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The map label for this gene is RecD [H]

Identifier: 20806994

GI number: 20806994

Start: 501695

End: 503992

Strand: Direct

Name: RecD [H]

Synonym: TTE0489

Alternate gene names: 20806994

Gene position: 501695-503992 (Clockwise)

Preceding gene: 20806993

Following gene: 20806995

Centisome position: 18.65

GC content: 39.73

Gene sequence:

>2298_bases
TTGACAAAAATAAAAGGCCTAAACCCTTTATATCCTCCTCTAAATAGGTTAAAATTAAGTTGTAAAATATCTTTAACGGG
TGGAAAAGCCATGGTAGAAATAGAGGGTGTAGTAGAAGAGATAATCTTTAGAAACGAGCAAAACGGGTATACGGTTCTGG
AATTGGATATTGAAGGGGATATGGTGACTGCTGTAGGTGTAATGCCCTTTGTTACGGTGGGAGAGAGAATAAAGGTGCAG
GGGGAATGGGTAGTCCATCCTGATTACGGAGACCAGATACGAGTTATCAATTACCAGACTCTTTCTCCCAATACCCTGGA
AGGGATAGAGCGCTTTTTAGCATCAGGCCTGATACCTGGGATTGGCCCTGTCACCGCGAGAAAGATTGTAGAAAGATTTG
GGCTTGACTCTCTTCATGTTATAGAGACAGAGCCTCACAGGTTGAGGGAGATAAAAGGTTTAAGCGATGAGAAGATAAAG
AGAATAAGTGAAGCTTATGAGATGCAGAAGGGAATAAAAGAAGTAATGGTGTTTCTACATCAATTCGGGATTTCTAGCCA
TATGGCTATAAAAATATACAAAGAATACGGGAATAATGCAATAGAAATCATCAAGCAAAATCCTTACAGACTTGCTGATG
ACATATTCGGCATAGGATTTAAGACTGCTGACAAAATTGCGGAGAGCTTGGGCATTGACCCGCATTCCACATACCGCATT
TCTGCAGGGGCAAGGTATGTTTTAATGCAGTACGCTGCAAATGGGCACACCTATGTGCCAAAAGAACTCTTAAAAAAAGA
AACTGCCCAGCTCCTCGAGGTAAGCGAAGAAGAAGTGGAGGATGCTTTTGTGCTTTTAGCTCAAAATGAAAAAATACACA
TAGAAAGGTTTGAGGACGAAACAGTAGGGGTTTATTACATCCCCTATTATGTGGCAGAACTTCATACTGCAGAAAGGCTT
TTTACAATGACAGTGACCCAGTGCGAAGACCTCAAAATAGACGTGCAAAAAGAAATAAGGGATTTTGAAAAAGAAGCAGG
AATAGTTTTAGAGAAAACTCAAAAATTGGCGGTAGAAGAAGCCATAAAGAATTCGGTCGTGGTCATAACAGGAGGACCTG
GCACGGGTAAGACTACGATTATAAACTGTATAATAAGGATTTTTGAAAAAGCCAATAAAAAAGTGGCCCTTGCTGCTCCT
ACAGGAAGAGCGGCAAAGAGGATAACTGAAGCAACGGGAAAAGAGGCAAAGACCATTCACAGGCTTTTAGAGTATACCTA
TACGGAAGAGGAAGGGAAAGGGTTTAATAAAAACGAAAAAGATCCTTTAAAATACGATGTAATCATAATAGATGAAGCTT
CTATGGTGGATATTTTGCTTATGAATGCTCTTTTAAAGGCTATTCCTGCCGGATCAAGGCTTATTCTTGTGGGAGATGCT
GACCAGCTCCCATCTGTTGGAGCGGGAAATGTTTTAAGAGACATAATAGACAGTGGAATTGTAAAAGTGATACGGCTAAA
AGAAATATTCAGGCAGCAGAAAGAGAGCCTTATTGTAGTAAATGCCCACAAGATAAATAACGGCGAATATCCTACCTACA
ATGACAAAAATGGAGACTTCTTCTTTTTAAGCGTAGCTACACAGGAAGACATGCTAAAGACAATACTAGACCTTGTGACT
AATAGGCTTCCTAAAGCTTATGGCTTTCATCCGGTTAACGATATTCAGGTCCTTACTCCCATGAAAAAGGGAATAATAGG
AGTGCACAATTTAAATATAGAACTTCAGAAGGTCTTAAACCCTCCTTCTAAAGACAAAGCAGAAAAACCAATGAAAGAAT
TTACTTTTAGAGTCGGTGATAAAGTGATGCAGATCAAGAACAACTATAGAATGACCTGGAAAAGAGGGCATGAGGAAGGA
GAAGGAGTTTTCAACGGTGACATAGGGATAATCCAGTCAATAGATGAGGAACTTCAAGAAGTTACCGTGTATTTTGACGA
CGAAAAAGTAGTGACTTACGATTTTTCCGATTTGGACGAACTTACCTTATCTTACGCTATCACAGTTCACAAGAGTCAGG
GCAGCGAATTTCCTGTGGTGATAATGCCAGTGACATACGGACCTCCTATGCTTTTAACCCGCAATCTTCTTTACACAGCT
GTTACAAGGGCAAAAAAGCTGGTGGTTTTAGTAGGGCAGGAGAAATATTTAAAATTTATGATTGACAACAACAGGATTTC
TAAAAGATATTCAGGACTTCTTTCCAGGCTAAAAAAGACCTTGATTTACATCCAATAA

