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The map label for this gene is nikR [C]

Identifier: 197119923

GI number: 197119923

Start: 4075651

End: 4076070

Strand: Direct

Name: nikR [C]

Synonym: Gbem_3562

Alternate gene names: 197119923

Gene position: 4075651-4076070 (Clockwise)

Preceding gene: 197119922

Following gene: 197119924

Centisome position: 88.31

GC content: 59.29

Gene sequence:

>420_bases
ATGGGTGAGACAGTAAGGTTTGGTATATCAATGGACGACCAATTGCTTGAGAGTTTCGACAGGCTCATTGAGCAGAAAGG
TTACGCCAATCGCTCCGAGGCGATCCGCGACCTGATCCGGGCGGCCCAGGTAGAGCTCGACTGGGAAGAAGGGGAAAAAG
AAGGCGTCGGCACCGTCACCCTCGTCTACAACCACCACGTCCGCGATCTTTCCGACAAGCTCACCGAGCACCAGCACGCG
CATCACGACCAGATCATCTCCGCACTGCACGTCCATCTCGACGCCCACAACTGCCTCGAAGTGCTCGTGGTGCGTGGCAA
GGCCCGCGACGTGCGCAGGATTGCCGACGAACTGATCGGGGTCAAGGGAGTGAAGCACGGCAAACTGGTCATGACCACCA
CCGGCGAAGGCCTGCACTGA

Upstream 100 bases:

>100_bases
TACCTCCGTGACCTCTGTGTTCCGCCTTTCTCCGCCTTACGTTTTTGACTCCGGAAGCTGTTTCACGTATAGTGTGGCAC
CTTCACAAGGAGAGTCATGC

Downstream 100 bases:

>100_bases
CTCTCCTGCATTCCCGCTCGAAGAATTGCAGCCTAAGTTCCCCCTCCCCCTGCGGGAGGGGGCAGGGGGTGGGGGAACGC
GCCACCCATTGAAAGCTTGC

Product: nickel responsive regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MGETVRFGISMDDQLLESFDRLIEQKGYANRSEAIRDLIRAAQVELDWEEGEKEGVGTVTLVYNHHVRDLSDKLTEHQHA
HHDQIISALHVHLDAHNCLEVLVVRGKARDVRRIADELIGVKGVKHGKLVMTTTGEGLH

Sequences:

>Translated_139_residues
MGETVRFGISMDDQLLESFDRLIEQKGYANRSEAIRDLIRAAQVELDWEEGEKEGVGTVTLVYNHHVRDLSDKLTEHQHA
HHDQIISALHVHLDAHNCLEVLVVRGKARDVRRIADELIGVKGVKHGKLVMTTTGEGLH
>Mature_138_residues
GETVRFGISMDDQLLESFDRLIEQKGYANRSEAIRDLIRAAQVELDWEEGEKEGVGTVTLVYNHHVRDLSDKLTEHQHAH
HDQIISALHVHLDAHNCLEVLVVRGKARDVRRIADELIGVKGVKHGKLVMTTTGEGLH

Specific function: Transcriptional regulator (Potential)

COG id: COG0864

COG function: function code K; Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory CopG/NikR family

Homologues:

Organism=Escherichia coli, GI1789892, Length=108, Percent_Identity=40.7407407407407, Blast_Score=94, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NIKR_GEOBB (B5EC98)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002140350.1
- GeneID:   6780425
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_3562
- HOGENOM:   HBG646378
- OMA:   CLEVLVV
- ProtClustDB:   PRK04460
- GO:   GO:0006350
- HAMAP:   MF_00476
- InterPro:   IPR013321
- InterPro:   IPR002145
- InterPro:   IPR022988
- InterPro:   IPR010985
- InterPro:   IPR014864
- Gene3D:   G3DSA:1.10.1220.10
- Gene3D:   G3DSA:3.30.70.1150

Pfam domain/function: PF08753 NikR_C; PF01402 RHH_1; SSF47598 Met_repress_like

EC number: NA

Molecular weight: Translated: 15675; Mature: 15544

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETVRFGISMDDQLLESFDRLIEQKGYANRSEAIRDLIRAAQVELDWEEGEKEGVGTVT
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LVYNHHVRDLSDKLTEHQHAHHDQIISALHVHLDAHNCLEVLVVRGKARDVRRIADELIG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VKGVKHGKLVMTTTGEGLH
CCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
GETVRFGISMDDQLLESFDRLIEQKGYANRSEAIRDLIRAAQVELDWEEGEKEGVGTVT
CCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LVYNHHVRDLSDKLTEHQHAHHDQIISALHVHLDAHNCLEVLVVRGKARDVRRIADELIG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VKGVKHGKLVMTTTGEGLH
CCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA