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The map label for this gene is trxB [H]

Identifier: 209550301

GI number: 209550301

Start: 2768509

End: 2769483

Strand: Direct

Name: trxB [H]

Synonym: Rleg2_2721

Alternate gene names: 209550301

Gene position: 2768509-2769483 (Clockwise)

Preceding gene: 209550299

Following gene: 209550302

Centisome position: 61.01

GC content: 62.67

Gene sequence:

>975_bases
ATGCCCGCCCGCCATACCAAGGTGCTCATCATCGGTTCCGGACCCGCAGGCTATACCGCCGCGGTCTATGCCGCGCGCGC
CATGCTGAAGCCGGTTTTGATCGCCGGTCTCGAACAGGGCGGCCAGCTGATGATCACCACCGATGTGGAGAATTATCCGG
GCTTTGCCGATCCCATCCAGGGCCCCTGGCTGATGGAACAGATGCTGCAGCAGGCAAAACATGTCGGCGCCGAGATCGTC
AACGATCTGGTGACCGAAGTCGACATGAACCAGCGCCCCTTCGTCGCCCGCACCGACAGCGGCCAGGTCTGGACTGCCGA
TACGCTGATCATCGCCACCGGCGCCAAGGCCAAGTGGCTCGGCATCGAGAGCGAGCAGCATTTCCAGGGCTTCGGCGTTT
CGGCCTGCGCCACCTGCGACGGTTTCTTCTATCGCAACAAGAATGTGATCGTGGTCGGCGGCGGCAACAGCGCCGTCGAG
GAGGCGCTCTACCTCTCCAACATCGCCAAGTCGGTGACATTGGTCCACCGCCGCGACTTCTTCCGGGCAGAAAAGATCCT
GCAGGAACGCTTGTTCTCCAAGGAGAACGTCAAGGTGTTGTGGAACACCGAAGTGGCCGAAATCACCGGCACGCCGGCCA
AGCCTCCGATGCCGCAATCCGTCTCCGGCGCACGACTGCGCGACGTCAAAACCGGCGCGATCACCGAGATGGCAATCGAT
GGCGTTTTCGTCGCCATCGGCCATGCGCCGGCAACCGAGCTCTTCAAGGACAAACTGAAGCTGAAGGACAACGGCTATCT
CTGGACGGCGCCGGACTCGACCGCGACCAGCCTGGAAGGGGTCTATGCCGCCGGCGACGTGACCGACGACACCTTCCGTC
AGGCAATCACTGCCGCCGGTCTTGGATGCATGGCAGCGCTTGAAGCCGAGCGCTATCTGACGGGTCACATGCCCGTCGCC
GTAGCCGCGGAGTAA

Upstream 100 bases:

>100_bases
TTGAATAAAAGCATTGGACGTTCATAAATGGCGCAGGGACCGCGAAACGGCCGTAATCGCCACTTAGCCGCCGCCCTCCT
GCCAGTCGAAAGGAAATGAC

Downstream 100 bases:

>100_bases
GATCGGCATGAGGGGTGGGGGAATGCCATTGGATTGGGATAAGCTGCGTATTTTTCACGCAGCTGCCGAAGCGGGTTCGT
TCACCCATGCGGCGGATAAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPARHTKVLIIGSGPAGYTAAVYAARAMLKPVLIAGLEQGGQLMITTDVENYPGFADPIQGPWLMEQMLQQAKHVGAEIV
NDLVTEVDMNQRPFVARTDSGQVWTADTLIIATGAKAKWLGIESEQHFQGFGVSACATCDGFFYRNKNVIVVGGGNSAVE
EALYLSNIAKSVTLVHRRDFFRAEKILQERLFSKENVKVLWNTEVAEITGTPAKPPMPQSVSGARLRDVKTGAITEMAID
GVFVAIGHAPATELFKDKLKLKDNGYLWTAPDSTATSLEGVYAAGDVTDDTFRQAITAAGLGCMAALEAERYLTGHMPVA
VAAE