Upstream 100 bases:

>100_bases
AAAGCCCGGGTTTTGCCCGGGCTTGTGGCGTTTTTTATATATTTTTTGTAACGCCAGAGATTTTTAAAACCGCTCCGCTA
AAATATATTATACATTAGTT

Downstream 100 bases:

>100_bases
TTTATAGAAAAGTGTAAATTTTAATTTATTTGTGCCGATAACATAATTGAAAGAAGAAAGCGATGAGGGATGTATAAATG
ACTTTTTTGGACCTGCTTTT

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 764

Protein sequence:

>765_residues
MTKIKGLNPLYPPLNRLKLSCKISLTGGKAMVEIEGVVEEIIFRNEQNGYTVLELDIEGDMVTAVGVMPFVTVGERIKVQ
GEWVVHPDYGDQIRVINYQTLSPNTLEGIERFLASGLIPGIGPVTARKIVERFGLDSLHVIETEPHRLREIKGLSDEKIK
RISEAYEMQKGIKEVMVFLHQFGISSHMAIKIYKEYGNNAIEIIKQNPYRLADDIFGIGFKTADKIAESLGIDPHSTYRI
SAGARYVLMQYAANGHTYVPKELLKKETAQLLEVSEEEVEDAFVLLAQNEKIHIERFEDETVGVYYIPYYVAELHTAERL
FTMTVTQCEDLKIDVQKEIRDFEKEAGIVLEKTQKLAVEEAIKNSVVVITGGPGTGKTTIINCIIRIFEKANKKVALAAP
TGRAAKRITEATGKEAKTIHRLLEYTYTEEEGKGFNKNEKDPLKYDVIIIDEASMVDILLMNALLKAIPAGSRLILVGDA
DQLPSVGAGNVLRDIIDSGIVKVIRLKEIFRQQKESLIVVNAHKINNGEYPTYNDKNGDFFFLSVATQEDMLKTILDLVT
NRLPKAYGFHPVNDIQVLTPMKKGIIGVHNLNIELQKVLNPPSKDKAEKPMKEFTFRVGDKVMQIKNNYRMTWKRGHEEG
EGVFNGDIGIIQSIDEELQEVTVYFDDEKVVTYDFSDLDELTLSYAITVHKSQGSEFPVVIMPVTYGPPMLLTRNLLYTA
VTRAKKLVVLVGQEKYLKFMIDNNRISKRYSGLLSRLKKTLIYIQ

Sequences:

