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The map label for this gene is BglB [H]

Identifier: 20806855

GI number: 20806855

Start: 357649

End: 359043

Strand: Direct

Name: BglB [H]

Synonym: TTE0338

Alternate gene names: 20806855

Gene position: 357649-359043 (Clockwise)

Preceding gene: 20806854

Following gene: 20806856

Centisome position: 13.3

GC content: 33.69

Gene sequence:

>1395_bases
ATGTCTAAAGAATACAGATTTCCAGAAGGTTTTTGGTGGGGTTCGGCAACATCAGCAGTGCAAATTGAAGGGGCTGCAGA
TGAAGACGGTAAAGGGATGAATGTATGGGATTATTGGTATCAGAAAGAACCTAATCGCTTTTTTAATGGAATAGGGTCTC
AAGTAACATCTGATTTTTATCATAGATATAAAGAAGATATAAAACTTATGAAAGAGTTGGGGCACAATTCATTTAGATTT
TCTATTTCATGGTCTCGTCTAATTCCTGGTGGCACAGGTAAAGTTAACGAAAAAGCAGTAGAATTTTACAACAATGTTAT
TAATGAGCTCTTGGAAAATGGTATCGAACCTTTTGCTACCCTTTTTCACTTTGACATGCCTATAGAAATGCAAAATATTG
GAGGTTTTGAGAATAGAAAAGTAGTAGAATATTTTGCTGAATATGCTAAGACATGTTTTGAGTTGTTTGGTGATAGAGTA
AAAAGATGGATAACATTTAATGAACCGATAGTTCCCGTATTAGGTGGGTATTTATATAATTTCCATTATCCAGATATAGT
GGATTTTAAAAGAGCAGTGCAATTCGGTTATGGCACAGTATTAGCAAGTGCGAGGGCAATAGAGGAATTTAAAAAACTAA
AAATAAATGATGCTAAAATAGGTATTGTTTTAAACTTGAGTCCTGTTTATCCAAGAAGTAATCATCCGGCAGATTTAAAA
GCAGCGGAGCTTGCGGATTTGTTTCATAATAGAAGTTTTCTTGACCCTTCCGTTAAAGGGGAGTATCCTAAAGAATTAGT
AGAAGTTTTAAAAGCTTACAATCATTTGCCGGAATATAAGGAAGAAGATTTAGAATTAATAAAAGATAATACTGTACAAT
ATTTAGGAGTAAATTATTATCAGCCGCTTAGAGTTAAAGCTAAAGAGAATATGCCAAATCCATATGGTGTATTTACACCC
AATTGGTTTTATGATGAGTATATTATGCCAGGTAGGAGAATGAATCCTTATAGAGGATGGGAAATCTACGAAAAAGGGAT
ATATGATCTTCTGAAAAGAATAAAAGATGAATATGGAAACATAGAGTGTTTTATTTCAGAAAATGGAATGGGAGTGGAAG
GGGAAGAACGCTTTATAAAAGATGGTATTATTCAAGACGACTATAGGATTGAATTTATAAAAGAGCATTTAAAATGGGTT
CATAAAGCAATTGAAGAGGGATGCAATGTCAAAGGATATCATGTATGGACATTTATGGACAATTGGTCGTGGCTTAATGC
GTATAAAAACCGTTATGGGCTCGTAGCGATAGATTTAAAAACGCAAAAGCGTACAATAAAAAAGAGTGGTTATTGGTTTA
AAGAAGTGGCAGAAAATAATGGCTTTGTCGATTAA

Upstream 100 bases:

>100_bases
AAAGAATATTTACCGCAATATAAGTAATAATAGAAATTACCTCTCTTTGTTTTCTAGAATTATGTTTCAAAATCACTTTA
ACATGAGGAGTGAAATTCCT

Downstream 100 bases:

>100_bases
CCCCGGTTTTCCCGGGGTTTTTTCTTTTTTCAATTTTGTCATAGAAAACGAATGACAAGACTGAGTTTCTTTTAATTGCA
TAAAAAAAGAAGGGGGATTA

Product: Beta-glucosidase/6-phospho-beta- glucosidase/beta- galactosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSKEYRFPEGFWWGSATSAVQIEGAADEDGKGMNVWDYWYQKEPNRFFNGIGSQVTSDFYHRYKEDIKLMKELGHNSFRF
SISWSRLIPGGTGKVNEKAVEFYNNVINELLENGIEPFATLFHFDMPIEMQNIGGFENRKVVEYFAEYAKTCFELFGDRV
KRWITFNEPIVPVLGGYLYNFHYPDIVDFKRAVQFGYGTVLASARAIEEFKKLKINDAKIGIVLNLSPVYPRSNHPADLK
AAELADLFHNRSFLDPSVKGEYPKELVEVLKAYNHLPEYKEEDLELIKDNTVQYLGVNYYQPLRVKAKENMPNPYGVFTP
NWFYDEYIMPGRRMNPYRGWEIYEKGIYDLLKRIKDEYGNIECFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWV
HKAIEEGCNVKGYHVWTFMDNWSWLNAYKNRYGLVAIDLKTQKRTIKKSGYWFKEVAENNGFVD

Sequences:

