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The map label for this gene is str [H]

Identifier: 209550306

GI number: 209550306

Start: 2773752

End: 2774552

Strand: Direct

Name: str [H]

Synonym: Rleg2_2726

Alternate gene names: 209550306

Gene position: 2773752-2774552 (Clockwise)

Preceding gene: 209550305

Following gene: 209550308

Centisome position: 61.12

GC content: 64.42

Gene sequence:

>801_bases
ATGTTCGCTGCCCATCTTGATCGCTGGTCGCTGATATCGGACGGCGAGCCCATCATCACCCATTCAAGCCGACTGCTGCC
GGTCCTCTGGCAGGAGAAACCTGCCATGCTGAAAGTGGCCGTCGATGTCGACGAACGATACGGCGCGCTGTTGATGCAAT
GGTGGGATGGCGACGGCGCAGCCCATGTCTATGCTCATGAGGGCGACGCGGTGCTCCTGGAACGGGCGATGGGAGAACGC
TCGCTGCTTGCCATGGCGATGAACGGCGAGGACGACGAGGCAAGCCGCATCCTTTGCCGAACGGCGGCACGGCTGCATGC
GCCGCGCGAAAAACCGCTTCCCGATCCCATCCCCCTCACCCGCTGGTTCCGCGATCTCGAGCCGGCGGCAGGCAAACATG
GCGGCACGCTGGCCGAATGCTCGGCGATTGCCAATGCGCTGCTTGCCGATCCGCGTGACCTCACCGTCCTCCACGGCGAC
ATCCACCACGGCAATATCCTCGATTTCGAGGCGCGCGGCTGGCTGGCGATCGATCCGAAGCGGCTGCATGGCGAGCGCGG
CTTCGATTTCGCCAACATCTTCGCCAACGCGGAACTGCCTGTTAACACTGACCCCGCTCGTTTCCGCCGCCAGCTCGCCA
TCGTCTCGGCCGAAGCCGGGATCGAGCCGAAGCGGCTGCTACAATGGATCGCCGCCTATTCCGGCCTTTCCGCCGCCTGG
TTCCTCGGCGACCCGAACATAAAGCAGGCCGAGACCGCCTTGACGGTCGCCCGGATCGCGCTGGCCGAACTCGAGGCTTA
A

Upstream 100 bases:

>100_bases
CCCGCTCTCGAAAAGGTCGCCTGAACCTTTCGAATACACATTGCGAATCCCGCCTGAAGGCGGGATTTTCATTTCCCGCG
CATCTTTGTAGGGTGTGCCT

Downstream 100 bases:

>100_bases
CCTGCACTCTCGGACCAAGGTACGATCAAGGCCGCCGCCATGTCACGATGCGGTTCCGGCAGGCAGCCGAGTGCCACGAG
TGAGGCCCTCACCGCATCAT

Product: aminoglycoside/hydroxyurea antibiotic resistance kinase

Products: NA

Alternate protein names: Streptomycin 3''-phosphotransferase; SPH [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MFAAHLDRWSLISDGEPIITHSSRLLPVLWQEKPAMLKVAVDVDERYGALLMQWWDGDGAAHVYAHEGDAVLLERAMGER
SLLAMAMNGEDDEASRILCRTAARLHAPREKPLPDPIPLTRWFRDLEPAAGKHGGTLAECSAIANALLADPRDLTVLHGD
IHHGNILDFEARGWLAIDPKRLHGERGFDFANIFANAELPVNTDPARFRRQLAIVSAEAGIEPKRLLQWIAAYSGLSAAW
FLGDPNIKQAETALTVARIALAELEA

Sequences:

>Translated_266_residues
MFAAHLDRWSLISDGEPIITHSSRLLPVLWQEKPAMLKVAVDVDERYGALLMQWWDGDGAAHVYAHEGDAVLLERAMGER
SLLAMAMNGEDDEASRILCRTAARLHAPREKPLPDPIPLTRWFRDLEPAAGKHGGTLAECSAIANALLADPRDLTVLHGD
IHHGNILDFEARGWLAIDPKRLHGERGFDFANIFANAELPVNTDPARFRRQLAIVSAEAGIEPKRLLQWIAAYSGLSAAW
FLGDPNIKQAETALTVARIALAELEA
>Mature_266_residues
MFAAHLDRWSLISDGEPIITHSSRLLPVLWQEKPAMLKVAVDVDERYGALLMQWWDGDGAAHVYAHEGDAVLLERAMGER
SLLAMAMNGEDDEASRILCRTAARLHAPREKPLPDPIPLTRWFRDLEPAAGKHGGTLAECSAIANALLADPRDLTVLHGD
IHHGNILDFEARGWLAIDPKRLHGERGFDFANIFANAELPVNTDPARFRRQLAIVSAEAGIEPKRLLQWIAAYSGLSAAW
FLGDPNIKQAETALTVARIALAELEA

Specific function: The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation [H]

COG id: COG3570

COG function: function code V; Streptomycin 6-kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aminoglycoside phosphotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006748 [H]

Pfam domain/function: PF04655 APH_6_hur [H]

EC number: =2.7.1.87 [H]

Molecular weight: Translated: 29325; Mature: 29325

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAAHLDRWSLISDGEPIITHSSRLLPVLWQEKPAMLKVAVDVDERYGALLMQWWDGDGA
CCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEEECCCCE
AHVYAHEGDAVLLERAMGERSLLAMAMNGEDDEASRILCRTAARLHAPREKPLPDPIPLT
EEEEEECCCEEEHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHH
RWFRDLEPAAGKHGGTLAECSAIANALLADPRDLTVLHGDIHHGNILDFEARGWLAIDPK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCEEEECHH
RLHGERGFDFANIFANAELPVNTDPARFRRQLAIVSAEAGIEPKRLLQWIAAYSGLSAAW
HHCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCEEE
FLGDPNIKQAETALTVARIALAELEA
EECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFAAHLDRWSLISDGEPIITHSSRLLPVLWQEKPAMLKVAVDVDERYGALLMQWWDGDGA
CCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEEECCCCE
AHVYAHEGDAVLLERAMGERSLLAMAMNGEDDEASRILCRTAARLHAPREKPLPDPIPLT
EEEEEECCCEEEHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHH
RWFRDLEPAAGKHGGTLAECSAIANALLADPRDLTVLHGDIHHGNILDFEARGWLAIDPK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCEEEECHH
RLHGERGFDFANIFANAELPVNTDPARFRRQLAIVSAEAGIEPKRLLQWIAAYSGLSAAW
HHCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCEEE
FLGDPNIKQAETALTVARIALAELEA
EECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3889831 [H]