>Translated_765_residues
MTKIKGLNPLYPPLNRLKLSCKISLTGGKAMVEIEGVVEEIIFRNEQNGYTVLELDIEGDMVTAVGVMPFVTVGERIKVQ
GEWVVHPDYGDQIRVINYQTLSPNTLEGIERFLASGLIPGIGPVTARKIVERFGLDSLHVIETEPHRLREIKGLSDEKIK
RISEAYEMQKGIKEVMVFLHQFGISSHMAIKIYKEYGNNAIEIIKQNPYRLADDIFGIGFKTADKIAESLGIDPHSTYRI
SAGARYVLMQYAANGHTYVPKELLKKETAQLLEVSEEEVEDAFVLLAQNEKIHIERFEDETVGVYYIPYYVAELHTAERL
FTMTVTQCEDLKIDVQKEIRDFEKEAGIVLEKTQKLAVEEAIKNSVVVITGGPGTGKTTIINCIIRIFEKANKKVALAAP
TGRAAKRITEATGKEAKTIHRLLEYTYTEEEGKGFNKNEKDPLKYDVIIIDEASMVDILLMNALLKAIPAGSRLILVGDA
DQLPSVGAGNVLRDIIDSGIVKVIRLKEIFRQQKESLIVVNAHKINNGEYPTYNDKNGDFFFLSVATQEDMLKTILDLVT
NRLPKAYGFHPVNDIQVLTPMKKGIIGVHNLNIELQKVLNPPSKDKAEKPMKEFTFRVGDKVMQIKNNYRMTWKRGHEEG
EGVFNGDIGIIQSIDEELQEVTVYFDDEKVVTYDFSDLDELTLSYAITVHKSQGSEFPVVIMPVTYGPPMLLTRNLLYTA
VTRAKKLVVLVGQEKYLKFMIDNNRISKRYSGLLSRLKKTLIYIQ
>Mature_764_residues
TKIKGLNPLYPPLNRLKLSCKISLTGGKAMVEIEGVVEEIIFRNEQNGYTVLELDIEGDMVTAVGVMPFVTVGERIKVQG
EWVVHPDYGDQIRVINYQTLSPNTLEGIERFLASGLIPGIGPVTARKIVERFGLDSLHVIETEPHRLREIKGLSDEKIKR
ISEAYEMQKGIKEVMVFLHQFGISSHMAIKIYKEYGNNAIEIIKQNPYRLADDIFGIGFKTADKIAESLGIDPHSTYRIS
AGARYVLMQYAANGHTYVPKELLKKETAQLLEVSEEEVEDAFVLLAQNEKIHIERFEDETVGVYYIPYYVAELHTAERLF
TMTVTQCEDLKIDVQKEIRDFEKEAGIVLEKTQKLAVEEAIKNSVVVITGGPGTGKTTIINCIIRIFEKANKKVALAAPT
GRAAKRITEATGKEAKTIHRLLEYTYTEEEGKGFNKNEKDPLKYDVIIIDEASMVDILLMNALLKAIPAGSRLILVGDAD
QLPSVGAGNVLRDIIDSGIVKVIRLKEIFRQQKESLIVVNAHKINNGEYPTYNDKNGDFFFLSVATQEDMLKTILDLVTN
RLPKAYGFHPVNDIQVLTPMKKGIIGVHNLNIELQKVLNPPSKDKAEKPMKEFTFRVGDKVMQIKNNYRMTWKRGHEEGE
GVFNGDIGIIQSIDEELQEVTVYFDDEKVVTYDFSDLDELTLSYAITVHKSQGSEFPVVIMPVTYGPPMLLTRNLLYTAV
TRAKKLVVLVGQEKYLKFMIDNNRISKRYSGLLSRLKKTLIYIQ

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789182, Length=470, Percent_Identity=29.5744680851064, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5