>Translated_464_residues
MSKEYRFPEGFWWGSATSAVQIEGAADEDGKGMNVWDYWYQKEPNRFFNGIGSQVTSDFYHRYKEDIKLMKELGHNSFRF
SISWSRLIPGGTGKVNEKAVEFYNNVINELLENGIEPFATLFHFDMPIEMQNIGGFENRKVVEYFAEYAKTCFELFGDRV
KRWITFNEPIVPVLGGYLYNFHYPDIVDFKRAVQFGYGTVLASARAIEEFKKLKINDAKIGIVLNLSPVYPRSNHPADLK
AAELADLFHNRSFLDPSVKGEYPKELVEVLKAYNHLPEYKEEDLELIKDNTVQYLGVNYYQPLRVKAKENMPNPYGVFTP
NWFYDEYIMPGRRMNPYRGWEIYEKGIYDLLKRIKDEYGNIECFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWV
HKAIEEGCNVKGYHVWTFMDNWSWLNAYKNRYGLVAIDLKTQKRTIKKSGYWFKEVAENNGFVD
>Mature_463_residues
SKEYRFPEGFWWGSATSAVQIEGAADEDGKGMNVWDYWYQKEPNRFFNGIGSQVTSDFYHRYKEDIKLMKELGHNSFRFS
ISWSRLIPGGTGKVNEKAVEFYNNVINELLENGIEPFATLFHFDMPIEMQNIGGFENRKVVEYFAEYAKTCFELFGDRVK
RWITFNEPIVPVLGGYLYNFHYPDIVDFKRAVQFGYGTVLASARAIEEFKKLKINDAKIGIVLNLSPVYPRSNHPADLKA
AELADLFHNRSFLDPSVKGEYPKELVEVLKAYNHLPEYKEEDLELIKDNTVQYLGVNYYQPLRVKAKENMPNPYGVFTPN
WFYDEYIMPGRRMNPYRGWEIYEKGIYDLLKRIKDEYGNIECFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWVH
KAIEEGCNVKGYHVWTFMDNWSWLNAYKNRYGLVAIDLKTQKRTIKKSGYWFKEVAENNGFVD

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=482, Percent_Identity=32.1576763485477, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI32481206, Length=481, Percent_Identity=33.2640332640333, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI110681710, Length=485, Percent_Identity=31.7525773195876, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI28376633, Length=470, Percent_Identity=27.8723404255319, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI24497614, Length=480, Percent_Identity=27.5, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI190360571, Length=97, Percent_Identity=45.360824742268, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI2367270, Length=484, Percent_Identity=33.0578512396694, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1789070, Length=481, Percent_Identity=34.3035343035343, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI2367174, Length=506, Percent_Identity=30.8300395256917, Blast_Score=213, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17552856, Length=477, Percent_Identity=34.1719077568134, Blast_Score=255, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17539390, Length=472, Percent_Identity=34.7457627118644, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21356577, Length=488, Percent_Identity=31.1475409836066, Blast_Score=239, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54505; Mature: 54374

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEYRFPEGFWWGSATSAVQIEGAADEDGKGMNVWDYWYQKEPNRFFNGIGSQVTSDFY
CCCCCCCCCCEECCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
HRYKEDIKLMKELGHNSFRFSISWSRLIPGGTGKVNEKAVEFYNNVINELLENGIEPFAT
HHHHHHHHHHHHCCCCCEEEEEEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
LFHFDMPIEMQNIGGFENRKVVEYFAEYAKTCFELFGDRVKRWITFNEPIVPVLGGYLYN
HHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHC
FHYPDIVDFKRAVQFGYGTVLASARAIEEFKKLKINDAKIGIVLNLSPVYPRSNHPADLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCH
AAELADLFHNRSFLDPSVKGEYPKELVEVLKAYNHLPEYKEEDLELIKDNTVQYLGVNYY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCC
QPLRVKAKENMPNPYGVFTPNWFYDEYIMPGRRMNPYRGWEIYEKGIYDLLKRIKDEYGN
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IECFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWVHKAIEEGCNVKGYHVWTFMD
EEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
NWSWLNAYKNRYGLVAIDLKTQKRTIKKSGYWFKEVAENNGFVD
CCHHHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SKEYRFPEGFWWGSATSAVQIEGAADEDGKGMNVWDYWYQKEPNRFFNGIGSQVTSDFY
CCCCCCCCCEECCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
HRYKEDIKLMKELGHNSFRFSISWSRLIPGGTGKVNEKAVEFYNNVINELLENGIEPFAT
HHHHHHHHHHHHCCCCCEEEEEEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
LFHFDMPIEMQNIGGFENRKVVEYFAEYAKTCFELFGDRVKRWITFNEPIVPVLGGYLYN
HHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHC
FHYPDIVDFKRAVQFGYGTVLASARAIEEFKKLKINDAKIGIVLNLSPVYPRSNHPADLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCH
AAELADLFHNRSFLDPSVKGEYPKELVEVLKAYNHLPEYKEEDLELIKDNTVQYLGVNYY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCC
QPLRVKAKENMPNPYGVFTPNWFYDEYIMPGRRMNPYRGWEIYEKGIYDLLKRIKDEYGN
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IECFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWVHKAIEEGCNVKGYHVWTFMD
EEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
NWSWLNAYKNRYGLVAIDLKTQKRTIKKSGYWFKEVAENNGFVD
CCHHHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]