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The map label for this gene is ygjG [C]

Identifier: 209550407

GI number: 209550407

Start: 2876084

End: 2877409

Strand: Direct

Name: ygjG [C]

Synonym: Rleg2_2828

Alternate gene names: 209550407

Gene position: 2876084-2877409 (Clockwise)

Preceding gene: 209550406

Following gene: 209550409

Centisome position: 63.38

GC content: 62.37

Gene sequence:

>1326_bases
ATGTCCAATCGCCTCAACGCACCGAACGATCTTCGCGCCTTCTGGATGCCGTTCACGGCAAATCGCCAGTTCAAACAGGA
GCCGCGTATGTTCGTCGGCGCCAAGGACATGTATTATACGACCCATGACGGCCGCCAGGTGCTGGACGGCACGGCCGGCC
TCTGGTGCGTCAATGCCGGCCACTGCCGCCCGAAGATCACCGAGGCAATCCGCGAGCAGGCCGGCGAGCTTGATTATGCC
CCGGCCTTCCAGCTCGGCCACCCCAAGGCCTTCGAACTGGCGAACCGCCTGGTGGACATTGCGCCGGAAGGCCTGAACCA
CGTTCTCTACACCAATTCCGGATCCGAATCCGTCGAGACTGCGCTCAAGGTGGCGCTCGCCTATCACCGCGTGAAGGGCA
ATGGTTCACGCTTCCGCCTGATCGGCCGCGAGCGCGGCTATCATGGCGTCAATTTCGGCGGCATCTCCGTCGGCGGCATC
GTCACCAACCGCAAGATGTTCGGCACGCTGCTGACCGGCGTCGATCACATGCCGCACACGCACCAGCCCGGCAAGAACAA
CTTCACCCGTGGCGAACCCGAGCATGGCGGCGACATTGCCACCGAGCTCGAGCGCATCGTCACCCTGCATGACGCCTCGA
CGGTCGCCGCCGTCATCGTCGAGCCGGTGGCCGGCTCCACCGGCGTTCTGATCCCACCGAAGGGCTATCTGCAGAAGCTG
CGCGAGATCTGCACCAAGCACGGCATCCTTCTGATCTTCGACGAGGTCATCACCGGTTTCGGCCGCCTCGGCGCCCCCTT
CGCCGCGCAATATTACGACGTCAAGCCTGACATGATCACCGCCGCCAAGGGACTGACCAATGGCGTCATTCCGATGGGCG
CCGTCTTCGTGACCTCCGAGATCCATGATGCCTTCATGAACGGCCCGGAGCACATGATCGAATTCTTCCACGGCTACACC
TATTCCGGCAATCCGATTGCCTCCGCTGCCGCGCTTGCCACGCTCGACACCTACAAGGAAGAGGGGCTGCTAACCCGCGC
CGCCGAGCTTTCCGACTACTGGGCCGACGCGCTGCATTCGCTGAAGGACTGTCCCAATGTCATCGACATCAGGAATACCG
GCCTGATCGGCGCGATCGAACTCGATCCGATCGCCGGGGAGCCGACCAAGCGCGCCTTCACCGCTTTCCTGAAAGCCTAT
GAAAGCGGCCTGCTGATCCGCACCACCGGCGATATCATCGCGCTGTCCCCGCCGCTGATCATCGAGAAGCAACATATCGA
CGAACTCTTCGGCAAGCTGCGGACCATCCTGCAGAACAACATCTGA

Upstream 100 bases:

>100_bases
TTTACCGTTGACGCTTCAAGAAGCCCTGATAATTTGACCGGGCAGTCAAAATATGGGCGTGTAGCCCCGGGAACGGGCCG
TCAGCGGCCAGGAGAACAGC

Downstream 100 bases:

