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The map label for this gene is 20806959

Identifier: 20806959

GI number: 20806959

Start: 466027

End: 466923

Strand: Direct

Name: 20806959

Synonym: TTE0450

Alternate gene names: NA

Gene position: 466027-466923 (Clockwise)

Preceding gene: 20806958

Following gene: 20806960

Centisome position: 17.33

GC content: 37.24

Gene sequence:

>897_bases
ATGAATCAGATAATTGAATGTGTGCCCAATGTGAGCGAAGGAAGGGATCAGGAAAAGATTTCTGAGCTCATAAAAGAAGT
GGTTTCAACAGAAGGAGTAAAACTTTTGGACTATTCTTCAGATAAAGACCACAATAGGACAGTTATAACCTTTGTTGGAG
ATAAAGAGGGGGTAAAAGAAGCGGCTTTTAAGCTCATAAAAAAAGCTTCAGAGATAATTGACATGAGATATCACAAAGGA
GAACACCCTAGAATTGGAGCTGTGGATGTGGTTCCTTTTGTTCCTGTAAAAAATGTTACAATGGAAGAATGCGTACAGAT
TGCAAGGGAACTAGGAGAAAGAGTAGGGAAAGAGCTTAATATACCTGTTTATCTGTATGAAGAAGCAGCTACAACTCCTG
AGAGAAAAAATTTAGAGAATATAAGGCGAGGGGAATATGAAGGCTTTTTTGAAAAGATAAAACAGCCAGAGTGGAAGCCC
GATTTTGGACCTTCTGAGATGAATCCTAAAAGCGGTGCAATAGTAATTGGGGCAAGAAATTTTTTGATTGCCTTCAATGT
AAACCTTGGCACAAATGATATTGAAATAGCTAATAAAATCGCTAAAGCTGTCAGATTTTCAAGTGGTGGCTATAGATATG
TGAAGGCAATGGGGGTTGAATTAAGAGAAAGAGGGATTGTGCAGGTTTCAATGAACCTTACAGATTTTAACAAGACACCG
ATTTACAGAGTTTTTGAGACAATTAAAGCAGAAGCTTCAAGGTATGGTGTGAATGTAGTAGGAAGTGAAATAATAGGCCT
TGTGCCTTCAAAAGCGTTGCTAGATGTTGCCGATTATTATTTGAGATTAGAAAATTTCTCCATGGATATGGTTTTGGAAA
ACAGAATTTACGAATGA

Upstream 100 bases:

>100_bases
GACACGCCGATGCAGGATATGAAATAGCAATTAAGACTGCAAAAGAAAAGGGAATAAAAATGCCTATGCTTAAATGAATT
TGAAAGGGCGTGGGAGAAAG

Downstream 100 bases:

>100_bases
GGTGTTCATATGAGAGCAGATTTATTAATATACAATATAAGTAAAATTTATACGCCGATTGGGACGAAACCTCTTTGTGG
AGAAGATATGGAAAAAATAG

Product: glutamate formiminotransferase

Products: tetrahydrofolate; N-formimidoyl-L-glutamate

Alternate protein names: Glutamate Formimidoyltransferase; Formimidoyltransferase-Cyclodeaminase; Formiminotransferase-Cyclodeaminase; Formiminotransferase-Cyclodeaminase-Related Protein; Formiminotransferase; Formiminotransferase Domain Protein; Formimidoyltetrahydrofolate Cyclodeaminase; Formiminotransferase-Like

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNQIIECVPNVSEGRDQEKISELIKEVVSTEGVKLLDYSSDKDHNRTVITFVGDKEGVKEAAFKLIKKASEIIDMRYHKG
EHPRIGAVDVVPFVPVKNVTMEECVQIARELGERVGKELNIPVYLYEEAATTPERKNLENIRRGEYEGFFEKIKQPEWKP
DFGPSEMNPKSGAIVIGARNFLIAFNVNLGTNDIEIANKIAKAVRFSSGGYRYVKAMGVELRERGIVQVSMNLTDFNKTP
IYRVFETIKAEASRYGVNVVGSEIIGLVPSKALLDVADYYLRLENFSMDMVLENRIYE

Sequences:

>Translated_298_residues
MNQIIECVPNVSEGRDQEKISELIKEVVSTEGVKLLDYSSDKDHNRTVITFVGDKEGVKEAAFKLIKKASEIIDMRYHKG
EHPRIGAVDVVPFVPVKNVTMEECVQIARELGERVGKELNIPVYLYEEAATTPERKNLENIRRGEYEGFFEKIKQPEWKP
DFGPSEMNPKSGAIVIGARNFLIAFNVNLGTNDIEIANKIAKAVRFSSGGYRYVKAMGVELRERGIVQVSMNLTDFNKTP
IYRVFETIKAEASRYGVNVVGSEIIGLVPSKALLDVADYYLRLENFSMDMVLENRIYE
>Mature_298_residues
MNQIIECVPNVSEGRDQEKISELIKEVVSTEGVKLLDYSSDKDHNRTVITFVGDKEGVKEAAFKLIKKASEIIDMRYHKG
EHPRIGAVDVVPFVPVKNVTMEECVQIARELGERVGKELNIPVYLYEEAATTPERKNLENIRRGEYEGFFEKIKQPEWKP
DFGPSEMNPKSGAIVIGARNFLIAFNVNLGTNDIEIANKIAKAVRFSSGGYRYVKAMGVELRERGIVQVSMNLTDFNKTP
IYRVFETIKAEASRYGVNVVGSEIIGLVPSKALLDVADYYLRLENFSMDMVLENRIYE

Specific function: Unknown

COG id: COG3643

COG function: function code E; Glutamate formiminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI46255035, Length=293, Percent_Identity=47.098976109215, Blast_Score=271, Evalue=6e-73,
Organism=Homo sapiens, GI11140815, Length=293, Percent_Identity=47.098976109215, Blast_Score=271, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.2.5

Molecular weight: Translated: 33706; Mature: 33706

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIIECVPNVSEGRDQEKISELIKEVVSTEGVKLLDYSSDKDHNRTVITFVGDKEGVKE
CCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCHHH
AAFKLIKKASEIIDMRYHKGEHPRIGAVDVVPFVPVKNVTMEECVQIARELGERVGKELN
HHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
IPVYLYEEAATTPERKNLENIRRGEYEGFFEKIKQPEWKPDFGPSEMNPKSGAIVIGARN
CCEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECE
FLIAFNVNLGTNDIEIANKIAKAVRFSSGGYRYVKAMGVELRERGIVQVSMNLTDFNKTP
EEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEEEEECCCCCCH
IYRVFETIKAEASRYGVNVVGSEIIGLVPSKALLDVADYYLRLENFSMDMVLENRIYE
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MNQIIECVPNVSEGRDQEKISELIKEVVSTEGVKLLDYSSDKDHNRTVITFVGDKEGVKE
CCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCHHH
AAFKLIKKASEIIDMRYHKGEHPRIGAVDVVPFVPVKNVTMEECVQIARELGERVGKELN
HHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
IPVYLYEEAATTPERKNLENIRRGEYEGFFEKIKQPEWKPDFGPSEMNPKSGAIVIGARN
CCEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECE
FLIAFNVNLGTNDIEIANKIAKAVRFSSGGYRYVKAMGVELRERGIVQVSMNLTDFNKTP
EEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEEEEECCCCCCH
IYRVFETIKAEASRYGVNVVGSEIIGLVPSKALLDVADYYLRLENFSMDMVLENRIYE
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-formimidoyltetrahydrofolate; L-glutamate

Specific reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA