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The map label for this gene is 20094037

Identifier: 20094037

GI number: 20094037

Start: 557225

End: 558235

Strand: Direct

Name: 20094037

Synonym: MK0599

Alternate gene names: NA

Gene position: 557225-558235 (Clockwise)

Preceding gene: 20094036

Following gene: 20094039

Centisome position: 32.88

GC content: 63.5

Gene sequence:

>1011_bases
GTGCCTGAGCTCCCCTACGTCGCCGTCCCCAAACATATGGCGGAACGCGCTAGGAGGGTACTGTCTCGAGAGGATCTTCT
CGCCAAGGACGTCAAAGCGCGACGAGAAGAGGACATGGTGCTTTTTCCCGTACGCGATGCCGGACGTGCGGGCAGTGTGC
TCGAAGAACTCGGGATACCCTACGAAGCGGGTGAAGCCGAGTTCGAACGGACAGTCGAACACCGGAGCGTAGAGGAGGTC
CTCGAAGACAGCTTCGGATGGTCCGTGCCCGTACCTTACGACGTGATCGGCGACGTGGCCGTGGTTCAAATACCCGACGA
GCTGCGTGGGCACGAACGCGAAGTCGGCCGGGCGATCATGAAAGTTCACCGACGGGTGAGGGCGGTCTTCGAGCGCGGTC
CCGTCCGGGGAGTCTTCCGCGTTCGGGACCTCCGCCGCATAGCCGGGAAGGGCCCCGCGGTGACCGAACATCGAGAGCAC
AGGTGCAGGTTCCGGGTCGATCTGGCGCGGTGTTACTTCAACCCTAGGCTGGCCACCGAGCGCCGGTTGCTCGCCGAGGA
CGTCGTGGAGGAAGGATCCACGGTACTCGACCTTTTCGCCGGCGTGGGTCCCATCACGGTGATCCTGAAGCGGTTCGTCC
CGAGCGTAGAGGTGACCGCCTGCGAACTGAACCCAGTCGCGTACAGGTACCTCCTGGAGAACCTCCGGCTGAACAGGGTC
GAGGCGAGGGCCTTCCTGGGCGATGCACGCGAGGTGTCGCGGCTGGTGGGGCGGTTCGACTACGTGATCATGAACGTACC
CAAGATGGCGCACCGGTTCGTCGAAACCGCGGTACGGTGTGTACGGCCCGAGGGTAGGCTGATCTACTACCGGATAGCTC
CGAACGCCGAGGAAGCGTTCGAGGAGCTCCGTAGGAAGGCCGATAGACCGGTGGAACTCGAGTCTCACCGGGAGGTGAAG
CCGTACTCCCCGGAGGAGTCGCTTTACCGGCTCGTGGTCCGCGTTCACTGA

Upstream 100 bases:

>100_bases
CTACTTCAACAGATCCGGTTACTTGGTGCTCGTCAGCCACGGTAAGACGACGAAGATACGCGTCCTTCCGCTGATACCAC
TGATCTGAGGGGTCTCAATC

Downstream 100 bases:

>100_bases
TTCAGACGCTTTCTCAGCTCGTGGAGTAGGATCGCTACGGCGCCTACCTCACCCACGTTACGCTCCGTACCCACGTACAC
GGCCTCGTCACCGAGCTCGA

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPELPYVAVPKHMAERARRVLSREDLLAKDVKARREEDMVLFPVRDAGRAGSVLEELGIPYEAGEAEFERTVEHRSVEEV
LEDSFGWSVPVPYDVIGDVAVVQIPDELRGHEREVGRAIMKVHRRVRAVFERGPVRGVFRVRDLRRIAGKGPAVTEHREH
RCRFRVDLARCYFNPRLATERRLLAEDVVEEGSTVLDLFAGVGPITVILKRFVPSVEVTACELNPVAYRYLLENLRLNRV
EARAFLGDAREVSRLVGRFDYVIMNVPKMAHRFVETAVRCVRPEGRLIYYRIAPNAEEAFEELRRKADRPVELESHREVK
PYSPEESLYRLVVRVH