>100_bases
AGACGCGTCCATAAGCGCTTCGGGCCCGCGGCGGACAAAATCCCCGCGGGTCTTTTCGTTTCGGAACAGAAAAACCTCAG
GTCACGGAGGCGACCGAAAG

Product: omega amino acid--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSNRLNAPNDLRAFWMPFTANRQFKQEPRMFVGAKDMYYTTHDGRQVLDGTAGLWCVNAGHCRPKITEAIREQAGELDYA
PAFQLGHPKAFELANRLVDIAPEGLNHVLYTNSGSESVETALKVALAYHRVKGNGSRFRLIGRERGYHGVNFGGISVGGI
VTNRKMFGTLLTGVDHMPHTHQPGKNNFTRGEPEHGGDIATELERIVTLHDASTVAAVIVEPVAGSTGVLIPPKGYLQKL
REICTKHGILLIFDEVITGFGRLGAPFAAQYYDVKPDMITAAKGLTNGVIPMGAVFVTSEIHDAFMNGPEHMIEFFHGYT
YSGNPIASAAALATLDTYKEEGLLTRAAELSDYWADALHSLKDCPNVIDIRNTGLIGAIELDPIAGEPTKRAFTAFLKAY
ESGLLIRTTGDIIALSPPLIIEKQHIDELFGKLRTILQNNI

Sequences:

>Translated_441_residues
MSNRLNAPNDLRAFWMPFTANRQFKQEPRMFVGAKDMYYTTHDGRQVLDGTAGLWCVNAGHCRPKITEAIREQAGELDYA
PAFQLGHPKAFELANRLVDIAPEGLNHVLYTNSGSESVETALKVALAYHRVKGNGSRFRLIGRERGYHGVNFGGISVGGI
VTNRKMFGTLLTGVDHMPHTHQPGKNNFTRGEPEHGGDIATELERIVTLHDASTVAAVIVEPVAGSTGVLIPPKGYLQKL
REICTKHGILLIFDEVITGFGRLGAPFAAQYYDVKPDMITAAKGLTNGVIPMGAVFVTSEIHDAFMNGPEHMIEFFHGYT
YSGNPIASAAALATLDTYKEEGLLTRAAELSDYWADALHSLKDCPNVIDIRNTGLIGAIELDPIAGEPTKRAFTAFLKAY
ESGLLIRTTGDIIALSPPLIIEKQHIDELFGKLRTILQNNI
>Mature_440_residues
SNRLNAPNDLRAFWMPFTANRQFKQEPRMFVGAKDMYYTTHDGRQVLDGTAGLWCVNAGHCRPKITEAIREQAGELDYAP
AFQLGHPKAFELANRLVDIAPEGLNHVLYTNSGSESVETALKVALAYHRVKGNGSRFRLIGRERGYHGVNFGGISVGGIV
TNRKMFGTLLTGVDHMPHTHQPGKNNFTRGEPEHGGDIATELERIVTLHDASTVAAVIVEPVAGSTGVLIPPKGYLQKLR
EICTKHGILLIFDEVITGFGRLGAPFAAQYYDVKPDMITAAKGLTNGVIPMGAVFVTSEIHDAFMNGPEHMIEFFHGYTY
SGNPIASAAALATLDTYKEEGLLTRAAELSDYWADALHSLKDCPNVIDIRNTGLIGAIELDPIAGEPTKRAFTAFLKAYE
SGLLIRTTGDIIALSPPLIIEKQHIDELFGKLRTILQNNI

