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The map label for this gene is mtlR [H]

Identifier: 20806857

GI number: 20806857

Start: 360635

End: 362656

Strand: Direct

Name: mtlR [H]

Synonym: TTE0340

Alternate gene names: 20806857

Gene position: 360635-362656 (Clockwise)

Preceding gene: 20806856

Following gene: 20806858

Centisome position: 13.41

GC content: 36.5

Gene sequence:

>2022_bases
ATGGAAGATTTGAGTGTAAGGCAGAAGTTTATCCTTAAAAATTTAATAGAAAAGGGACCATTTGAAATAGCTGACCTTGC
CAATCTTATGGATGTCAGTGAAAGAACGGTTTTAAGAGAAGTGGCATTAATAAACGAACGCTTAAGGGATTTTAATGTAA
AAATTGTAGAACAGGGGAGAAAGATATTCATAGAAGGAGAGGAAGAGGCGCTCAAGAGGGTTTACAGTTCTTTGGGCGCC
ATTCCTCTCCAATGGCTTTTAACACCTGACCAAAGGCAGGTTTTGATGACTCTTCAGCTTCTTCTTTCTGATGAACCCAT
TAAAGCTGGCTATTTCAGCTATCAGTTTAATGTGGTTGAAGGCACAATAAGCCTTTACCTCGATAAAATTGAAGAGTGGC
TTAGGATGAGAAAGCTCACGCTTATAAGAAGAAGAGGATATGGGATAAAAGTAGAGGGCAGTGAAGTTGATAGAAGAAAT
GCCATTATAGAGCTATTTTACAATTATACGCCAATGGAAGACCTGCTGCAATTTATTTACGATGAAGAAAAAGGCAAATA
CTTCAAAGCCTTTTTTGATTCAGTGTTTGGCAAGGATTTGGTAGAGAAAGTAAAAAGTCTGTGCGAAAAAATTAAAGAAG
CCGTATACGAAGAACTGCCTGATTTAAATTATTTTGGCATGTTTGTTCATATACTTCTTTCAATCTACAGAAGCAAAGAA
GGAAAGGCCATTGAACTTGATAGAGAATTTATAAATGATATATTACAGTCAGAAGAGTTCAATTTTATGAAGAAAGTTGA
AAAAATCCTTGAAGAGGAAGATTTCTACCTGCCAGAGTCAGAAATAGCATATTTAGCTATTCACTTGAGCCCAAAAAAGT
ATGTGTACAAACAGCATAGGTTTGAAGAATTGGGCATTACTCTGGAGGAGCTGTCAAAAGAGGTCGTAGAGGAAGTCTCA
AGGATTTTCAATGTAAATATACGCTGCGATGAGCAACTTCTTTTAGGGTTAGCACAGCATCTAGAACCAGCTTTTTACAG
GTTGAGGATGGGTCTTGTTACTTCAAATCCTTTGATAGAGGAGATTAAAAGCTATTATAAAGATTTGTTCAGTGCGGTGG
AAAGAGCCTGTAAAATAGTTTTTTCAAAGTACAACATCATAGTACCAGAAGAAGAGATCGGATACATTACAATGCACATA
GGAGCGGCTATTGAAAGGCAAAAGGAAATGGCCAAGAAGCTTAAAGTTCTGGTGATTTGCCCTAATGGAATTGGAACTGC
CCGAATACTTTCTGCTAAATTGAAAAACAAGTTTAAAGAGATTGACCAGTTAAATATAGGAACTATTTGGGAATTCAAGA
GGAAGCATCAGGAATACGATTTGATAGTTTCTACTATAAGATTGGAAGAGGCAGATTCAAAAGTAATAATTGTATCTCCT
TTTTTGACAGAAGAAGATGAAGAGAAGATAAGAGATTATATACAAAATCTTGTCGAAAAAGTGGAACAAAAAGGTGGGCA
GTTTGAGGCTAAAGTAAAGGTAGAAGAGAATTTTGAAGTAGCAGATGAAATATTGAGAAATTTTAAAATAGAAGAAGTAG
AAGCTGATAGCACAGAAAGACTGATAGAGCTAATTGGGCAAGACCTGTCAAAATCCATGCTTGCTGAAGATGCTGAAGAA
ATAAAAGAGCTTCTCCTTAAGAGGGAAGCAATGGGCAATGTGGTTATACCTGGTACTCGAATTGCTCTTTTGCACACTCG
AAGTGATAAAATGGTACTTCCTTTTCTTGGAGTTTACAAGGTGAAAAGCCCTTTGAAACTTCAAAGCGTAGGGTTTGCCT
ACGAAGAAGTGGATACTTTTTTGATTATGCTGGCGCGTAAGACAGAAAAAAGTGATATACTAGAGATGTTAGGAAAGGTG
AGCATTTCTTTGATTGAGGACAAAAATTTTAGTGAGATTTTAAGGCTTGGGGATGTAAAAGATGTAAGAAATGCTTTGGT
GAAAATATTAAATGAGGCATAG

