLSLSKEFTMKVGIIMGSKSDWPTMKLAAEMLERFNVPYETKVVSAHRTPQLLADYATQAKDRGIKVIIAGA
GGAAHLPGMAAAFTSIPVLGVPVQSKVLKGIDSLLSIVQMPKGIAVGTLAIGEAGAANAGILAAQIIGTSNEAVMAAVEA
FRKEQTDTVLANPDPSED

Sequences:

>Translated_178_residues
MLPTFYILPLSLSKEFTMKVGIIMGSKSDWPTMKLAAEMLERFNVPYETKVVSAHRTPQLLADYATQAKDRGIKVIIAGA
GGAAHLPGMAAAFTSIPVLGVPVQSKVLKGIDSLLSIVQMPKGIAVGTLAIGEAGAANAGILAAQIIGTSNEAVMAAVEA
FRKEQTDTVLANPDPSED
>Mature_178_residues
MLPTFYILPLSLSKEFTMKVGIIMGSKSDWPTMKLAAEMLERFNVPYETKVVSAHRTPQLLADYATQAKDRGIKVIIAGA
GGAAHLPGMAAAFTSIPVLGVPVQSKVLKGIDSLLSIVQMPKGIAVGTLAIGEAGAANAGILAAQIIGTSNEAVMAAVEA
FRKEQTDTVLANPDPSED

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=163, Percent_Identity=61.9631901840491, Blast_Score=171, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324702, Length=151, Percent_Identity=52.9801324503311, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 18606; Mature: 18606

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPTFYILPLSLSKEFTMKVGIIMGSKSDWPTMKLAAEMLERFNVPYETKVVSAHRTPQL
CCCEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEECCCCHHH
LADYATQAKDRGIKVIIAGAGGAAHLPGMAAAFTSIPVLGVPVQSKVLKGIDSLLSIVQM
HHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHC
PKGIAVGTLAIGEAGAANAGILAAQIIGTSNEAVMAAVEAFRKEQTDTVLANPDPSED
CCCCEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MLPTFYILPLSLSKEFTMKVGIIMGSKSDWPTMKLAAEMLERFNVPYETKVVSAHRTPQL
CCCEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEECCCCHHH
LADYATQAKDRGIKVIIAGAGGAAHLPGMAAAFTSIPVLGVPVQSKVLKGIDSLLSIVQM
HHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHC
PKGIAVGTLAIGEAGAANAGILAAQIIGTSNEAVMAAVEAFRKEQTDTVLANPDPSED
CCCCEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA