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The map label for this gene is uppP

Identifier: 20094648

GI number: 20094648

Start: 1202106

End: 1202915

Strand: Reverse

Name: uppP

Synonym: MK1212

Alternate gene names: 20094648

Gene position: 1202915-1202106 (Counterclockwise)

Preceding gene: 20094662

Following gene: 20094647

Centisome position: 70.97

GC content: 65.31

Gene sequence:

>810_bases
GTGCGGGAGATCGAGTTATGGACCGCCGTCCTGGCCGGCGTGGTGCAAGGTATCACGGAGTGGTTACCGATCAGCAGCGA
AGGTCAGGCGACGATGACGATGATGAAGGTACTCGGGATCCCGCCCTCGACCGCGATGGACCTGGCGCTCTGGCTGCACG
CCGGCACGCTGCTCGCCGTGCTGTTACGGTTCGGTGTCCCGTACTGGCTGACGGTGAGGGACCTGCTGATGGGCGGGCCG
TGGCGGCGATTAGGATTGTTCGCGATCGTCGCCACGGTCTGTACGGCCGTCGTCGGGCTCCCGGTGTACAAGGTGTTGAA
GGGGATCTTCTCGGCCGCCACGGGAGACGCGGTCCAGATGGCCATCGGAGGCGCCCTGATCGTCACGGGACTCCTCCTGC
GGATATCGCCCGAGGGGCTGAGGGATCGCAGGGAAGTCAACGTCGTGGACGCCGTCATCGTGGGCCTGGGACAGGGGTTC
TCGGTGATCCCGGGGATCAGCCGGTCCGGTACGACGATGGCGCTCCTGCTCTGGCGTAGGTTCGACGGTGGAGAGGCCGT
GTGGCTGTCGTTCTACCTGGCCGGTCCGGCGATGCTGGGCGCGACGGCCTTAGAGCTCAAGGAGGGGCTGAGCGCGGCCA
CGAAAATGGGCACGTCGTGGATGGTGACGGCGATCGGGGTGTCCTTCGTCGTGAGTCTGATCTGCATGGAAGTGCTGCTG
CGGGTGGCGAGACGTCTCGACTTCTCGAAAGTGTGTCTGCTGTTGGGTGGGATCGCGCTCCTCGTGCCGCTCGCAGCCAA
GATGCTCTGA

Upstream 100 bases:

>100_bases
GTGGAGATACCCGACCCGCGGCGTCAGATTACGGTAATCGCCTTCCGACTCCGGATTCCGAACAGAGATTTAACCTCGGG
CGGTCGCGGCGGCGGAGGGG

Downstream 100 bases:

>100_bases
GGAGGGGTGGTGAAGATCGGGGCCCGGGAGCTGGCCGCCGTGGCGATCGGAGGCGCGCTGGGGGCGGTCTGTCGCTACTT
ACTGTCCGGTCTCGTACCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MREIELWTAVLAGVVQGITEWLPISSEGQATMTMMKVLGIPPSTAMDLALWLHAGTLLAVLLRFGVPYWLTVRDLLMGGP
WRRLGLFAIVATVCTAVVGLPVYKVLKGIFSAATGDAVQMAIGGALIVTGLLLRISPEGLRDRREVNVVDAVIVGLGQGF
SVIPGISRSGTTMALLLWRRFDGGEAVWLSFYLAGPAMLGATALELKEGLSAATKMGTSWMVTAIGVSFVVSLICMEVLL
RVARRLDFSKVCLLLGGIALLVPLAAKML

Sequences:

>Translated_269_residues
MREIELWTAVLAGVVQGITEWLPISSEGQATMTMMKVLGIPPSTAMDLALWLHAGTLLAVLLRFGVPYWLTVRDLLMGGP
WRRLGLFAIVATVCTAVVGLPVYKVLKGIFSAATGDAVQMAIGGALIVTGLLLRISPEGLRDRREVNVVDAVIVGLGQGF
SVIPGISRSGTTMALLLWRRFDGGEAVWLSFYLAGPAMLGATALELKEGLSAATKMGTSWMVTAIGVSFVVSLICMEVLL
RVARRLDFSKVCLLLGGIALLVPLAAKML
>Mature_269_residues
MREIELWTAVLAGVVQGITEWLPISSEGQATMTMMKVLGIPPSTAMDLALWLHAGTLLAVLLRFGVPYWLTVRDLLMGGP
WRRLGLFAIVATVCTAVVGLPVYKVLKGIFSAATGDAVQMAIGGALIVTGLLLRISPEGLRDRREVNVVDAVIVGLGQGF
SVIPGISRSGTTMALLLWRRFDGGEAVWLSFYLAGPAMLGATALELKEGLSAATKMGTSWMVTAIGVSFVVSLICMEVLL
RVARRLDFSKVCLLLGGIALLVPLAAKML

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=265, Percent_Identity=30.5660377358491, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_METKA (Q8TW25)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614495.1
- GeneID:   1477807
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1212
- NMPDR:   fig|190192.1.peg.1208
- HOGENOM:   HBG391969
- OMA:   WVIYATI
- BioCyc:   MKAN190192:MK1212-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28623; Mature: 28623

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe102a30)-; HASH(0xe01394c)-; HASH(0xe628078)-; HASH(0xe607c94)-; HASH(0xe238428)-; HASH(0xe1029dc)-; HASH(0xe627db4)-; HASH(0xdc62128)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIELWTAVLAGVVQGITEWLPISSEGQATMTMMKVLGIPPSTAMDLALWLHAGTLLAV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLRFGVPYWLTVRDLLMGGPWRRLGLFAIVATVCTAVVGLPVYKVLKGIFSAATGDAVQM
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AIGGALIVTGLLLRISPEGLRDRREVNVVDAVIVGLGQGFSVIPGISRSGTTMALLLWRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
FDGGEAVWLSFYLAGPAMLGATALELKEGLSAATKMGTSWMVTAIGVSFVVSLICMEVLL
CCCCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RVARRLDFSKVCLLLGGIALLVPLAAKML
HHHHHCCHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MREIELWTAVLAGVVQGITEWLPISSEGQATMTMMKVLGIPPSTAMDLALWLHAGTLLAV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLRFGVPYWLTVRDLLMGGPWRRLGLFAIVATVCTAVVGLPVYKVLKGIFSAATGDAVQM
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AIGGALIVTGLLLRISPEGLRDRREVNVVDAVIVGLGQGFSVIPGISRSGTTMALLLWRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
FDGGEAVWLSFYLAGPAMLGATALELKEGLSAATKMGTSWMVTAIGVSFVVSLICMEVLL
CCCCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RVARRLDFSKVCLLLGGIALLVPLAAKML
HHHHHCCHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11930014