BacMap

Definition	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence.
Accession	NC_011370
Length	308,747

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The map label for this gene is lvr [H]

Identifier: 209552120

GI number: 209552120

Start: 215732

End: 216502

Strand: Reverse

Name: lvr [H]

Synonym: Rleg2_6271

Alternate gene names: 209552120

Gene position: 216502-215732 (Counterclockwise)

Preceding gene: 209552121

Following gene: 209552119

Centisome position: 70.12

GC content: 57.46

Gene sequence:

>771_bases
ATGAAAAGGCTTGAAGATAAGGTTGCAATCGTGACCGGGGGTGCGGCGGGAATCGGACTGGGATGCGTGACGCGCCTGCT
GGATGAAGGCGCGTTCGTCGCCATGATTGATCTAGACGAGCGGCGGTGCCTCGCCGCCTCGCGTCAGCTGGCCGCAGAAG
AGGGCCGGCTCAGGACCTACGTTGCCGACGTCGGCAAGGAAGCTGTTATCGCAGAAGCTGTCCGGAATGCTCACCGTGAT
TTCGGAAAAATCGACATCCTCGTGAACAATGCGGGGATCGTGCGGCCGTGGAAATCCACGCACGAAGTTACCGAACAAGA
GTGGGATCAGCTTCAGGCCGTTAACAGCAAGGGTGTGTTCCTTTCCACCAAACATGTGCTTCCGTTCATGATGGAGCAGA
AGTCGGGTGCTATCGTCAACATATCCTCTATCGCCGCCATTCTCTCGTTCGGCGGTATCTCCCCCTATCATGCCGCCAAG
GGCGCGGTGCGGGCGATGACCAAGAACGACGCGATGGATTACGCCAAATACAATATCCGCATCAACGCGGTTCTTCCTGG
TTTCGTTATGACCGATATGGTCCGGGAAGAACTTGAAACACTCTATCCTTCGTACGAGGAAGGCCTGGCCGCCGCCACCG
CCGCGCAGCCGCTCAATTTAATGGGCCAACCTTCGGATATTGCCGCCGCAGTGTGCTTCCTCGCCTCCGAGGATGCCCGA
TACATTACCGGATCAGACATCATAGTTGACGGCGGTTACTCCGCGCGGTGA

Upstream 100 bases:

>100_bases
CCCTGCCGCCGTCCATCAAATCTGTTCGAAGAAGACGTGGTTGGAAAGGCCAGATGCGCCCAGAGTGCCCTGGGGCGAAG
ATCTCGAAAGGAAATGCGGA

Downstream 100 bases:

>100_bases
TGCGACGCTGGCAACAACTGCGTCCTGAACAATTTCAAACCTTAGGCTCAAGTCCGAATCGCGCATGAGGAACACCATGA
AAATCCGATCAATTTCGCTT

Product: short-chain dehydrogenase/reductase SDR

Products: D-Gluconate; Nicotinamide adenine dinucleotide phosphate [C]

Alternate protein names: (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKRLEDKVAIVTGGAAGIGLGCVTRLLDEGAFVAMIDLDERRCLAASRQLAAEEGRLRTYVADVGKEAVIAEAVRNAHRD
FGKIDILVNNAGIVRPWKSTHEVTEQEWDQLQAVNSKGVFLSTKHVLPFMMEQKSGAIVNISSIAAILSFGGISPYHAAK
GAVRAMTKNDAMDYAKYNIRINAVLPGFVMTDMVREELETLYPSYEEGLAAATAAQPLNLMGQPSDIAAAVCFLASEDAR
YITGSDIIVDGGYSAR

Sequences:

>Translated_256_residues
MKRLEDKVAIVTGGAAGIGLGCVTRLLDEGAFVAMIDLDERRCLAASRQLAAEEGRLRTYVADVGKEAVIAEAVRNAHRD
FGKIDILVNNAGIVRPWKSTHEVTEQEWDQLQAVNSKGVFLSTKHVLPFMMEQKSGAIVNISSIAAILSFGGISPYHAAK
GAVRAMTKNDAMDYAKYNIRINAVLPGFVMTDMVREELETLYPSYEEGLAAATAAQPLNLMGQPSDIAAAVCFLASEDAR
YITGSDIIVDGGYSAR
>Mature_256_residues
MKRLEDKVAIVTGGAAGIGLGCVTRLLDEGAFVAMIDLDERRCLAASRQLAAEEGRLRTYVADVGKEAVIAEAVRNAHRD
FGKIDILVNNAGIVRPWKSTHEVTEQEWDQLQAVNSKGVFLSTKHVLPFMMEQKSGAIVNISSIAAILSFGGISPYHAAK
GAVRAMTKNDAMDYAKYNIRINAVLPGFVMTDMVREELETLYPSYEEGLAAATAAQPLNLMGQPSDIAAAVCFLASEDAR
YITGSDIIVDGGYSAR