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=401, Percent_Identity=31.9201995012469, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=28.4705882352941, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI284507298, Length=320, Percent_Identity=32.5, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=29.9303944315545, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=30.1790281329923, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI226442705, Length=427, Percent_Identity=29.2740046838407, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24119277, Length=443, Percent_Identity=26.86230248307, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI145693181, Length=343, Percent_Identity=34.402332361516, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786991, Length=435, Percent_Identity=31.0344827586207, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=30.8483290488432, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=30.4239401496259, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=28.0927835051546, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1787560, Length=410, Percent_Identity=31.219512195122, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786349, Length=347, Percent_Identity=28.2420749279539, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564660, Length=430, Percent_Identity=32.093023255814, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI25144271, Length=394, Percent_Identity=30.2030456852792, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=439, Percent_Identity=29.1571753986333, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=248, Percent_Identity=33.8709677419355, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=377, Percent_Identity=22.8116710875332, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=427, Percent_Identity=32.3185011709602, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324432, Length=407, Percent_Identity=30.7125307125307, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324386, Length=427, Percent_Identity=25.9953161592506, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=25.9345794392523, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=404, Percent_Identity=31.6831683168317, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI161085790, Length=435, Percent_Identity=30.1149425287356, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=30.7692307692308, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21356575, Length=437, Percent_Identity=28.8329519450801, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=22.3004694835681, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=22.3004694835681, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=22.3004694835681, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48236; Mature: 48105

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRLNAPNDLRAFWMPFTANRQFKQEPRMFVGAKDMYYTTHDGRQVLDGTAGLWCVNAG
CCCCCCCCCCCEEEEECCCCCCCHHHCCCEEECCCCEEEEECCCCCHHCCCCCEEEEECC
HCRPKITEAIREQAGELDYAPAFQLGHPKAFELANRLVDIAPEGLNHVLYTNSGSESVET
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
ALKVALAYHRVKGNGSRFRLIGRERGYHGVNFGGISVGGIVTNRKMFGTLLTGVDHMPHT
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEECCEEECHHHHHHHHHHCCCCCCC
HQPGKNNFTRGEPEHGGDIATELERIVTLHDASTVAAVIVEPVAGSTGVLIPPKGYLQKL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEHEEECCCCCCCEEECCHHHHHHH
REICTKHGILLIFDEVITGFGRLGAPFAAQYYDVKPDMITAAKGLTNGVIPMGAVFVTSE
HHHHHHCCEEEEEHHHHHHHHHCCCCHHHHEEECCCCHHHHHHCCCCCCCCCCCEEEHHH
IHDAFMNGPEHMIEFFHGYTYSGNPIASAAALATLDTYKEEGLLTRAAELSDYWADALHS
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LKDCPNVIDIRNTGLIGAIELDPIAGEPTKRAFTAFLKAYESGLLIRTTGDIIALSPPLI
HHCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEECCCCE
IEKQHIDELFGKLRTILQNNI
EEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNRLNAPNDLRAFWMPFTANRQFKQEPRMFVGAKDMYYTTHDGRQVLDGTAGLWCVNAG
CCCCCCCCCCEEEEECCCCCCCHHHCCCEEECCCCEEEEECCCCCHHCCCCCEEEEECC
HCRPKITEAIREQAGELDYAPAFQLGHPKAFELANRLVDIAPEGLNHVLYTNSGSESVET
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
ALKVALAYHRVKGNGSRFRLIGRERGYHGVNFGGISVGGIVTNRKMFGTLLTGVDHMPHT
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEECCEEECHHHHHHHHHHCCCCCCC
HQPGKNNFTRGEPEHGGDIATELERIVTLHDASTVAAVIVEPVAGSTGVLIPPKGYLQKL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEHEEECCCCCCCEEECCHHHHHHH
REICTKHGILLIFDEVITGFGRLGAPFAAQYYDVKPDMITAAKGLTNGVIPMGAVFVTSE
HHHHHHCCEEEEEHHHHHHHHHCCCCHHHHEEECCCCHHHHHHCCCCCCCCCCCEEEHHH
IHDAFMNGPEHMIEFFHGYTYSGNPIASAAALATLDTYKEEGLLTRAAELSDYWADALHS
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LKDCPNVIDIRNTGLIGAIELDPIAGEPTKRAFTAFLKAYESGLLIRTTGDIIALSPPLI
HHCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEECCCCE
IEKQHIDELFGKLRTILQNNI
EEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]