Sequences:

>Translated_324_residues
MPARHTKVLIIGSGPAGYTAAVYAARAMLKPVLIAGLEQGGQLMITTDVENYPGFADPIQGPWLMEQMLQQAKHVGAEIV
NDLVTEVDMNQRPFVARTDSGQVWTADTLIIATGAKAKWLGIESEQHFQGFGVSACATCDGFFYRNKNVIVVGGGNSAVE
EALYLSNIAKSVTLVHRRDFFRAEKILQERLFSKENVKVLWNTEVAEITGTPAKPPMPQSVSGARLRDVKTGAITEMAID
GVFVAIGHAPATELFKDKLKLKDNGYLWTAPDSTATSLEGVYAAGDVTDDTFRQAITAAGLGCMAALEAERYLTGHMPVA
VAAE
>Mature_323_residues
PARHTKVLIIGSGPAGYTAAVYAARAMLKPVLIAGLEQGGQLMITTDVENYPGFADPIQGPWLMEQMLQQAKHVGAEIVN
DLVTEVDMNQRPFVARTDSGQVWTADTLIIATGAKAKWLGIESEQHFQGFGVSACATCDGFFYRNKNVIVVGGGNSAVEE
ALYLSNIAKSVTLVHRRDFFRAEKILQERLFSKENVKVLWNTEVAEITGTPAKPPMPQSVSGARLRDVKTGAITEMAIDG
VFVAIGHAPATELFKDKLKLKDNGYLWTAPDSTATSLEGVYAAGDVTDDTFRQAITAAGLGCMAALEAERYLTGHMPVAV
AAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=55.625, Blast_Score=342, Evalue=1e-95,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=34.6031746031746, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=42.5465838509317, Blast_Score=266, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=42.5, Blast_Score=265, Evalue=1e-71,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34847; Mature: 34716

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARHTKVLIIGSGPAGYTAAVYAARAMLKPVLIAGLEQGGQLMITTDVENYPGFADPIQ
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWLMEQMLQQAKHVGAEIVNDLVTEVDMNQRPFVARTDSGQVWTADTLIIATGAKAKWL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECEEEEEECCCEEEE
GIESEQHFQGFGVSACATCDGFFYRNKNVIVVGGGNSAVEEALYLSNIAKSVTLVHRRDF
ECCCHHHHCCCCCHHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FRAEKILQERLFSKENVKVLWNTEVAEITGTPAKPPMPQSVSGARLRDVKTGAITEMAID
HHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHC
GVFVAIGHAPATELFKDKLKLKDNGYLWTAPDSTATSLEGVYAAGDVTDDTFRQAITAAG
EEEEEECCCCHHHHHHHHHEECCCCEEEECCCCCCHHCCCEEEECCCCHHHHHHHHHHHC
LGCMAALEAERYLTGHMPVAVAAE
HHHHHHHHHHHHEECCCCEEEECC
>Mature Secondary Structure 
PARHTKVLIIGSGPAGYTAAVYAARAMLKPVLIAGLEQGGQLMITTDVENYPGFADPIQ
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWLMEQMLQQAKHVGAEIVNDLVTEVDMNQRPFVARTDSGQVWTADTLIIATGAKAKWL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECEEEEEECCCEEEE
GIESEQHFQGFGVSACATCDGFFYRNKNVIVVGGGNSAVEEALYLSNIAKSVTLVHRRDF
ECCCHHHHCCCCCHHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FRAEKILQERLFSKENVKVLWNTEVAEITGTPAKPPMPQSVSGARLRDVKTGAITEMAID
HHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHC
GVFVAIGHAPATELFKDKLKLKDNGYLWTAPDSTATSLEGVYAAGDVTDDTFRQAITAAG
EEEEEECCCCHHHHHHHHHEECCCCEEEECCCCCCHHCCCEEEECCCCHHHHHHHHHHHC
LGCMAALEAERYLTGHMPVAVAAE
HHHHHHHHHHHHEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]