Molecular weight: Translated: 86299; Mature: 86168

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIKGLNPLYPPLNRLKLSCKISLTGGKAMVEIEGVVEEIIFRNEQNGYTVLELDIEGD
CCCCCCCCCCCCCHHHEEEEEEEEEECCCEEEEHHHHHHHHHHCCCCCCEEEEEEEECCC
MVTAVGVMPFVTVGERIKVQGEWVVHPDYGDQIRVINYQTLSPNTLEGIERFLASGLIPG
EEEHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCC
IGPVTARKIVERFGLDSLHVIETEPHRLREIKGLSDEKIKRISEAYEMQKGIKEVMVFLH
CCHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QFGISSHMAIKIYKEYGNNAIEIIKQNPYRLADDIFGIGFKTADKIAESLGIDPHSTYRI
HHCCCCCEEEEEEHHHCCCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEE
SAGARYVLMQYAANGHTYVPKELLKKETAQLLEVSEEEVEDAFVLLAQNEKIHIERFEDE
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEEEECCCEEEEEEECCC
TVGVYYIPYYVAELHTAERLFTMTVTQCEDLKIDVQKEIRDFEKEAGIVLEKTQKLAVEE
CEEEEEHHHHHHHHHHHHHEEEEEEECCCCCEEEHHHHHHHHHHHCCEEEEHHHHHHHHH
AIKNSVVVITGGPGTGKTTIINCIIRIFEKANKKVALAAPTGRAAKRITEATGKEAKTIH
HHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHH
RLLEYTYTEEEGKGFNKNEKDPLKYDVIIIDEASMVDILLMNALLKAIPAGSRLILVGDA
HHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECC
DQLPSVGAGNVLRDIIDSGIVKVIRLKEIFRQQKESLIVVNAHKINNGEYPTYNDKNGDF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCE
FFLSVATQEDMLKTILDLVTNRLPKAYGFHPVNDIQVLTPMKKGIIGVHNLNIELQKVLN
EEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHCEEEEEECCEEEHHHCC
PPSKDKAEKPMKEFTFRVGDKVMQIKNNYRMTWKRGHEEGEGVFNGDIGIIQSIDEELQE
CCCCCHHHCCHHHHHHHHCHHHHHHHCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHE
VTVYFDDEKVVTYDFSDLDELTLSYAITVHKSQGSEFPVVIMPVTYGPPMLLTRNLLYTA
EEEEECCCEEEEECCCCHHHEEEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHH
VTRAKKLVVLVGQEKYLKFMIDNNRISKRYSGLLSRLKKTLIYIQ
HHHCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
TKIKGLNPLYPPLNRLKLSCKISLTGGKAMVEIEGVVEEIIFRNEQNGYTVLELDIEGD
CCCCCCCCCCCCHHHEEEEEEEEEECCCEEEEHHHHHHHHHHCCCCCCEEEEEEEECCC
MVTAVGVMPFVTVGERIKVQGEWVVHPDYGDQIRVINYQTLSPNTLEGIERFLASGLIPG
EEEHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCC
IGPVTARKIVERFGLDSLHVIETEPHRLREIKGLSDEKIKRISEAYEMQKGIKEVMVFLH
CCHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QFGISSHMAIKIYKEYGNNAIEIIKQNPYRLADDIFGIGFKTADKIAESLGIDPHSTYRI
HHCCCCCEEEEEEHHHCCCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEE
SAGARYVLMQYAANGHTYVPKELLKKETAQLLEVSEEEVEDAFVLLAQNEKIHIERFEDE
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEEEECCCEEEEEEECCC
TVGVYYIPYYVAELHTAERLFTMTVTQCEDLKIDVQKEIRDFEKEAGIVLEKTQKLAVEE
CEEEEEHHHHHHHHHHHHHEEEEEEECCCCCEEEHHHHHHHHHHHCCEEEEHHHHHHHHH
AIKNSVVVITGGPGTGKTTIINCIIRIFEKANKKVALAAPTGRAAKRITEATGKEAKTIH
HHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHH
RLLEYTYTEEEGKGFNKNEKDPLKYDVIIIDEASMVDILLMNALLKAIPAGSRLILVGDA
HHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECC
DQLPSVGAGNVLRDIIDSGIVKVIRLKEIFRQQKESLIVVNAHKINNGEYPTYNDKNGDF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCE
FFLSVATQEDMLKTILDLVTNRLPKAYGFHPVNDIQVLTPMKKGIIGVHNLNIELQKVLN
EEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHCEEEEEECCEEEHHHCC
PPSKDKAEKPMKEFTFRVGDKVMQIKNNYRMTWKRGHEEGEGVFNGDIGIIQSIDEELQE
CCCCCHHHCCHHHHHHHHCHHHHHHHCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHE
VTVYFDDEKVVTYDFSDLDELTLSYAITVHKSQGSEFPVVIMPVTYGPPMLLTRNLLYTA
EEEEECCCEEEEECCCCHHHEEEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHH
VTRAKKLVVLVGQEKYLKFMIDNNRISKRYSGLLSRLKKTLIYIQ
HHHCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]