Upstream 100 bases:

>100_bases
TGTGCCCCATGCTAAGATTGTGACAGTGAAGAATTTCCTTGACAATACCGTGTATGACGAATTTGTAAAAAGCCTTAGAA
AATAGCTGATGGTGAAAGCC

Downstream 100 bases:

>100_bases
GAGGCGAAGTCATGGACAGAGAAATACTCAATGAAAAGAACATACTTTTAAACCTTCCTTCAGAGTCTAAAATAGAGGCT
ATTGAAAGGGTAGGGAATCT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MEDLSVRQKFILKNLIEKGPFEIADLANLMDVSERTVLREVALINERLRDFNVKIVEQGRKIFIEGEEEALKRVYSSLGA
IPLQWLLTPDQRQVLMTLQLLLSDEPIKAGYFSYQFNVVEGTISLYLDKIEEWLRMRKLTLIRRRGYGIKVEGSEVDRRN
AIIELFYNYTPMEDLLQFIYDEEKGKYFKAFFDSVFGKDLVEKVKSLCEKIKEAVYEELPDLNYFGMFVHILLSIYRSKE
GKAIELDREFINDILQSEEFNFMKKVEKILEEEDFYLPESEIAYLAIHLSPKKYVYKQHRFEELGITLEELSKEVVEEVS
RIFNVNIRCDEQLLLGLAQHLEPAFYRLRMGLVTSNPLIEEIKSYYKDLFSAVERACKIVFSKYNIIVPEEEIGYITMHI
GAAIERQKEMAKKLKVLVICPNGIGTARILSAKLKNKFKEIDQLNIGTIWEFKRKHQEYDLIVSTIRLEEADSKVIIVSP
FLTEEDEEKIRDYIQNLVEKVEQKGGQFEAKVKVEENFEVADEILRNFKIEEVEADSTERLIELIGQDLSKSMLAEDAEE
IKELLLKREAMGNVVIPGTRIALLHTRSDKMVLPFLGVYKVKSPLKLQSVGFAYEEVDTFLIMLARKTEKSDILEMLGKV
SISLIEDKNFSEILRLGDVKDVRNALVKILNEA

Sequences:

>Translated_673_residues
MEDLSVRQKFILKNLIEKGPFEIADLANLMDVSERTVLREVALINERLRDFNVKIVEQGRKIFIEGEEEALKRVYSSLGA
IPLQWLLTPDQRQVLMTLQLLLSDEPIKAGYFSYQFNVVEGTISLYLDKIEEWLRMRKLTLIRRRGYGIKVEGSEVDRRN
AIIELFYNYTPMEDLLQFIYDEEKGKYFKAFFDSVFGKDLVEKVKSLCEKIKEAVYEELPDLNYFGMFVHILLSIYRSKE
GKAIELDREFINDILQSEEFNFMKKVEKILEEEDFYLPESEIAYLAIHLSPKKYVYKQHRFEELGITLEELSKEVVEEVS
RIFNVNIRCDEQLLLGLAQHLEPAFYRLRMGLVTSNPLIEEIKSYYKDLFSAVERACKIVFSKYNIIVPEEEIGYITMHI
GAAIERQKEMAKKLKVLVICPNGIGTARILSAKLKNKFKEIDQLNIGTIWEFKRKHQEYDLIVSTIRLEEADSKVIIVSP
FLTEEDEEKIRDYIQNLVEKVEQKGGQFEAKVKVEENFEVADEILRNFKIEEVEADSTERLIELIGQDLSKSMLAEDAEE
IKELLLKREAMGNVVIPGTRIALLHTRSDKMVLPFLGVYKVKSPLKLQSVGFAYEEVDTFLIMLARKTEKSDILEMLGKV
SISLIEDKNFSEILRLGDVKDVRNALVKILNEA
>Mature_673_residues
MEDLSVRQKFILKNLIEKGPFEIADLANLMDVSERTVLREVALINERLRDFNVKIVEQGRKIFIEGEEEALKRVYSSLGA
IPLQWLLTPDQRQVLMTLQLLLSDEPIKAGYFSYQFNVVEGTISLYLDKIEEWLRMRKLTLIRRRGYGIKVEGSEVDRRN
AIIELFYNYTPMEDLLQFIYDEEKGKYFKAFFDSVFGKDLVEKVKSLCEKIKEAVYEELPDLNYFGMFVHILLSIYRSKE
GKAIELDREFINDILQSEEFNFMKKVEKILEEEDFYLPESEIAYLAIHLSPKKYVYKQHRFEELGITLEELSKEVVEEVS
RIFNVNIRCDEQLLLGLAQHLEPAFYRLRMGLVTSNPLIEEIKSYYKDLFSAVERACKIVFSKYNIIVPEEEIGYITMHI
GAAIERQKEMAKKLKVLVICPNGIGTARILSAKLKNKFKEIDQLNIGTIWEFKRKHQEYDLIVSTIRLEEADSKVIIVSP
FLTEEDEEKIRDYIQNLVEKVEQKGGQFEAKVKVEENFEVADEILRNFKIEEVEADSTERLIELIGQDLSKSMLAEDAEE
IKELLLKREAMGNVVIPGTRIALLHTRSDKMVLPFLGVYKVKSPLKLQSVGFAYEEVDTFLIMLARKTEKSDILEMLGKV
SISLIEDKNFSEILRLGDVKDVRNALVKILNEA