Specific function: Catalyzes the regio- and stereoselective reversible NAD- dependent reduction of (6R)-2,2,6-trimethyl-1,4-cyclohexanedione (levodione) to (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone (actinol) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=35.9683794466403, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=36.5217391304348, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=33.7254901960784, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=33.8461538461538, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=32.0610687022901, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=31.25, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=32.7935222672065, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=33.0739299610895, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=31.496062992126, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=33.6842105263158, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=35.1351351351351, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4504505, Length=213, Percent_Identity=32.8638497652582, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=30.5164319248826, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=30.3501945525292, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=30.0970873786408, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=39.8058252427184, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=258, Percent_Identity=29.8449612403101, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI210032110, Length=213, Percent_Identity=26.2910798122066, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=30.0492610837438, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI25282469, Length=177, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI83715985, Length=191, Percent_Identity=29.8429319371728, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=30.9941520467836, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=212, Percent_Identity=25, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=34.4, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=34.6303501945525, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=35.3413654618474, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=34.6153846153846, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=32.2709163346614, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=30.9236947791165, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=30.6201550387597, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=30.0395256916996, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=29.004329004329, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367365, Length=262, Percent_Identity=27.8625954198473, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=27.4131274131274, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=37.1647509578544, Blast_Score=137, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=35.4477611940299, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=33.59375, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=34.3396226415094, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=35.1851851851852, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=30.859375, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=33.0882352941176, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=30.5970149253731, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=33.6996336996337, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=33.0909090909091, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=32.421875, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=31.3725490196078, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=29.1970802919708, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=31.2977099236641, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=31.8181818181818, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=30.7392996108949, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=31.8518518518519, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=29.1512915129151, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=29.6703296703297, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=274, Percent_Identity=31.021897810219, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17568967, Length=215, Percent_Identity=34.4186046511628, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=29.7794117647059, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=33.59375, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=30.4832713754647, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=277, Percent_Identity=28.5198555956679, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=30.5882352941176, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=28.158844765343, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=29.6482412060301, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=209, Percent_Identity=28.2296650717703, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=208, Percent_Identity=27.8846153846154, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558006, Length=248, Percent_Identity=29.8387096774194, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559964, Length=209, Percent_Identity=27.7511961722488, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560176, Length=226, Percent_Identity=25.6637168141593, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17541382, Length=214, Percent_Identity=27.1028037383178, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=203, Percent_Identity=30.5418719211823, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=28.957528957529, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=224, Percent_Identity=28.125, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=36.5461847389558, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=34.6153846153846, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=32.6848249027237, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=32.183908045977, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=34.251968503937, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=30.859375, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=33.596837944664, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644337, Length=235, Percent_Identity=31.063829787234, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=32.2916666666667, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355631, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665243, Length=203, Percent_Identity=31.5270935960591, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221331218, Length=203, Percent_Identity=31.5270935960591, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641232, Length=209, Percent_Identity=30.622009569378, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640492, Length=213, Percent_Identity=25.8215962441315, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356301, Length=195, Percent_Identity=31.2820512820513, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=26.8421052631579, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=26.8421052631579, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281364892, Length=169, Percent_Identity=28.9940828402367, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24665247, Length=204, Percent_Identity=31.3725490196078, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221331216, Length=204, Percent_Identity=31.3725490196078, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281364494, Length=208, Percent_Identity=27.4038461538462, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648693, Length=243, Percent_Identity=27.5720164609054, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355889, Length=243, Percent_Identity=27.5720164609054, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641388, Length=215, Percent_Identity=28.3720930232558, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24663911, Length=242, Percent_Identity=26.0330578512397, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=26.2948207171315, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.69 [C]

Molecular weight: Translated: 27584; Mature: 27584

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01108 RIBOSOMAL_L24

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLEDKVAIVTGGAAGIGLGCVTRLLDEGAFVAMIDLDERRCLAASRQLAAEEGRLRTY
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHH
VADVGKEAVIAEAVRNAHRDFGKIDILVNNAGIVRPWKSTHEVTEQEWDQLQAVNSKGVF
HHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCEE
LSTKHVLPFMMEQKSGAIVNISSIAAILSFGGISPYHAAKGAVRAMTKNDAMDYAKYNIR
EECCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEE
INAVLPGFVMTDMVREELETLYPSYEEGLAAATAAQPLNLMGQPSDIAAAVCFLASEDAR
EEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCCC
YITGSDIIVDGGYSAR
EEECCCEEEECCCCCC
>Mature Secondary Structure
MKRLEDKVAIVTGGAAGIGLGCVTRLLDEGAFVAMIDLDERRCLAASRQLAAEEGRLRTY
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHH
VADVGKEAVIAEAVRNAHRDFGKIDILVNNAGIVRPWKSTHEVTEQEWDQLQAVNSKGVF
HHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCEE
LSTKHVLPFMMEQKSGAIVNISSIAAILSFGGISPYHAAKGAVRAMTKNDAMDYAKYNIR
EECCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEE
INAVLPGFVMTDMVREELETLYPSYEEGLAAATAAQPLNLMGQPSDIAAAVCFLASEDAR
EEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCCC
YITGSDIIVDGGYSAR
EEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+; NADH; NADP+; NADPH [C]

Metal ions: Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.02 {NADP+}} 20 {D-gluconate}} 0.006 {NADPH}} 0.9 {5-keto-D-gluconate}} [C]

Substrates: 5-Dehydro-D-gluconate; H+; Nicotinamide adenine dinucleotide phosphate - reduced [C]

Specific reaction: 5-Dehydro-D-gluconate + H+ + Nicotinamide adenine dinucleotide phosphate - reduced <==> D-Gluconate + Nicotinamide adenine dinucleotide phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: Cd2+; Cs2+; Cu2+; Divalent metal ions; Hg2+; Ni2+; p-Chloromercuribenzoate; Sn2+; Sulfhydryl reagents [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11388460; 10508066 [H]