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The map label for this gene is tadA [H]

Identifier: 197119924

GI number: 197119924

Start: 4076204

End: 4076704

Strand: Direct

Name: tadA [H]

Synonym: Gbem_3563

Alternate gene names: 197119924

Gene position: 4076204-4076704 (Clockwise)

Preceding gene: 197119923

Following gene: 197119925

Centisome position: 88.32

GC content: 59.28

Gene sequence:

>501_bases
ATGCAAAGAGACGATCACTACTGGATGGGCAAGGCAATAGCGCAGGCAAGAAGGGCCGAAGCGATAGGCGAAGTACCGAT
AGGCGCCGTCATAGTCAAGGATGGGGTCATCATCGCACGGGGGCACAACCTCAGGGAGAGCAACCAGGACCCCGCGGCGC
ATGCCGAGATGATCGCCATCCGCAAGGCGGCGAAGAAGCTGGCCAGTTGGCGCCTGACCGGCGCGACCCTGTACGTGACC
CTTGAGCCCTGCACCATGTGCATGGGAGCCGTCATCCTCTCCCGCCTGGACCGCGTCGTTTTCGGGAGTTACGATCCAAA
GGGAGGAGCCGCCGGATCTCTCTACGACCTTTCCGACGACAAGAGGCTGAACCACAGCGTCGTACTCACCCCCGGGGTCA
GGGGCGAAGAAACATCCTCCATGCTGTCCGGGTTTTTCGCCGAACTGAGGGCGAAGAAAAAGAGCGTGAATAAATCCTCA
CCCACTTCCGAAAATAGTTAA

Upstream 100 bases:

>100_bases
TAAGTTCCCCCTCCCCCTGCGGGAGGGGGCAGGGGGTGGGGGAACGCGCCACCCATTGAAAGCTTGCCCCCTACATAAGT
TGAAGATCCAAAGGAACAAG

Downstream 100 bases:

>100_bases
ACATTTTTCGCCCCCTGCCGAATAGGCAAAACGAAACAAGTTTCTTCGCTTGAAGAGGGGCGCCTATGCAAACAGACGAA
ATCACCCCCATTGCCGTCAT

Product: tRNA (adenosine-34) deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MQRDDHYWMGKAIAQARRAEAIGEVPIGAVIVKDGVIIARGHNLRESNQDPAAHAEMIAIRKAAKKLASWRLTGATLYVT
LEPCTMCMGAVILSRLDRVVFGSYDPKGGAAGSLYDLSDDKRLNHSVVLTPGVRGEETSSMLSGFFAELRAKKKSVNKSS
PTSENS

Sequences:

>Translated_166_residues
MQRDDHYWMGKAIAQARRAEAIGEVPIGAVIVKDGVIIARGHNLRESNQDPAAHAEMIAIRKAAKKLASWRLTGATLYVT
LEPCTMCMGAVILSRLDRVVFGSYDPKGGAAGSLYDLSDDKRLNHSVVLTPGVRGEETSSMLSGFFAELRAKKKSVNKSS
PTSENS
>Mature_166_residues
MQRDDHYWMGKAIAQARRAEAIGEVPIGAVIVKDGVIIARGHNLRESNQDPAAHAEMIAIRKAAKKLASWRLTGATLYVT
LEPCTMCMGAVILSRLDRVVFGSYDPKGGAAGSLYDLSDDKRLNHSVVLTPGVRGEETSSMLSGFFAELRAKKKSVNKSS
PTSENS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=164, Percent_Identity=30.4878048780488, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI145693172, Length=158, Percent_Identity=44.9367088607595, Blast_Score=141, Evalue=2e-35,
Organism=Escherichia coli, GI1786616, Length=156, Percent_Identity=32.6923076923077, Blast_Score=63, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=44.3298969072165, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17555996, Length=97, Percent_Identity=41.2371134020619, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=32.8859060402685, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355527, Length=159, Percent_Identity=30.8176100628931, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17960; Mature: 17960

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRDDHYWMGKAIAQARRAEAIGEVPIGAVIVKDGVIIARGHNLRESNQDPAAHAEMIAI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHH
RKAAKKLASWRLTGATLYVTLEPCTMCMGAVILSRLDRVVFGSYDPKGGAAGSLYDLSDD
HHHHHHHHHEEECCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
KRLNHSVVLTPGVRGEETSSMLSGFFAELRAKKKSVNKSSPTSENS
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQRDDHYWMGKAIAQARRAEAIGEVPIGAVIVKDGVIIARGHNLRESNQDPAAHAEMIAI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHH
RKAAKKLASWRLTGATLYVTLEPCTMCMGAVILSRLDRVVFGSYDPKGGAAGSLYDLSDD
HHHHHHHHHEEECCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
KRLNHSVVLTPGVRGEETSSMLSGFFAELRAKKKSVNKSSPTSENS
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]