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 78259; Mature: 78259

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLSVRQKFILKNLIEKGPFEIADLANLMDVSERTVLREVALINERLRDFNVKIVEQGR
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCC
KIFIEGEEEALKRVYSSLGAIPLQWLLTPDQRQVLMTLQLLLSDEPIKAGYFSYQFNVVE
EEEEECHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEH
GTISLYLDKIEEWLRMRKLTLIRRRGYGIKVEGSEVDRRNAIIELFYNYTPMEDLLQFIY
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
DEEKGKYFKAFFDSVFGKDLVEKVKSLCEKIKEAVYEELPDLNYFGMFVHILLSIYRSKE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
GKAIELDREFINDILQSEEFNFMKKVEKILEEEDFYLPESEIAYLAIHLSPKKYVYKQHR
CCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHH
FEELGITLEELSKEVVEEVSRIFNVNIRCDEQLLLGLAQHLEPAFYRLRMGLVTSNPLIE
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EIKSYYKDLFSAVERACKIVFSKYNIIVPEEEIGYITMHIGAAIERQKEMAKKLKVLVIC
HHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEHHHHHHHHHHHHHHCEEEEEC
PNGIGTARILSAKLKNKFKEIDQLNIGTIWEFKRKHQEYDLIVSTIRLEEADSKVIIVSP
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHEEECCCCCEEEEEC
FLTEEDEEKIRDYIQNLVEKVEQKGGQFEAKVKVEENFEVADEILRNFKIEEVEADSTER
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHH
LIELIGQDLSKSMLAEDAEEIKELLLKREAMGNVVIPGTRIALLHTRSDKMVLPFLGVYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCEEECCHHHHH
VKSPLKLQSVGFAYEEVDTFLIMLARKTEKSDILEMLGKVSISLIEDKNFSEILRLGDVK
CCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCHHHHHHHCCHH
DVRNALVKILNEA
HHHHHHHHHHHCC
>Mature Secondary Structure
MEDLSVRQKFILKNLIEKGPFEIADLANLMDVSERTVLREVALINERLRDFNVKIVEQGR
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCC
KIFIEGEEEALKRVYSSLGAIPLQWLLTPDQRQVLMTLQLLLSDEPIKAGYFSYQFNVVE
EEEEECHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEH
GTISLYLDKIEEWLRMRKLTLIRRRGYGIKVEGSEVDRRNAIIELFYNYTPMEDLLQFIY
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
DEEKGKYFKAFFDSVFGKDLVEKVKSLCEKIKEAVYEELPDLNYFGMFVHILLSIYRSKE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
GKAIELDREFINDILQSEEFNFMKKVEKILEEEDFYLPESEIAYLAIHLSPKKYVYKQHR
CCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHH
FEELGITLEELSKEVVEEVSRIFNVNIRCDEQLLLGLAQHLEPAFYRLRMGLVTSNPLIE
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EIKSYYKDLFSAVERACKIVFSKYNIIVPEEEIGYITMHIGAAIERQKEMAKKLKVLVIC
HHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEHHHHHHHHHHHHHHCEEEEEC
PNGIGTARILSAKLKNKFKEIDQLNIGTIWEFKRKHQEYDLIVSTIRLEEADSKVIIVSP
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHEEECCCCCEEEEEC
FLTEEDEEKIRDYIQNLVEKVEQKGGQFEAKVKVEENFEVADEILRNFKIEEVEADSTER
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHH
LIELIGQDLSKSMLAEDAEEIKELLLKREAMGNVVIPGTRIALLHTRSDKMVLPFLGVYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCEEECCHHHHH
VKSPLKLQSVGFAYEEVDTFLIMLARKTEKSDILEMLGKVSISLIEDKNFSEILRLGDVK
CCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCHHHHHHHCCHH
DVRNALVKILNEA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]