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The map label for this gene is ComFC [H]

Identifier: 20806995

GI number: 20806995

Start: 504070

End: 504756

Strand: Direct

Name: ComFC [H]

Synonym: TTE0490

Alternate gene names: 20806995

Gene position: 504070-504756 (Clockwise)

Preceding gene: 20806994

Following gene: 20806996

Centisome position: 18.74

GC content: 39.16

Gene sequence:

>687_bases
ATGACTTTTTTGGACCTGCTTTTTCCTCCCAAGACCAGTTGCATTGTTTGCAATGCCTCTATAAAAAGTGGATACTTGTG
CGATAGGTGTAAGGCATCTCTTGAAATTATCAATGGCAAAAGGTGCAGAATATGCGGCAAGCCCCTTAAAGAAGGAGAAA
TATGCAGTGATTGCCTCAAAACACCGCATTATTTTAAACAAAATGTAAGTCCATTTGAATATGAGGGCGTGGTAAAAGAA
CTCATAGGAAAATTTAAATATTTCAATGAAAGGCACTTAGCTTCATTTTTCGCCGATTACATGGCTGATGCAGTAAAAAA
TATGGGCTGGAATATTGAAGTCATAGTTCCCGTTCCACTTCACAGGATAAGACTTGATGAAAGAGGATACAATCAGTCTG
AACTTCTGGCAAGGGAGCTTTCTTACAGGCTCAATATCTTCATGTCAAAAGCTCTAAGGCGGGTTAAGAATACCACAACT
CAGACTGCTCTTCACAGAGAGGAAAGGATGGAAAATGTAAAAGGGGCTTTTAAAGTTACATATAAAGATACAATTGAAGG
GAAAAATGTTCTTTTAGTGGACGATGTTTTGACAACAGGGGCAACCCTTGACGAATGTGCGAAAGCATTGAAGGAAAATG
GGGCAAAAGAAGTTTATGTTGTCACTATTGCAACTGGCAGGATGTGA

Upstream 100 bases:

>100_bases
AGACCTTGATTTACATCCAATAATTTATAGAAAAGTGTAAATTTTAATTTATTTGTGCCGATAACATAATTGAAAGAAGA
AAGCGATGAGGGATGTATAA

Downstream 100 bases:

>100_bases
TGGGGATTATATAAAAGGGGATGAAAATTATGGAAATAAGGAATTGCAAGCGGTGTGGAAGGCCTTATATCTATACGGGA
AAAGATTTATGCCCTGTGTG

Product: amidophosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTFLDLLFPPKTSCIVCNASIKSGYLCDRCKASLEIINGKRCRICGKPLKEGEICSDCLKTPHYFKQNVSPFEYEGVVKE
LIGKFKYFNERHLASFFADYMADAVKNMGWNIEVIVPVPLHRIRLDERGYNQSELLARELSYRLNIFMSKALRRVKNTTT
QTALHREERMENVKGAFKVTYKDTIEGKNVLLVDDVLTTGATLDECAKALKENGAKEVYVVTIATGRM

Sequences:

>Translated_228_residues
MTFLDLLFPPKTSCIVCNASIKSGYLCDRCKASLEIINGKRCRICGKPLKEGEICSDCLKTPHYFKQNVSPFEYEGVVKE
LIGKFKYFNERHLASFFADYMADAVKNMGWNIEVIVPVPLHRIRLDERGYNQSELLARELSYRLNIFMSKALRRVKNTTT
QTALHREERMENVKGAFKVTYKDTIEGKNVLLVDDVLTTGATLDECAKALKENGAKEVYVVTIATGRM
>Mature_227_residues
TFLDLLFPPKTSCIVCNASIKSGYLCDRCKASLEIINGKRCRICGKPLKEGEICSDCLKTPHYFKQNVSPFEYEGVVKEL
IGKFKYFNERHLASFFADYMADAVKNMGWNIEVIVPVPLHRIRLDERGYNQSELLARELSYRLNIFMSKALRRVKNTTTQ
TALHREERMENVKGAFKVTYKDTIEGKNVLLVDDVLTTGATLDECAKALKENGAKEVYVVTIATGRM

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=216, Percent_Identity=31.0185185185185, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 25935; Mature: 25804

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLDLLFPPKTSCIVCNASIKSGYLCDRCKASLEIINGKRCRICGKPLKEGEICSDCLK
CCCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHC
TPHYFKQNVSPFEYEGVVKELIGKFKYFNERHLASFFADYMADAVKNMGWNIEVIVPVPL
CCHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCH
HRIRLDERGYNQSELLARELSYRLNIFMSKALRRVKNTTTQTALHREERMENVKGAFKVT
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
YKDTIEGKNVLLVDDVLTTGATLDECAKALKENGAKEVYVVTIATGRM
EECCCCCCCEEEEECHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCC
>Mature Secondary Structure 
TFLDLLFPPKTSCIVCNASIKSGYLCDRCKASLEIINGKRCRICGKPLKEGEICSDCLK
CCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHC
TPHYFKQNVSPFEYEGVVKELIGKFKYFNERHLASFFADYMADAVKNMGWNIEVIVPVPL
CCHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCH
HRIRLDERGYNQSELLARELSYRLNIFMSKALRRVKNTTTQTALHREERMENVKGAFKVT
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
YKDTIEGKNVLLVDDVLTTGATLDECAKALKENGAKEVYVVTIATGRM
EECCCCCCCEEEEECHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]