Sequences:

>Translated_336_residues
MPELPYVAVPKHMAERARRVLSREDLLAKDVKARREEDMVLFPVRDAGRAGSVLEELGIPYEAGEAEFERTVEHRSVEEV
LEDSFGWSVPVPYDVIGDVAVVQIPDELRGHEREVGRAIMKVHRRVRAVFERGPVRGVFRVRDLRRIAGKGPAVTEHREH
RCRFRVDLARCYFNPRLATERRLLAEDVVEEGSTVLDLFAGVGPITVILKRFVPSVEVTACELNPVAYRYLLENLRLNRV
EARAFLGDAREVSRLVGRFDYVIMNVPKMAHRFVETAVRCVRPEGRLIYYRIAPNAEEAFEELRRKADRPVELESHREVK
PYSPEESLYRLVVRVH
>Mature_335_residues
PELPYVAVPKHMAERARRVLSREDLLAKDVKARREEDMVLFPVRDAGRAGSVLEELGIPYEAGEAEFERTVEHRSVEEVL
EDSFGWSVPVPYDVIGDVAVVQIPDELRGHEREVGRAIMKVHRRVRAVFERGPVRGVFRVRDLRRIAGKGPAVTEHREHR
CRFRVDLARCYFNPRLATERRLLAEDVVEEGSTVLDLFAGVGPITVILKRFVPSVEVTACELNPVAYRYLLENLRLNRVE
ARAFLGDAREVSRLVGRFDYVIMNVPKMAHRFVETAVRCVRPEGRLIYYRIAPNAEEAFEELRRKADRPVELESHREVKP
YSPEESLYRLVVRVH

Specific function: Unknown

COG id: COG2520

COG function: function code R; Predicted methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ1557 and to yeast YHR070w [H]

Homologues:

Organism=Homo sapiens, GI145275187, Length=244, Percent_Identity=26.6393442622951, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321861, Length=179, Percent_Identity=31.8435754189944, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45551508, Length=233, Percent_Identity=25.3218884120172, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10 [H]

EC number: NA

Molecular weight: Translated: 38755; Mature: 38624

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELPYVAVPKHMAERARRVLSREDLLAKDVKARREEDMVLFPVRDAGRAGSVLEELGIP
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCC
YEAGEAEFERTVEHRSVEEVLEDSFGWSVPVPYDVIGDVAVVQIPDELRGHEREVGRAIM
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEECCHHHCCHHHHHHHHHH
KVHRRVRAVFERGPVRGVFRVRDLRRIAGKGPAVTEHREHRCRFRVDLARCYFNPRLATE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
RRLLAEDVVEEGSTVLDLFAGVGPITVILKRFVPSVEVTACELNPVAYRYLLENLRLNRV
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCHH
EARAFLGDAREVSRLVGRFDYVIMNVPKMAHRFVETAVRCVRPEGRLIYYRIAPNAEEAF
HHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
EELRRKADRPVELESHREVKPYSPEESLYRLVVRVH
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PELPYVAVPKHMAERARRVLSREDLLAKDVKARREEDMVLFPVRDAGRAGSVLEELGIP
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCC
YEAGEAEFERTVEHRSVEEVLEDSFGWSVPVPYDVIGDVAVVQIPDELRGHEREVGRAIM
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEECCHHHCCHHHHHHHHHH
KVHRRVRAVFERGPVRGVFRVRDLRRIAGKGPAVTEHREHRCRFRVDLARCYFNPRLATE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
RRLLAEDVVEEGSTVLDLFAGVGPITVILKRFVPSVEVTACELNPVAYRYLLENLRLNRV
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCHH
EARAFLGDAREVSRLVGRFDYVIMNVPKMAHRFVETAVRCVRPEGRLIYYRIAPNAEEAF
HHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
EELRRKADRPVELESHREVKPYSPEESLYRLVVRVH
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]